Distribution of the <i>MTHFR</i> genotypes among 266 childhood ALL patients and 266 controls.

<p>^a Based on Pearson’s chi-square test</p><p>^b OR: odds ratio; CI: confidence interval</p><p>* Statistically significant</p><p>Distribution of the <i>MTHFR</i> genotypes among 266 childhood ALL patients and 266 controls.</p

Demographic data of 266 childhood ALL patients and 266 controls.

<p>^a Based on a chi-square test.</p><p>Demographic data of 266 childhood ALL patients and 266 controls.</p

Distribution of the <i>MTHFR</i> C677T and A1298C genotypes stratified by age and gender

<p>^a<i>P</i> for trend based on chi-square test.</p><p>^b<i>P</i> for interaction based on likelihood ratio test; NS, non-significant.</p><p>^c OR, odds ratio; CI, confidence interval.</p><p>* Statistically significant.</p><p>Distribution of the <i>MTHFR</i> C677T and A1298C genotypes stratified by age and gender</p

Summary of the original international literature investigating the association of the <i>MTHFR</i> C677T genotypes with childhood leukemia.

<p>Note: Some studies that had less than 70 cases and 70 controls of a redundant population were not included.</p><p>The survey of literature was updated 2014/09/18.</p><p>Summary of the original international literature investigating the association of the <i>MTHFR</i> C677T genotypes with childhood leukemia.</p