New routes to nitride materials : oxide precursors and nitrogen plasmas

Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Chemistry, 1996.Includes bibliographical references.by Joel David Houmes.Ph.D

Hemodynamic effects of partial liquid ventilation with perfluorocarbon in acute lung injury

Objective: To assess the effect of partial liquid ventilation with perfluorocarbons on hemodynamics and gas exchange in large pigs with induced acute lung injury (ALI). Design: Randomized, prospective, double-control, experimental study. Setting: Experimental intensive care unit of a university. Materials: Eighteen large pigs (50±5 kg body weight) with an average anterior posterior thoracic diameter of 24 cm and induced acute lung injury. Interventions: All animals were surfactant depleted by lung lavage to a PaO2 below 100 mmHg and randomized to receive either perflubron (n=6) or saline (n=6) in five intratracheal doses of 5 ml/kg at 20-min intervals, or no instillation (n=6). Measurements and results: In all animals heart rate, arterial pressures, pulmonary pressures, cardiac output and blood gases were recorded at 20-min intervals. There was no deleterious effect on any hemodynamic parameter in the perflubron group, whereas systolic and mean pulmonary arterial pressure values showed a persistent decrease after the first 5 ml/kg of perflubron, from 48.7±14.1 to 40.8±11.7 mmHg and from 39.7±13.2 to 35.2±12.0 mmHg, respectively. Perflubron resulted in a significant (ANOVA P<0.01), dose-dependent increase in PaO2 values from 86.3±22.4 to a maximum of 342.4±59.4 mmHg at a dose of 25 ml/kg; the other groups showed no significant increase in PaO2. Conclusions: Tracheal instillation of perflubron in induced ALI results in a dose-dependent increase in PaO2 and has no deleterious effect on hemodynamic parameters

Model Pratice Building: Baseline Evaluation Findings

This report presents the key findings based on data from baseline qualitative interviews and retrospective data collected from December 2007 to September 2009. The evaluation found grantees reported much success implementing their project. In particular, increasing project visibility and buy-in within their communities were areas where grantees felt they made significant progress.https://openscholarship.wustl.edu/cphss/1050/thumbnail.jp

St. Louis County CPPW Evaluation Final Report

This report presents final evaluation results from the Communities Putting Prevention to Work (CPPW) Initiative, implemented from February 2010 through June 2012. The final results show CPPW partners implemented a number of activities to achieve the main objectives of the Initiative. In particular, advocacy and policy change, cessation, and media outreach were important areas of focus.https://openscholarship.wustl.edu/cphss/1055/thumbnail.jp

Invasive ventilation modes in children: a systematic review and meta-analysis

Introduction: The purpose of the present study was to critically review the existing body of evidence on ventilation modes for infants and children up to the age of 18 years.Methods: The PubMed and EMBASE databases were searched using the search terms 'artificial respiration', 'instrumentation', 'device', 'devices', 'mode', and 'modes'. The review included only studies comparing two ventilation modes in a randomized controlled study and reporting one of the following outcome measures: length of ventilation (LOV), oxygenation, mortality, chronic lung disease and weaning. We quantitatively pooled the results of trials where suitable.Results: Five trials met the inclusion criteria. They addressed six different ventilation modes in 421 children: high-frequency oscillation (HFO), pressure control (PC), pressure support (PS), volume support (VS), volume diffusive respirator (VDR) and biphasic positive airway pr

Contesting Corporate Control in the U.S.: The Role of Ownership Structure and the Anti-takeover Measure

This study investigates the role of ownership structure and anti-takeover measure in proxy contests using the nested logistic model. Findings indicate that dissidents target small firms with high agency costs, poor performance, and a high volume of prior shareholder proposals for Media Threats. Following a Media Threat, dissidents target firms with more independent boards, with the next step being a SEC filing of a proxy fight. After that, management in firms with "poison pills" and less independent boards are more likely to settle contests with dissidents, while firms with lower insider ownership are more likely to go through a proxy fight

Contesting Corporate Control in the U.S.: The Role of Ownership Structure and the Anti-takeover Measure

This study investigates the role of ownership structure and anti-takeover measure in proxy contests using the nested logistic model. Findings indicate that dissidents target small firms with high agency costs, poor performance, and a high volume of prior shareholder proposals for Media Threats. Following a Media Threat, dissidents target firms with more independent boards, with the next step being a SEC filing of a proxy fight. After that, management in firms with "poison pills" and less independent boards are more likely to settle contests with dissidents, while firms with lower insider ownership are more likely to go through a proxy fight