16,271 research outputs found
TBC1D3 promotes neural progenitor proliferation by suppressing the histone methyltransferase G9a
Two-component model for the chemical evolution of the Galactic disk
In the present paper, we introduce a two-component model of the Galactic disk
to investigate its chemical evolution. The formation of the thick and thin
disks occur in two main accretion episodes with both infall rates to be
Gaussian. Both the pre-thin and post-thin scenarios for the formation of the
Galactic disk are considered. The best-fitting is obtained through
-test between the models and the new observed metallicity distribution
function of G dwarfs in the solar neighbourhood (Hou et al 1998). Our results
show that post-thin disk scenario for the formation of the Galactic disk should
be preferred. Still, other comparison between model predictions and
observations are given.Comment: 23 pages, 7 figure
Fermi resonance-algebraic model for molecular vibrational spectra
A Fermi resonance-algebraic model is proposed for molecular vibrations, where
a U(2) algebra is used for describing the vibrations of each bond, and Fermi
resonances between stretching and bending modes are taken into account. The
model for a bent molecule XY_2 and a molecule XY_3 is successfully applied to
fit the recently observed vibrational spectrum of the water molecule and arsine
(AsH_3), respectively, and results are compared with those of other models.
Calculations show that algebraic approaches can be used as an effective method
for describing molecular vibrations with small standard deviations
Noncontact Operation-State Monitoring Technology Based on Magnetic-Field Sensing for Overhead High-Voltage Transmission Lines
published_or_final_versio
Efficacy of osmoprotectants on prevention and treatment of murine dry eye
Purpose: To evaluate the efficacy of osmoprotectants on prevention and treatment of dry eye in a murine model.
Methods: Dry eye was induced in mice by using an intelligently controlled environmental system (ICES). Osmoprotectants betaine, L-carnitine, erythritol, or vehicle (PBS) were topically administered to eyes four times daily following two schedules: schedule 1 (modeling prevention): dosing started at the beginning of housing in ICES and lasted for 21 or 35 days; schedule 2 (modeling treatment): dosing started after ICES-housed mice developed dry eye (day 21), continuing until day 35. Treatment efficacy was evaluated for corneal fluorescein staining; corneal epithelial apoptosis by TUNEL and caspase-3 assays; goblet cell numbers by PAS staining; and expression of inflammatory mediators, TNF-a, IL-17, IL-6, or IL-1b by using RT-PCR on days 0, 14, 21, and/or 35.
Results: Compared with vehicle, prophylactic administration of betaine, L-carnitine, or erythritol significantly decreased corneal staining and expression of TNF-a and IL-17 on day 21 (schedule 1). Treatment of mouse dry eye with osmoprotectants significantly reduced corneal staining on day 35 compared with day 21 (schedule 2). Relative to vehicle, L-carnitine treatment of mouse dry eye for 14 days (days 21 to 35) resulted in a significant reduction in corneal staining, number of TUNEL-positive cells, and expression of TNF-a, IL-17, IL-6, or IL- 1b, as well as significantly increased the number of goblet cells.
Conclusion: Topical application of betaine, L-carnitine, or erythritol systematically limited progression of environmentally induced dry eye. L-carnitine can also reduce the severity of such dry-eye conditions
Necessary and sufficient conditions for local creation of quantum discord
We show that a local channel cannot create quantum discord (QD) for zero QD
states of size if and only if either it is a completely decohering
channel or it is a nontrivial isotropic channel. For the qubit case this
propertiy is additionally characteristic to the completely decohering channel
or the commutativity-preserving unital channel. In particular, the exact forms
of the completely decohering channel and the commutativity-preserving unital
qubit channel are proposed. Consequently, our results confirm and improve the
conjecture proposed by X. Hu et al. for the case of and improve the
result proposed by A. Streltsov et al. for the qubit case. Furthermore, it is
shown that a local channel nullifies QD in any state if and only if it is a
completely decohering channel. Based on our results, some protocols of quantum
information processing issues associated with QD, especially for the qubit
case, would be experimentally accessible.Comment: 8 page
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