258 research outputs found
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Notations and conventions in molecular spectroscopy: part 1. General spectroscopic notation
The field of Molecular Spectroscopy was surveyed in order to determine a set of
conventions and symbols which are in common use in the spectroscopic literature. This
document, which is Part I in a series, establishes the notations and conventions used for
general spectroscopic notations and deals with quantum mechanics, quantum numbers
(vibrational states, angular momentum and energy levels), spectroscopic transitions, and
miscellaneous notations (e.g. spectroscopic terms). Further parts will follow, dealing inter
alia with symmetry notation, permutation and permutation-inversion symmetry notation,
vibration-rotation spectroscopy and electronic spectroscopy
Recommended from our members
Notations and conventions in molecular spectroscopy: part 2. Symmetry notation
The field of Molecular Spectroscopy was surveyed in order to determine a set of
conventions and symbols which are in common use in the spectroscopic literature. This
document, which is Part 2 in a series, establishes the notations and conventions used for the
description of symmetry in rigid molecules, using the Schoenflies notation. It deals firstly
with the symmetry operators of the molecular point groups (also drawing attention to the
difference between symmetry operators and elements). The conventions and notations of the
molecular point groups are then established, followed by those of the representations of these
groups as used in molecular spectroscopy. Further parts will follow, dealing inter alia with
permutation and permutation-inversion symmetry notation, vibration-rotation spectroscopy
and electronic spectroscopy
Detection of interstellar hydrogen peroxide
The molecular species hydrogen peroxide, HOOH, is likely to be a key
ingredient in the oxygen and water chemistry in the interstellar medium. Our
aim with this investigation is to determine how abundant HOOH is in the cloud
core {\rho} Oph A. By observing several transitions of HOOH in the
(sub)millimeter regime we seek to identify the molecule and also to determine
the excitation conditions through a multilevel excitation analysis. We have
detected three spectral lines toward the SM1 position of {\rho} Oph A at
velocity-corrected frequencies that coincide very closely with those measured
from laboratory spectroscopy of HOOH. A fourth line was detected at the
4{\sigma} level. We also found through mapping observations that the HOOH
emission extends (about 0.05 pc) over the densest part of the {\rho} Oph A
cloud core. We derive an abundance of HOOH relative to that of H_2 in the SM1
core of about 1\times10^(-10). To our knowledge, this is the first reported
detection of HOOH in the interstellar medium.Comment: 5 pages, 4 figures, accepted for publication in Astronomy &
Astrophysics, new version corrects a typo in Table 1 (and consequently in Fig
4
Genetic determinants of co-accessible chromatin regions in activated T cells across humans.
Over 90% of genetic variants associated with complex human traits map to non-coding regions, but little is understood about how they modulate gene regulation in health and disease. One possible mechanism is that genetic variants affect the activity of one or more cis-regulatory elements leading to gene expression variation in specific cell types. To identify such cases, we analyzed ATAC-seq and RNA-seq profiles from stimulated primary CD4+ T cells in up to 105 healthy donors. We found that regions of accessible chromatin (ATAC-peaks) are co-accessible at kilobase and megabase resolution, consistent with the three-dimensional chromatin organization measured by in situ Hi-C in T cells. Fifteen percent of genetic variants located within ATAC-peaks affected the accessibility of the corresponding peak (local-ATAC-QTLs). Local-ATAC-QTLs have the largest effects on co-accessible peaks, are associated with gene expression and are enriched for autoimmune disease variants. Our results provide insights into how natural genetic variants modulate cis-regulatory elements, in isolation or in concert, to influence gene expression
Complete Genome Sequence of Treponema paraluiscuniculi, Strain Cuniculi A: The Loss of Infectivity to Humans Is Associated with Genome Decay
Treponema paraluiscuniculi is the causative agent of rabbit venereal spirochetosis. It is not infectious to humans, although its genome structure is very closely related to other pathogenic Treponema species including Treponema pallidum subspecies pallidum, the etiological agent of syphilis. In this study, the genome sequence of Treponema paraluiscuniculi, strain Cuniculi A, was determined by a combination of several high-throughput sequencing strategies. Whereas the overall size (1,133,390 bp), arrangement, and gene content of the Cuniculi A genome closely resembled those of the T. pallidum genome, the T. paraluiscuniculi genome contained a markedly higher number of pseudogenes and gene fragments (51). In addition to pseudogenes, 33 divergent genes were also found in the T. paraluiscuniculi genome. A set of 32 (out of 84) affected genes encoded proteins of known or predicted function in the Nichols genome. These proteins included virulence factors, gene regulators and components of DNA repair and recombination. The majority (52 or 61.9%) of the Cuniculi A pseudogenes and divergent genes were of unknown function. Our results indicate that T. paraluiscuniculi has evolved from a T. pallidum-like ancestor and adapted to a specialized host-associated niche (rabbits) during loss of infectivity to humans. The genes that are inactivated or altered in T. paraluiscuniculi are candidates for virulence factors important in the infectivity and pathogenesis of T. pallidum subspecies
Terahertz Laser Vibration−Rotation Tunneling Spectroscopy and Dipole Moment of a Cage Form of the Water Hexamer
Physical and psychological sequelae to torture. A controlled clinical study of exiled asylum applicants
The athymic nude rat. Immunobiological characteristics with special reference to establishment of non-antigen-specific T-cell reactivity and induction of antigen-specific immunity
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