444 research outputs found

    Standard Young Tableaux and Colored Motzkin Paths

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    In this paper, we propose a notion of colored Motzkin paths and establish a bijection between the nn-cell standard Young tableaux (SYT) of bounded height and the colored Motzkin paths of length nn. This result not only gives a lattice path interpretation of the standard Young tableaux but also reveals an unexpected intrinsic relation between the set of SYTs with at most 2d+12d+1 rows and the set of SYTs with at most 2d rows.Comment: 21 page

    Total Parenteral Nutrition Treatment in a Diabetic Pregnant Woman Complicated with Hyperemesis Gravidarum, Malnutrition, and Intrauterine Growth Restriction

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    SummaryObjectiveWe report a case of a pregnant woman with diabetes, complicated with hyperemesis gravidarum, malnutrition, and intrauterine growth restriction, who was treated beneficially with total parenteral nutrition.Case ReportA 26-year-old diabetic nullipara complained of severe nausea and vomiting from early in her pregnancy. Malnutrition developed at about 24 weeks of gestation. In spite of treatment with antiemetics, antihistamine, and vitamin B6, the symptoms persisted, and intrauterine growth restriction eventually developed. Total parenteral nutrition was commenced at 29 weeks of gestation. She delivered a healthy female neonate with a birth body weight of 2,120 g at 36 weeks of gestation by cesarean section. Total parenteral nutrition was gradually tapered off 1 week later, and the mother was discharged from hospital in good condition 10 days after delivery.ConclusionTotal parenteral nutrition may be used to treat diabetic patients with hyperemesis gravidarum who develop malnutrition causing intrauterine growth restriction

    Microstructural differences in white matter tracts across middle to late adulthood : a diffusion MRI study on 7167 UK Biobank participants

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    Acknowledgements This research was approved by the UK Biobank (application number: 24089) and was supported by the Roland Sutton Academic Trust (grant number: 0039/R/16) and Taiwan National Health Research Institute (NHRI-EX109-10928NI). We acknowledge the valuable contributions of members of the UK Biobank Imaging Working Group and the UK Biobank coordinating center. The UK Biobank (including the imaging enhancement) was supported by the UK Medical Research Council and the Wellcome Trust. The authors are grateful for the provision of simultaneous multislice (multiband) pulse sequence and reconstruction algorithms by the Center for Magnetic Resonance Research, University of Minnesota. Finally, the authors are extremely grateful to all UK Biobank study participants, who have generously donated their time to make this resource possible. This article was edited by Wallace Academic Editing.Peer reviewedPostprin

    Isolated pancreatic metastasis from rectal cancer: a case report and review of literature

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    Isolated pancreatic metastases from a non-pancreatic primary malignancy are very rare. Studies have shown that resection of metastases is of proven benefit in some types of tumors. We report a case of 76-year-old Taiwanese woman with rectal adenocarcinoma treated with neoadjuvant chemoradiotherapy and abdominoperineal resection 2 years ago presenting with an asymptomatic mass at the pancreatic tail on a routine follow up abdominal computed tomography scan. The patient underwent distal pancreatectomy and splenectomy under the preoperative impression of a primary pancreatic malignancy. Histological examination of the surgical specimen showed metastatic adenocarcinoma. Immunohistochemical studies confirmed the diagnosis of pancreatic metastasis from rectal adenocarcinoma. Postoperative chemotherapy in the form of oral capecitabine was given. The patient is alive and disease free 12 months after the surgery. In a patient presenting with a pancreatic mass with history of a non-pancreatic malignancy, a differential diagnosis of pancreatic metastasis should be considered. Surgical resection of a solitary pancreatic mass is justified not only to get the definitive diagnosis but also to improve the survival

    Applying a Comprehensive Action Determination Model to Examine the Recycling Behavior of Taipei City Residents

