Status of 25-OH Vitamin D Serum Level among Wheezy Chronic Respiratory Diseases with Airway Obstructive Patterns; Office- Base Study

 Background: Vitamin D is a homeostasis hormone of the calcium and bone metabolism. It has additional effects in the infections, cardiovascular, immunity, anti- inflammatory, chronic respiratory diseases and small airway disease (SAD). Wheezing is the common clinical feature of small airway obstructive diseases. Prevalent of asthma and chronic obstructive pulmonary disease (COPD) are noticeable among SAD. Propose of the study assessed status of vitamin D level among wheezy chronic respiratory diseases with airway obstructive pattern. Methods: Sample population sequentially enrolled among office base- wheezy patients with chronic obstructive pattern. Vitamin D level was measured by ELISA. Results: We studied on 67 patients. Mean age was 42.9±1.5 SD years, ranged between 17-76 years. Their sex distribution was male 51% and female 49%. Vitamin D deficiency and insufficiency recorded 13% and 40%, respectively. Frequency of lower than set point value of vitamin D among subtypes of SAD was asthma, COPD and other subtypes of SAD, respectively. Conclusion: Outcome of the study disclosed relevant 25-OH vitamin D deficiency and insufficiency among wheezy respiratory diseases with airway obstructive pattern. COPD and asthma small airways were noticeable within population. Deficiency and insufficiency of vitamin D were considerable in female and male, respectively.