20 research outputs found
Reticulocyte hemoglobin equivalent (Ret He) and assessment of iron-deficient states
Direct measurement of the reticulocyte hemoglobin content provides useful information for the diagnosis and treatment of iron-deficient states. We have examined direct measurements of reticulocyte and red cell hemoglobin content on the Sysmex XE 2100 (Ret He and RBC He respectively) and the Bayer ADVIA 2120 (CHr and CH respectively) analyzers. Good agreement was found between Ret He and CHr (Y = 1.04X ā 1.06; r(2) = 0.88) and between the RBC He and CH parameters (Y = 0.93X + 1; r(2) = 0.84 n = 200) in pediatric patients and in normal adults (Ret He and CHr; Y = 1.06X ā 0.43; r(2) = 0.83; n = 126; RBC He and CH; Y = 0.94X + 1; r(2) = 0.87; n = 126). In 1500 blood samples from patients on chronic dialysis, Ret He was compared with traditional parameters for iron deficiency (serum iron <40 Ī¼g/dl, Tsat <20%, ferritin <100 ng/ml, hemoglobin <11 g/dl) for identifying iron-deficient states. Receiver operator characteristic (ROC) curve analysis revealed values of the area under the curve for Ret He of 0.913 (P < 0.0001). With a Ret He cutoff level of 27.2 pg, iron deficiency could be diagnosed with a sensitivity of 93.3%, and a specificity of 83.2%. Ret He is a reliable marker of cellular hemoglobin content and can be used to identify the presence of iron-deficient states
A Comparison of Quality of Life in Haemodialysis and Peritoneal Dialysis Patients
Decreased quality of life of end-stage renal disease is further compromised
by renal function replacement treatments such as haemodialysis (HD) and
peritoneal dialysis (PD). Poor quality of life negatively affects treatment
outcome. This study compared quality of life between HD and PD patients.
Quality of life in 15 HD and 15 PD patients at a South African renal unit was
compared using the SF-36 short form. There was no significant difference
between HD and PD patients for total SF-36 score, but HD subjects reported
more pain. Quality of life is similar in HD and PD patients, with the exception
of higher pain levels in HD patients