Psychological aspects of sports injuries among male professional soccer players in croatia

The aim of this study was to assess occurrence of sports injuries among professional male soccer players in relation to their psychological characteristics. This prospective cohort study was conducted during the 2013/2014 sports season among all professional players with the first team contract in the first Croatian soccer league. A stratified sample of 182 male soccer players were selected for the assessment. They were surveyed during their preparation period before the beginning of the season and were under monitoring during the season. Seriousness of injuries was assessed depending on the length (one day or more) of players’ non-participation in sports activities. Psychological characteristics were assessed by the General Anxiety Disorder Scale (GAD-7), Revised Center for Epidemiologic Studies Depression Scale, impulsive behaviour scale from the Zuckerman-Kuhlman Personality Questionnaire Cross-Cultural 50-item version and Psychological Skills Inventory for Sports. Majority of players (62.6%) experienced a kind of injury, with the mean number of 1.28 injuries per player, and 30.7% of them contracted severe injuries. Results of the binary regression model suggest that likelihood of being injured is mostly influenced by higher Impulsive Sensation Seeking and GAD-7 scores (OR=1.26 in both cases). In contrast, adequate mental preparation significantly lowers the chance of being injured (OR=0.89).The study adds an insight into proportions, severity, mechanisms and number of sport injuries in the population of Croatian professional soccer players. We propose several variables as important predictors of future injuries. Some scales, commonly used in this field, have been shown to be less useful in injury prediction

COVID-19 i dijagnostika tumora prostate u KBC-u Zagreb

The aim of this study was to compare the number of biopsy and surgical procedures on prostate, as well as the number of newly diagnosed, histologically confirmed cases of prostate cancer during the COVID-19 pandemic at Zagreb University Hospital Center (UHC). We retrospectively collected and processed a total of 1344 histopathologic findings of the prostate at the Zagreb UHC. Our results show that during the COVID-19 pandemic, there was a statistically significant decrease in the absolute number of biopsy and surgical procedures on prostate at Zagreb UHC, and so was the number of newly diagnosed, histologically confirmed cases of prostate cancer. During the observed time of the pandemic (March 19, 2020 to December 31, 2020), there was a 37.5% decrease in the absolute number of newly diagnosed prostate cancer cases compared to the same period of the previous year (March 19, 2019 to December 31, 2019). To our knowledge, this is the first study of this kind that is based on the number of prostate cancer diagnoses in Croatia. By observing the early period of the pandemic, our results provide important guidelines for monitoring and understanding the long-term consequences of the pandemic on the prostate cancer morbidity and mortality.Cilj ovoga istraživanja bio je usporediti broj biopsijskih i kirurških zahvata na prostati, kao i broj novodijagnosticiranih, patohistološki potvrđenih slučajeva karcinoma prostate tijekom pandemije COVID-19 u Kliničkom bolničkom centru Zagreb. Retrogradno smo prikupili i obradili ukupno 1344 patohistoloških nalaza prostate na Kliničkom zavodu za patologiju i citologiju KBC-a Zagreb. Naši rezultati pokazuju da je tijekom pandemije COVID-19 došlo do statistički značajnog pada apsolutnog broja biopsijskih i kirurških zahvata na prostati, kao i broja novodijagnosticiranih, patohistološki potvrđenih slučajeva karcinoma prostate. Uočen je pad apsolutnog broja novodijagnosticiranih karcinoma prostate za 37,5% u promatranom vremenu pandemije (od 19. ožujka do 31. prosinca 2020. godine) u odnosu na isto razdoblje u prethodnoj godini (od 19. ožujka do 31. prosinca 2019. godine). Prema našim spoznajama ovo je prvo istraživanje ovakvog tipa temeljeno na broju pretraga karcinoma prostate na području Republike Hrvatske. Promatrajući rano razdoblje pandemije naši rezultati donose važne smjernice u budućem praćenju i dugoročnim posljedicama pandemije na pobol i smrtnost karcinoma prostate

Changes in brain metabolites measured with magnetic resonance spectroscopy in antidepressant responders with comorbid major depression and posttraumatic stress disorder [Promjene razina moždanih metabolita mjerenih magnetskom rezonantnom spektroskopijom u ispitanika s komorbiditetom depresije i posttraumatskog stresnog poremećaja koji su odgovorili na antidepresivno liječenje]

In a present pilot study, performed on 11 subjects, we studied proton magnetic resonance spectroscopy (1H-MRS) changes in early to intermediate (3-6 weeks) responders to antidepressant treatment with selective serotonin reuptake inhibitors (SSRIs). All subjects had diagnosis of major recurrent depression comorbid to posttraumatic stress disorder (PTSD). Magnetic spectroscopy was done in the region of dorsolateral prefrontal cortex on a 3T MRI-unit. Participants were selected out of the larger sample due to an early response to antidepressant treatment within 3–6 weeks, measured with Beck Depression Inventory (BDI). We measured levels of neuronal marker N-acetyl-aspartate (NAA), choline (CHO) and creatine (Cr). There was no difference in NAA/Cr ratios between the first and the second spectroscopic scans (p=0.751). However, CHO/Cr ratios showed increasing trend with mean value at the first scan of 1.09 (SD=0.22) while mean value at second scan was 1.25 (SD=0.24), displaying statically significant difference (p=0.015). In conclusion, significant increase in choline to creatine ratio from the first to the second spectroscopic scan during the antidepressant treatment, compared to almost identical values of NAA to creatine ratio, suggests increased turnover of cell membranes as a mechanism of the early response to the antidepressant drug therapy

