45 research outputs found

    Additions to the Last Millennium Reanalysis Multi-Proxy Database

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    Progress in paleoclimatology increasingly occurs via data syntheses. We describe additions to a collection prepared for use in paleoclimate state estimation, specifically the Last Millennium Reanalysis (LMR). The 2290 additional series include 2152 tree ring chronologies and 138 other series. They supplement the collection used previously and together form a database titled LMRdb 1.0.0. The additional data draws from lake core, ice core, coral, speleothem, and tree ring archives, using published data primarily from the NOAA Paleoclimatology archive and a set of tree ring width chronologies standardized from raw International Tree Ring Data Bank ring width series. In contrast to many previous paleo compilations, the data were not selected (screened) on the basis of their environmental correlation, multi-century length, or other attributes. The inclusion of proxies sensitive to moisture and other environmental variables expands their use in data assimilation. A preliminary calibration using linear regression with mean annual temperature reveals characteristics of the proxy series and their relationship to temperature, as well as the noise and error characteristics of the records. The additional records are structured as individual files in the NOAA Paleoclimatology format and archived at NOAA Paleoclimatology (Anderson et al. 2018) and will continue to be improved and expanded as part of the LMR Project. The additions represent a four-fold increase in the number of records available for assimilation, provide expanded geographic coverage, and add additional proxy variables. Applications include data assimilation, proxy system model development, and paleoclimate reconstruction using climate field reconstruction and other methods

    Validation of Quantitative 3-Dimensional Transesophageal Echocardiography Mitral Valve Analysis Using Stereoscopic Display

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    OBJECTIVE The use of 3-dimensional (3D) transesophageal echocardiography (TEE) in perioperative evaluation of the mitral valve (MV) is increasing progressively, including the use of 3D MV models for quantitative analysis. However, the use of 3D MV models in clinical practice still is limited by the need for specific training and the long time required for analysis. A new stereoscopic visualization tool (EchoPixel True 3D) allows virtual examination of anatomic structures in the clinical setting, but its accuracy and feasibility for intraoperative use is unknown. The aim of this study was to assess the feasibility of 3D holographic display and evaluate 3D quantitative measurements on a volumetric MV image using the EchoPixel system compared with the 3D MV model generated by QLAB Mitral Valve Navigation (MVN) software. DESIGN This was a retrospective comparative study. SETTING The study took place in a tertiary care center. PARTICIPANTS A total of 40 patients, 20 with severe mitral regurgitation who underwent mitral valve repair and 20 controls with normal MV, were enrolled retrospectively. INTERVENTIONS The 3D-TEE datasets of the MV were analyzed using a 3D MV model and stereoscopic display. The agreement of measurements, intraobserver and interobserver variability, and time for analysis were assessed. MEASUREMENTS AND MAIN RESULTS Fair agreement between the 2 software systems was found for annular circumference and area in pathologic valves, but good agreement was reported for prolapse height and linear annular diameters. A higher agreement for all annular parameters and prolapse height was seen in normal valves. Excellent intraobserver and interobserver reliability was proved for the same parameters; time for analysis between the 2 methods in pathologic valves was substantially equivalent, although longer in pathologic valves when compared with normal MV using both tools. CONCLUSION EchoPixel proved to be reliable to display 3D TEE datasets and accurate for direct linear measurement of both MV annular sizes and prolapse height compared to QLAB MVN software; it also carries a low interobserver and intraobserver variability for most measurements

    Spontaneous Thrombosis of a Left Circumflex Artery Fistula Draining Into the Coronary Sinus

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    A 28-year-old woman was referred to our institution with sudden onset chest pain at rest. Electrocardiography revealed an inferoposterior ST-segment elevation myocardial infraction. The patient proceeded to cardiac catheterization, which revealed a large ectatic left circumflex coronary artery with an apparent fistula connecting it to the coronary sinus. Follow-up angiography revealed that the fistula was no longer patent, spontaneously thrombosed, and resolved without requiring surgery.</p

    Complex Interventions in the Adult with Congenital Heart Disease. Percutaneous Solutions for Venous Baffles, Coronary Artery Fistulas, and Ruptured Sinus of Valsalva Aneurysms.

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    We describe 3 distinct ACHD lesions amenable to percutaneous repair: (1) venous baffle obstruction in transposition of the great arteries, (2) coronary artery fistulas, and (3) ruptured sinus of Valsalva aneurysms. For each entity, we chronicle the typical clinical scenario and indications for intervention to supplement the technical approach and potential pitfalls with treatment. © 2013 Elsevier Inc
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