New ⁴⁰Ar/³⁹Ar dating of the Grande Ronde lavas, Columbia River Basalts, USA: Implications for duration of flood basalt eruption episodes

Grande Ronde Basalt (GRB) lavas represent the most voluminous eruptive pulse of the Columbia River-Snake River-Yellowstone hotspot volcanism. With an estimated eruptive volume of 150,000 km3, GRB lavas form at least 66% of the total volume of the Columbia River Basalt Group. New 40Ar/39Ar dates for GRB lavas reveal they were emplaced within a maximum period of 0.42 ± 0.18 My. A well-documented stratigraphy indicates at least 110 GRB flow fields (or individual eruptions), and on this basis suggests an average inter-eruption hiatus of less than 4,000 years. Isotopic age-dating cannot resolve time gaps between GRB eruptions, and it is difficult to otherwise form a picture of the durations of eruptions because of non-uniform weathering in the top of flow fields and a general paucity of sediments between GR lavas. Where sediment has formed on top of the GRB, it varies in thickness from zero to 20-30 cm of silty to fine-sandy material, with occasional diatomaceous sediment. Individual GRB eruptions varied considerably in volume but many were greater than 1000 km3 in size. Most probably eruptive events were not equally spaced in time; some eruptions may have followed short periods of volcanic repose (perhaps 102 to 103 of yrs), whilst others could have been considerably longer (many 1000 s to > 104 yrs). Recent improvements in age-dating for other continental flood basalt (CFB) lava sequences have yielded estimates of total eruptive durations of less than 1 My for high-volume pulses of lava production. The GRB appears to be a similar example, where the main pulse occupied a brief period. Even allowing for moderate to long-duration pahoehoe flow field production, the amount of time the system spends in active lava-producing mode is small – less than c. 2.6% (based on eruption durations of approximately 10,000 yrs, as compared to the duration of the entire eruptive pulse of c. 420,000 yrs). A review of available 40Ar/39Ar data for the major voluminous phases of the Columbia River Basalt Group suggests that activity of the Steens Basalt-Imnaha Basalt-GRB may have, at times, been simultaneous, with obvious implications for climatic effects. Resolving intervals between successive eruptions during CFB province construction, and durations of main eruptive pulses, remains vital to determining the environmental impact of these huge eruptions

Probing Exotic Physics With Cosmic Neutrinos

Traditionally, collider experiments have been the primary tool used in searching for particle physics beyond the Standard Model. In this talk, I will discuss alternative approaches for exploring exotic physics scenarios using high energy and ultra-high energy cosmic neutrinos. Such neutrinos can be used to study interactions at energies higher, and over baselines longer, than those accessible to colliders. In this way, neutrino astronomy can provide a window into fundamental physics which is highly complementary to collider techniques. I will discuss the role of neutrino astronomy in fundamental physics, considering the use of such techniques in studying several specific scenarios including low scale gravity models, Standard Model electroweak instanton induced interactions, decaying neutrinos and quantum decoherence.Comment: 11 pages, 6 figures; For the proceedings of From Colliders To Cosmic Rays, Prague, Czech Republic, September 7-13, 200

Evidence Of Dark Matter Annihilations In The WMAP Haze

The WMAP experiment has revealed an excess of microwave emission from the region around the center of our Galaxy. It has been suggested that this signal, known as the ``WMAP Haze'', could be synchrotron emission from relativistic electrons and positrons generated in dark matter annihilations. In this letter, we revisit this possibility. We find that the angular distribution of the WMAP Haze matches the prediction for dark matter annihilations with a cusped density profile, $\rho(r) \propto r^{-1.2}$ in the inner kiloparsecs. Comparing the intensity in different WMAP frequency bands, we find that a wide range of possible WIMP annihilation modes are consistent with the spectrum of the haze for a WIMP with a mass in the 100 GeV to multi-TeV range. Most interestingly, we find that to generate the observed intensity of the haze, the dark matter annihilation cross section is required to be approximately equal to the value needed for a thermal relic, $\sigma v \sim 3 \times 10^{-26}$ cm$^3$/s. No boost factors are required. If dark matter annihilations are in fact responsible for the WMAP Haze, and the slope of the halo profile continues into the inner Galaxy, GLAST is expected to detect gamma rays from the dark matter annihilations in the Galactic Center if the WIMP mass is less than several hundred GeV.Comment: 4 pages, 3 figure

