The gaps between the new EU legislation on in vitro diagnostics and the on-the-ground reality.

The background to this debate is now well-known: an EU policy decision to tighten controls on the devices and diagnostics sector led to the adoption of a regulation in 2017 with a schedule for implementation over coming years - a timetable extended still further by last-minute legislation in early 2022, to provide the sector and regulators with more time to adapt to the changes. Discussions among experts organised in April by the European Alliance for Personalized Medicine (EAPM) exposed continuing challenges that cannot be fully resolved by the recent deferral of implementation deadlines. One salient problem is that there is little awareness of the In Vitro Diagnostic Regulation (IVDR) across Europe, and only limited awareness of the different structures of national systems involved in implementing IVDR, with consequent risks for patient and consumer access to in vitro diagnostics (IVDs). The tentative conclusion from these consultations is that despite a will across the sector to seek workable solutions, the obstacles remain formidable, and the potential solutions so far proposed remain more a matter of aspirations than of clear pathways

CASPER coupled air-sea processes and electromagnetic ducting research

The Coupled Air\u2013Sea Processes and Electromagnetic Ducting Research (CASPER) project aims to better quantify atmospheric effects on the propagation of radar and communication signals in the marine environment. Such effects are associated with vertical gradients of temperature and water vapor in the marine atmospheric surface layer (MASL) and in the capping inversion of the marine atmospheric boundary layer (MABL), as well as the horizontal variations of these vertical gradients. CASPER field measurements emphasized simultaneous characterization of electromagnetic (EM) wave propagation, the propagation environment, and the physical processes that gave rise to the measured refractivity conditions. CASPER modeling efforts utilized state-of-the-art large-eddy simulations (LESs) with a dynamically coupled MASL and phase-resolved ocean surface waves. CASPER-East was the first of two planned field campaigns, conducted in October and November 2015 offshore of Duck, North Carolina. This article highlights the scientific motivations and objectives of CASPER and provides an overview of the CASPER-East field campaign. The CASPER-East sampling strategy enabled us to obtain EM wave propagation loss as well as concurrent environmental refractive conditions along the propagation path. This article highlights the initial results from this sampling strategy showing the range-dependent propagation loss, the atmospheric and upper-oceanic variability along the propagation range, and the MASL thermodynamic profiles measured during CASPER-East