62 research outputs found

    Additional file 1 of Identification of CD8+ T-cell exhaustion signatures for prognosis in HBV-related hepatocellular carcinoma patients by integrated analysis of single-cell and bulk RNA-sequencing

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    Additional file 1: Table S1. The primer sequences implemented in this study.Table S2. Number of different cell subtypes in various samples. Table S3. The relationship between the TEI and clinical characteristics in HCC patients

    Density Functional Theory Study of Controllable Optical Absorptions and Magneto-Optical Properties of Magnetic CrI<sub>3</sub> Nanoribbons: Implications for Compact 2D Magnetic Devices

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    A chromium triiodide (CrI3) monolayer has an interesting ferromagnetic ground state. In this work, we calculate band structures and magnetic moments of tensile-strained and bent zigzag CrI3 nanoribbons with density functional theory. The edge iodine atoms form flat low-lying conduction bands and couple with chromium atoms ferromagnetically, while the non-edge iodine atoms weakly couple antiferromagnetically. Narrow CrI3 nanoribbons have two locally stable magnetic moment orientations, namely, out-of-plane and in-plane (along the nanoribbon periodic direction) configurations. This enables four magnetization states in CrI3 nanoribbons, including two out-of-plane ones (up and down) and two in-plane ones (forward and backward along the nanoribbon periodical direction), increasing the operating controllability. Based on the one-dimensional Ising spin chain model, the spin correlation length of the narrow CrI3 nanoribbon is estimated to be about 10 Å at its estimated Curie temperature of 27 K, which is lower than the measured 45 K of the monolayer CrI3. The optical absorption and magneto-optical properties of CrI3 nanoribbons are investigated with many-body perturbation GW-BSE (Bethe–Salpeter equation), including magnetic dichroism and Faraday and magneto-optical Kerr effects. The low-energy dark excitons are mainly from transitions between electrons and holes with unlike spins and are non-Frenkel-like, while the bright excitons have mixed spin configurations. The intrinsic lifetime of excitons can be over one nanosecond, suitable for quantum information processes. Tensile strains and bending manifestly modulate the absorption spectra and magneto-optical properties of CrI3 nanoribbons within a technologically important photon energy range of ∼1.0–2.0 eV. The CrI3 nanoribbons can be used in 1D or 2D magnetic storage nanodevices, tunable magnetic optoelectronics, and spin-based quantum information controls

    Additional file 1: of Peroxisome Proliferators Activated Receptor (PPAR) agonists activate hepatitis B virus replication in vivo

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    Supplementary Figure 1. Alternation of HBV replicative intermediates in mouse livers after three PPAR agonists treatment. A. Alternation of HBV replicative intermediates in mouse livers after bezafibrate treatment at 30mg/kg.d and 60 mg/kg.d. B. Alternation of HBV replicative intermediates in mouse livers after fenofibrate treatment at 30mg/kg.d and 60 mg/kg.d. C. Alternation of HBV replicative intermediates in mouse livers after rosiglitazone treatment at 0.6mg/kg.d and 1.2 mg/kg.d. (DOCX 169 kb)

    sj-tif-1-evb-10.1177_11769343241249017 – Supplemental material for HNF4A-Bridging the Gap Between Intestinal Metaplasia and Gastric Cancer

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    Supplemental material, sj-tif-1-evb-10.1177_11769343241249017 for HNF4A-Bridging the Gap Between Intestinal Metaplasia and Gastric Cancer by Yihang Zhao, Hong Tang, Jianhua Xu, Feifei Sun, Yuanyuan Zhao and Yang Li in Evolutionary Bioinformatics</p

    Bioinspired Thermochromic Textile Based on Robust Cellulose Aerogel Fiber for Self-Adaptive Thermal Management and Dynamic Labels