Utjecaj pandemije COVID-19 na novodijagnosticirane urotelne karcinome

The aim of this study was to compare the number of newly diagnosed, histopathologically confirmed cases of urothelial carcinoma before and during the COVID-19 pandemic at the Zagreb University Hospital Center. We retroactively collected and analyzed 300 histopathologically confirmed urothelial carcinoma between January 1, 2019, and December 31, 2020, at the Department of Pathology and Cytology, Zagreb University Hospital Center. Our results showed that during the COVID-19 pandemic, there was a statistically significant decrease (p=0.001; χ2-test) in the number of newly diagnosed, histopathologically confirmed cases of urothelial carcinoma at the Zagreb University Hospital Center. There was a decrease in the absolute number of newly diagnosed urothelial carcinoma by 25.8% in the observed time of the pandemic (March 19, 2020 to December 31, 2020) as compared to the same period of the previous year (March 19, 2019 to December 31, 2019). Our study is the first study of this type based on the number of newly diagnosed urothelial carcinoma in Croatia. Observing the early period of the pandemic, our results provide important foundation for future monitoring and long-term consequences of the pandemic on the morbidity and mortality of urothelial carcinoma.Cilj ovog istraživanja bio je usporediti broj novodijagnosticiranih, patohistološki potvrđenih slučajeva urotelnog karcinoma prije i tijekom pandemije COVID-19 u KBC-u Zagreb. Na Kliničkom zavodu za patologiju i citologiju KBC-a Zagreb retroaktivno smo prikupili i obradili ukupno 300 patohistološki potvrđenih urotelnih karcinoma. Naši rezultati pokazuju da je tijekom pandemije COVID-19 došlo do statistički značajnog smanjenja (p=0,001; χ2-test) broja novodijagnosticiranih, patohistološki potvrđenih slučajeva urotelnog karcinoma u KBC-u Zagreb. Uočen je pad apsolutnog broja novodijagnosticiranih urotelnih karcinoma za 25,8% u promatranom vremenu pandemije (19. ožujka 2020. do 31. prosinca 2020.) u odnosu na isto razdoblje prošle godine (19. ožujka 2019. do 31. prosinca 2019.). Prema našim saznanjima, ovo je prva studija ovog tipa temeljena na broju novodijagnosticiranih urotelnih karcinoma u Hrvatskoj. Promatrajući rano razdoblje pandemije, naši rezultati daju važne temelje za buduće praćenje i dugoročne posljedice pandemije na pobol i smrtnost od urotelnog karcinoma

FUNCTIONAL STATUS ASSESSMENT OF PATIENTS WITH LOWER LIMB AMPUTATION USING LOCOMOTOR CAPABILITIES INDEX QUESTIONNAIRE

Za procjenu funkcionalnog ishoda protetičke rehabilitacije bolesnika učestalo se koristi upitnik Indeks lokomotornih mogućnosti (engl. Locomotor Capabilities Index- LCI) koji je dio većeg upitnika PPA (engl. The Prosthetic profile of the Amputee Person questionnaire) specifičnog za osobe s amputacijom donjeg uda

COVID-19 i dijagnostika tumora prostate u KBC-u Zagreb

The aim of this study was to compare the number of biopsy and surgical procedures on prostate, as well as the number of newly diagnosed, histologically confirmed cases of prostate cancer during the COVID-19 pandemic at Zagreb University Hospital Center (UHC). We retrospectively collected and processed a total of 1344 histopathologic findings of the prostate at the Zagreb UHC. Our results show that during the COVID-19 pandemic, there was a statistically significant decrease in the absolute number of biopsy and surgical procedures on prostate at Zagreb UHC, and so was the number of newly diagnosed, histologically confirmed cases of prostate cancer. During the observed time of the pandemic (March 19, 2020 to December 31, 2020), there was a 37.5% decrease in the absolute number of newly diagnosed prostate cancer cases compared to the same period of the previous year (March 19, 2019 to December 31, 2019). To our knowledge, this is the first study of this kind that is based on the number of prostate cancer diagnoses in Croatia. By observing the early period of the pandemic, our results provide important guidelines for monitoring and understanding the long-term consequences of the pandemic on the prostate cancer morbidity and mortality.Cilj ovoga istraživanja bio je usporediti broj biopsijskih i kirurških zahvata na prostati, kao i broj novodijagnosticiranih, patohistološki potvrđenih slučajeva karcinoma prostate tijekom pandemije COVID-19 u Kliničkom bolničkom centru Zagreb. Retrogradno smo prikupili i obradili ukupno 1344 patohistoloških nalaza prostate na Kliničkom zavodu za patologiju i citologiju KBC-a Zagreb. Naši rezultati pokazuju da je tijekom pandemije COVID-19 došlo do statistički značajnog pada apsolutnog broja biopsijskih i kirurških zahvata na prostati, kao i broja novodijagnosticiranih, patohistološki potvrđenih slučajeva karcinoma prostate. Uočen je pad apsolutnog broja novodijagnosticiranih karcinoma prostate za 37,5% u promatranom vremenu pandemije (od 19. ožujka do 31. prosinca 2020. godine) u odnosu na isto razdoblje u prethodnoj godini (od 19. ožujka do 31. prosinca 2019. godine). Prema našim spoznajama ovo je prvo istraživanje ovakvog tipa temeljeno na broju pretraga karcinoma prostate na području Republike Hrvatske. Promatrajući rano razdoblje pandemije naši rezultati donose važne smjernice u budućem praćenju i dugoročnim posljedicama pandemije na pobol i smrtnost karcinoma prostate