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    With the occurrence of rapid global economic growth concerns about waste and its related effects on the environment are on the rise. There has been an increasing focus towards sustainable development and waste recycling as part of environmental sustainability strategies, and the encouraging of recycling behavior has received considerable attention from various environmental stakeholders. While numerous studies have used grounded theories such as the theory of planned behaviors and the norm activation model to examine environmental behaviors, a lack of consideration of other important variables in these studies has been revealed. This study aimed to address this gap by adopting the comprehensive action determination model, which comprises a wider group of influencing variables related to norms, intentions, situations, and habits. This model was tested using structural equation modelling with a sample of 386 valid questionnaires collected from Taipei City residents in the domain of recycling behaviors. Results indicated that awareness had a positive influence on personal norms towards recycling behaviors; social norms had a positive influence on personal norms towards recycling behaviors; attitudes had a positive influence on recycling intentions; social norms had a positive influence on recycling intentions; personal norms had a positive influence on recycling intentions; perceived behavior control had a positive influence on recycling intentions; recycling intentions had a positive influence on recycling behavior; and recycling habits had a positive influence on recycling behavior. However, findings did not support the positive impact of perceived behavioral control on recycling behavior

    Technology-Enhanced Learning for Graduate Students: Exploring the Correlation of Media Richness and Creativity of Computer-Mediated Communication and Face-to-Face Communication

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    The objective of the research was to explore and compare the differences in potential creative thinking that media richness had on learners in creativity training through two different types of communication formats; computer-mediated communication, and face-to-face communication. The results indicated that the computer-mediated communication format performed better than the face-to-face in terms of the fluency, flexibility, and originality dimensions of creative thinking. The computer-mediated communication format also had a greater level of media richness perception (i.e., use of multiple cues, language diversity, and personal focus of the medium) than the face-to-face format. In terms of the combined effectiveness of computer-mediated communication, and face-to-face formats, the use of multiple cues, language variety of perception of media richness had direct effects on the fluency of creativity. There was also a positive correlation between the elaboration of creativity and the use of multiple cues, language variety, and personal focus of the medium in the perception of media richness. Furthermore, language variety was correlated with creativity and flexibility. The research findings highlighted the importance of the availability of immediate feedback on media richness, whereas creativity cognition should focus on the breadth and depth of the information, which contributes to enhancing the creativity of individuals or a group of employees

    Cyclooxygenase-2 enhances α2β1 integrin expression and cell migration via EP1 dependent signaling pathway in human chondrosarcoma cells

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    <p>Abstract</p> <p>Background</p> <p>Cyclooxygenase (COX)-2, the inducible isoform of prostaglandin (PG) synthase, has been implicated in tumor metastasis. Interaction of COX-2 with its specific EP receptors on the surface of cancer cells has been reported to induce cancer invasion. However, the effects of COX-2 on migration activity in human chondrosarcoma cells are mostly unknown. In this study, we examined whether COX-2 and EP interaction are involved in metastasis of human chondrosarcoma.</p> <p>Results</p> <p>We found that over-expression of COX-2 or exogenous PGE<sub>2 </sub>increased the migration of human chondrosarcoma cells. We also found that human chondrosarcoma tissues and chondrosarcoma cell lines had significant expression of the COX-2 which was higher than that in normal cartilage. By using pharmacological inhibitors or activators or genetic inhibition by the EP receptors, we discovered that the EP1 receptor but not other PGE receptors is involved in PGE<sub>2</sub>-mediated cell migration and α2β1 integrin expression. Furthermore, we found that human chondrosarcoma tissues expressed a higher level of EP1 receptor than normal cartilage. PGE<sub>2</sub>-mediated migration and integrin up-regulation were attenuated by phospholipase C (PLC), protein kinase C (PKC) and c-Src inhibitor. Activation of the PLCβ, PKCα, c-Src and NF-κB signaling pathway after PGE<sub>2 </sub>treatment was demonstrated, and PGE<sub>2</sub>-induced expression of integrin and migration activity were inhibited by the specific inhibitor, siRNA and mutants of PLC, PKC, c-Src and NF-κB cascades.</p> <p>Conclusions</p> <p>Our results indicated that PGE<sub>2 </sub>enhances the migration of chondrosarcoma cells by increasing α2β1 integrin expression through the EP1/PLC/PKCα/c-Src/NF-κB signal transduction pathway.</p
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