Kaluza-Klein Dark Matter, Electrons and Gamma Ray Telescopes

Kaluza-Klein dark matter particles can annihilate efficiently into electron-positron pairs, providing a discrete feature (a sharp edge) in the cosmic $e^+ e^-$ spectrum at an energy equal to the particle's mass (typically several hundred GeV to one TeV). Although this feature is probably beyond the reach of satellite or balloon-based cosmic ray experiments (those that distinguish the charge and mass of the primary particle), gamma ray telescopes may provide an alternative detection method. Designed to observe very high-energy gamma-rays, ACTs also observe the diffuse flux of electron-induced electromagnetic showers. The GLAST satellite, designed for gamma ray astronomy, will also observe any high energy showers (several hundred GeV and above) in its calorimeter. We show that high-significance detections of an electron-positron feature from Kaluza-Klein dark matter annihilations are possible with GLAST, and also with ACTs such as HESS, VERITAS or MAGIC.Comment: 10 pages, 2 figure

The Indirect Search for Dark Matter with IceCube

We revisit the prospects for IceCube and similar kilometer-scale telescopes to detect neutrinos produced by the annihilation of weakly interacting massive dark matter particles (WIMPs) in the Sun. We emphasize that the astrophysics of the problem is understood; models can be observed or, alternatively, ruled out. In searching for a WIMP with spin-independent interactions with ordinary matter, IceCube is only competitive with direct detection experiments if the WIMP mass is sufficiently large. For spin-dependent interactions IceCube already has improved the best limits on spin-dependent WIMP cross sections by two orders of magnitude. This is largely due to the fact that models with significant spin-dependent couplings to protons are the least constrained and, at the same time, the most promising because of the efficient capture of WIMPs in the Sun. We identify models where dark matter particles are beyond the reach of any planned direct detection experiments while being within reach of neutrino telescopes. In summary, we find that, even when contemplating recent direct detection results, neutrino telescopes have the opportunity to play an important as well as complementary role in the search for particle dark matter.Comment: 17 pages, 10 figures, published in the New Journal of Physics 11 105019 http://www.iop.org/EJ/abstract/1367-2630/11/10/105019, new version submitted to correct Abstract in origina

Endocrine therapy in prostate cancer: time for reappraisal of risks, benefits and cost-effectiveness?

In the 70 years following the first description of the benefits of surgical castration, despite advances in medical therapy e.g. cabazitaxel, enzalutamide, abiraterone, androgen deprivation therapy (ADT) remains the cornerstone of treatment for advanced prostate cancer. However, with increasing numbers of men undergoing PSA testing, the disease is being diagnosed earlier and the costs of ADT, with uncertain survival benefits and associated risks, have risen dramatically. Clinical studies of potent novel agents have shown survival benefits in advanced disease, but timing, risks and cost-effectiveness of treatment remain controversial. As new agents enter clinical practice, a comprehensive research strategy is essential to optimise benefits whilst minimising harm

Two photon annihilation of Kaluza-Klein dark matter

We investigate the fermionic one-loop cross section for the two photon annihilation of Kaluza-Klein (KK) dark matter particles in a model of universal extra dimensions (UED). This process gives a nearly mono-energetic gamma-ray line with energy equal to the KK dark matter particle mass. We find that the cross section is large enough that if a continuum signature is detected, the energy distribution of gamma-rays should end at the particle mass with a peak that is visible for an energy resolution of the detector at the percent level. This would give an unmistakable signature of a dark matter origin of the gamma-rays, and a unique determination of the dark matter particle mass, which in the case studied should be around 800 GeV. Unlike the situation for supersymmetric models where the two-gamma peak may or may not be visible depending on parameters, this feature seems to be quite robust in UED models, and should be similar in other models where annihilation into fermions is not helicity suppressed. The observability of the signal still depends on largely unknown astrophysical parameters related to the structure of the dark matter halo. If the dark matter near the galactic center is adiabatically contracted by the central star cluster, or if the dark matter halo has substructure surviving tidal effects, prospects for detection look promising.Comment: 17 pages, 3 figures; slightly revised versio

Limits on Supersymmetric Dark Matter From EGRET Observations of the Galactic Center Region

In most supersymmetic models, neutralino dark matter particles are predicted to accumulate in the Galactic center and annihilate generating, among other products, gamma rays. The EGRET experiment has made observations in this region, and is sensitive to gamma rays from 30 MeV to $\sim$30 GeV. We have used an improved point source analysis including an energy dependent point spread function and an unbinned maximum likelihood technique, which has allowed us to significantly lower the limits on gamma ray flux from the Galactic center. We find that the present EGRET data can limit many supersymmetric models if the density of the Galactic dark matter halo is cuspy or spiked toward the Galactic center. We also discuss the ability of GLAST to test these models.Comment: 4 pages, 3 figure