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    Aerogel fiber has emerged recently for incorporation in personal thermal management textiles due to its flexibility, scalability, and ultrahigh porosity, which allows the body to keep warm via thermal isolation without energy consumption. However, the functionalization and intellectualization of cellulose-based aerogel fibers have not yet been fully developed. Herein, we propose a biomimicking design inspired by polar bear and Siamese cat hair that combines porous cellulose aerogel fiber (CAF) with reversible thermochromic microcapsules to mimic biological sensory and adaptive thermoregulation functions. The produced CAF has a controllable pore structure, a large specific surface area (230 m2/g), and excellent mechanical strength (∼15 MPa). Low-temperature darkening microcapsules have been incorporated into the robust CAF to spontaneously adjust color by perceiving the ambient temperature. The functional aerogel fiber fabric achieves high thermal insulation and photothermal modulation simultaneously at temperatures below 18 °C. The temperature of the thermochromic fabric was higher by 6 °C than that of the sample without the microcapsules at a light intensity of 0.2 W/cm2. In addition, the aerogel fibers mixed with two types of thermochromic microcapsules exhibit three color switches with fast response, a color-control precision of 0.2 °C, and good cycling performance. This smart aerogel fibers hold great promise for self-adaptive thermal management, temperature indication, information transfer, and anticounterfeiting in textiles

    Bioinspired Thermochromic Textile Based on Robust Cellulose Aerogel Fiber for Self-Adaptive Thermal Management and Dynamic Labels

    No full text
    Aerogel fiber has emerged recently for incorporation in personal thermal management textiles due to its flexibility, scalability, and ultrahigh porosity, which allows the body to keep warm via thermal isolation without energy consumption. However, the functionalization and intellectualization of cellulose-based aerogel fibers have not yet been fully developed. Herein, we propose a biomimicking design inspired by polar bear and Siamese cat hair that combines porous cellulose aerogel fiber (CAF) with reversible thermochromic microcapsules to mimic biological sensory and adaptive thermoregulation functions. The produced CAF has a controllable pore structure, a large specific surface area (230 m2/g), and excellent mechanical strength (∼15 MPa). Low-temperature darkening microcapsules have been incorporated into the robust CAF to spontaneously adjust color by perceiving the ambient temperature. The functional aerogel fiber fabric achieves high thermal insulation and photothermal modulation simultaneously at temperatures below 18 °C. The temperature of the thermochromic fabric was higher by 6 °C than that of the sample without the microcapsules at a light intensity of 0.2 W/cm2. In addition, the aerogel fibers mixed with two types of thermochromic microcapsules exhibit three color switches with fast response, a color-control precision of 0.2 °C, and good cycling performance. This smart aerogel fibers hold great promise for self-adaptive thermal management, temperature indication, information transfer, and anticounterfeiting in textiles

    Bioinspired Thermochromic Textile Based on Robust Cellulose Aerogel Fiber for Self-Adaptive Thermal Management and Dynamic Labels

    No full text
    Aerogel fiber has emerged recently for incorporation in personal thermal management textiles due to its flexibility, scalability, and ultrahigh porosity, which allows the body to keep warm via thermal isolation without energy consumption. However, the functionalization and intellectualization of cellulose-based aerogel fibers have not yet been fully developed. Herein, we propose a biomimicking design inspired by polar bear and Siamese cat hair that combines porous cellulose aerogel fiber (CAF) with reversible thermochromic microcapsules to mimic biological sensory and adaptive thermoregulation functions. The produced CAF has a controllable pore structure, a large specific surface area (230 m2/g), and excellent mechanical strength (∼15 MPa). Low-temperature darkening microcapsules have been incorporated into the robust CAF to spontaneously adjust color by perceiving the ambient temperature. The functional aerogel fiber fabric achieves high thermal insulation and photothermal modulation simultaneously at temperatures below 18 °C. The temperature of the thermochromic fabric was higher by 6 °C than that of the sample without the microcapsules at a light intensity of 0.2 W/cm2. In addition, the aerogel fibers mixed with two types of thermochromic microcapsules exhibit three color switches with fast response, a color-control precision of 0.2 °C, and good cycling performance. This smart aerogel fibers hold great promise for self-adaptive thermal management, temperature indication, information transfer, and anticounterfeiting in textiles

    Immunohistochemical staining of MMP-2 protein expression in tumors of tumor bearing mice.

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    <p>Minimum MMP-2 staining was seen in tumors resected at 16 HALO, while tumors resected at 10 HALO showed the highest MMP-2 staining (magnification, ×400).</p

    Western blot analysis of PER1 protein expression in tissues of patients with BSCC.

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    <p>The level of Tubulin in each sample is detected as an internal control. One representative of three independent experiments with similar results is shown. Lane 1: PER1 protein expression in cancerous tissues. Lane 2: PER1 protein expression in adjacent noncancerous tissues.</p
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