4,946 research outputs found
Tailoring excitonic states of van der Waals bilayers through stacking configuration, band alignment and valley-spin
Excitons in monolayer semiconductors have large optical transition dipole for
strong coupling with light field. Interlayer excitons in heterobilayers, with
layer separation of electron and hole components, feature large electric dipole
that enables strong coupling with electric field and exciton-exciton
interaction, at the cost that the optical dipole is substantially quenched (by
several orders of magnitude). In this letter, we demonstrate the ability to
create a new class of excitons in transition metal dichalcogenide (TMD) hetero-
and homo-bilayers that combines the advantages of monolayer- and
interlayer-excitons, i.e. featuring both large optical dipole and large
electric dipole. These excitons consist of an electron that is well confined in
an individual layer, and a hole that is well extended in both layers, realized
here through the carrier-species specific layer-hybridization controlled
through the interplay of rotational, translational, band offset, and
valley-spin degrees of freedom. We observe different species of such
layer-hybridized valley excitons in different heterobilayer and homobilayer
systems, which can be utilized for realizing strongly interacting
excitonic/polaritonic gases, as well as optical quantum coherent controls of
bidirectional interlayer carrier transfer either with upper conversion or down
conversion in energy
Assessing Climate Change Impact on Gilgel Abbay and Gumara Watershed Hydrology, the Upper Blue Nile Basin, Ethiopia
Climate change and variability have significant influences on hydrological cycles and the availability of water in the Horn of Africa. Projections of six General Circulation Models (GCMs) in association with high (A2) and low (B1) emission scenarios were adopted in this study from the Special Report on Emission Scenarios (SRES) for the period 2020 - 2039 to assess the impacts of climate changes on the Gilgel Abbay and Gumara watershed hydrology, the upper Blue Nile basin, Ethiopia. The GCMs selected were screened in accordance with baseline climate statistics of study areas. A weather generator was employed to generate daily temperature and precipitation to drive the General Water Loading Function (GWLF) hydrological model for simulating runoffs. Projected changes in temperature differences and precipitation ratios relative to the baseline were analyzed to explain the variations in evapotranspiration and the influences on runoff. Despite the fact that the projected magnitude varies among GCMs, increasing runoff in both wet and dry seasons was observed for both watersheds, attributable mainly to the increase in precipitation projected by most GCMs. In contrast to the great increases in runoff, variations in evapotranspiration are less significant. The projected runoff in both watersheds implies increased potential for promoting agricultural irrigation in the dry season. Furthermore, it would allow greater inflow to Lake Tana, the largest contributor to the Ethiopian Renaissance Dam on the Blue Nile. Therefore, concerned local, state, and federal government organizations shall be prepared to harness opportunities from the projected increase in runoff
Nemonoxacin (Taigexyn<sup>Ā®</sup>): A New Non-Fluorinated Quinolone
Nemonoxacin (TaigexynĀ®), a novel C-8-methoxy non-fluorinated quinolone, has been approved for use in community-acquired pneumonia (CAP) in Taiwan (2014) and mainland China (2016). The FDA granted nemonoxacin āqualified infectious disease productā and āfast-trackā designations for CAP and acute bacterial skin and skin structure infection in December 2013. It possesses a broad spectrum of bactericidal activity against typical and atypical respiratory pathogens. In particular, nemonoxacin has activity against resistant Gram-positive cocci, including penicillin-resistant Streptococcus pneumoniae and methicillin-resistant Staphylococcus aureus. Oral nemonoxacin was compared with oral levofloxacin for efficacy and safety in three randomized, double-blinded, controlled Phase IIāIII clinical trials for the treatment of CAP.Ā This article will review the microbiological profile of nemonoxacin against respiratory pathogens including S. pneumoniae and S. aureus, and microbiological outcome data from the three Phase IIāIII studies
Voxel-based analysis of apparent diffusion coefficient in perihaematomal oedema: associated factors and outcome predictive value for intracerebral haemorrhage
Differential cellular responses to FDA-approved nanomedicines:an exploration of albumin-based nanocarriers and liposomes in protein corona formation
Assessing water resources vulnerability and resilience of southern Taiwan to climate change
Water resources management has become more challenging in Taiwan due to rapid socio-economic development and the complications of climate change. This study developed a systematic procedure for assessing water resources vulnerability and resilience with an integrated tool, TaiWAP, including climate change scenarios, a weather generator, a hydrological model, and system dynamic models. Five assessment indicators, including two for vulnerability, two for resilience, and one for availability were used to quantify changes in water resources and improvements after implementing adaption measures. Each indicator was presented with 3 grades, namely low, medium, and high. Water resources vulnerability and resilience for Tainan City in southern Taiwan were evaluated. Insufficient water supply facilities capacity is the major weakness causing low resilience. Water resources allocation flexibility is limited by substantial agricultural water demands. A total of 9 adaption measures and combinations of measures were assessed. Desalination plant implementation can steadily supply public water to lessen system failure duration. Although agricultural water conservation and fallow land can greatly reduce water demand, fallow compensation is a potential cost. When food security is considered, reducing irrigation leakage will be a better adaption measure to both water and agriculture stakeholders. Both agriculture water conservation and cropping systems adjustment have cross-spatial flexibilities. The combination of desalination, reservoirs and public water conservation provide the most beneficial effects in reducing climate change impact
- ā¦