13 research outputs found
Hypertonic saline and recombinant human DNase: a randomised cross-over pilot study in patients with cystic fibrosis
Phosphatidylcholine metabolism of rat trachea in relation to lung parenchyma and surfactant
Long-Term Azithromycin Therapy in Cystic Fibrosis Patients: A Study on Drug Levels and Sputum Properties
BACKGROUND: Following reports on the treatment of diffuse panbronchiolitis (DPB), recent studies demonstrate that long term therapy with azithromycin (AZM) is effective in cystic fibrosis (CF) patients. However, the underlying mechanisms remain uncertain. Some macrolides, including AZM, display inhibition of virulence factors and other antipseudomonal effects at subinhibitory levels in vitro