Street Art as Public Pedagogy & Community Literacy: What Walls Can Teach Us

This essay analyzes the street art project Stop Telling Women to Smile (STWTS) to argue that public art plays an essential, pedagogical role in enhancing literacy education and intercultural communication within our communities. Functioning as both a public pedagogy and community literacy, STWTS demonstrates the power of public art to address injustice and provoke community conversation. To conclude, the essay calls literacy educators to expand the sites of pedagogy to include the everyday literacies students encounter within local public spaces

Transformative Learning, Affect, and Reciprocal Care in Community Engagement

Drawing on interviews with writing teachers, this article highlights some of the affective responses that may arise for students, community partners, and teachers when we situate our pedagogies in public sites beyond the classroom. I analyze a teacher-narrated moment of student distress to demonstrate how theories of transformative learning might help us productively theorize affect in service-learning and community-based education. To conclude, I offer a reciprocal model of care that employs tenets of feminist pedagogy, such as transparency and decentering of authority, and that acknowledges the valid emotions students, teachers, and community members may experience. I call for community literacy practitioners to see the power of all participants to both give and receive care in transformative education

Advancing Campus-Community Partnerships: Standpoint Theory and Course Re- Design

Service-learning pedagogies attempt to bridge the often-distant realms of work in the academy with that of the surrounding community. However, in practice, a true partnership among stakeholders can be challenging to achieve. For this project, I invited three former students and the director of a local non-profit to partner with me in an important aspect of academic work: course redesign. Through the lens of standpoint theory, we see that students and community partners hold unique standpoints, yet all too often their voices are marginalized. I assert that their standpoints offer l essential contributions to the course re-design process

The Risks of Engagement: Infrastructures of Place-Based Pedagogy in Urban Midwestern Contexts

I was drawn to panel A.04 because of my interests in place-based pedagogy. In fact, later that day I gave a presentation on a place-based approach to mobile composition, drawing examples from my teaching (C.05). One of the aspects of this panel that I found particularly engaging was the way that each presenter took a different approach to his or her attention to issues of place. The projects were quite diverse, but there were clearly overlapping connections in terms of how our local geographies, urban spaces, and communities have important implications for the teaching of writing and rhetoric. I walked away from the panel energized with a swirl of ideas for teaching and research

Androgen receptor phosphorylation at serine 81 and serine 213 in castrate-resistant prostate cancer

Background: Despite increases in diagnostics and effective treatments, over 300,000 men die from prostate cancer highlighting the need for specific and differentiating biomarkers. AR phosphorylation associates with castrate-resistance, with pARser213 promoting transcriptional activity. We hypothesise that combined pARser81 and pARser213 reduces survival and would benefit from dual-targeting androgen-dependent and Akt-driven disease. Methods: Immunohistochemistry and immunofluorescence were performed on matched hormone-naive and castrate-resistant prostate cancer samples. TempO-Seq gene profiling was analysed using DESeq2 package. LNCaP-AI cells were stimulated with DHT or EGF. WST-1 assays were performed to determine effects of Enzalutamide and BKM120 on cell viability. Results: Following the development of castrate-resistance, pARser81 expression reduced and pARser213 expression increased. Castrate-resistance pARser81 expression was not associated with survival but high pARser213 expression was associated with reduced survival from relapse. Combined high pARser81 and pARser213 was associated with reduced survival from relapse. pARser81 expression was induced by 10 nM DHT or 10 nM EGF and pARser213 expression was induced by treatment with 10 nM EGF in LNCaP-AI cells. Cell viability was reduced following treatment with 10 nM Enzalutamide and 10 nM BKM120. Eight genes were differentially expressed between hormone-naive and castrate-resistant tumours and twenty-five genes were differentially expressed between castrate-resistant tumours with high and low pARser213 expression. Conclusion: Combined pARser81 and pARser213 provides a novel prognostic biomarker for castrate-resistant disease and a potential predictive and therapeutic target for prostate cancer. Further studies will be required to investigate the combined effects of targeting AR and PI3K/AKT signalling

Leadership As We Know It

Leadership as We Know it is a collection of insights into modern leadership compiled by graduate students in Winona State University’s Leadership Education program during the Spring 2019 semester in a course aptly titled, Change Leadership. Each chapter was penned by one of 20 unique class members who offer their vision of leadership based upon their eclectic personal backgrounds and professional experiences, whose fields include athletics, business, education, and more. These diverse narratives offer something for everyone; whether it be a veteran or blossoming leader eager to continue their growth and evolution. Leadership as We Know it provides accounts from seasoned professionals who oversee their own organizational departments as well as emerging leaders just beginning their careers. Throughout these unique stories, clear patterns will emerge for the reader in what it takes to inspire change and provide authentic leadership for followers.https://openriver.winona.edu/leadershipeducationbooks/1003/thumbnail.jp

Mobilization of genomic islands of Staphylococcus aureus by temperate bacteriophage

The virulence of Staphylococcus aureus, in both human and animal hosts, is largely influenced by the acquisition of mobile genetic elements (MGEs). Most S. aureus strains carry a variety of MGEs, including three genomic islands (νSaα, νSaβ, νSaγ) that are diverse in virulence gene content but conserved within strain lineages. Although the mobilization of pathogenicity islands, phages and plasmids has been well studied, the mobilization of genomic islands is poorly understood. We previously demonstrated the mobilization of νSaβ by the adjacent temperate bacteriophage ϕSaBov from strain RF122. In this study, we demonstrate that ϕSaBov mediates the mobilization of νSaα and νSaγ, which are located remotely from ϕSaBov, mostly to recipient strains belonging to ST151. Phage DNA sequence analysis revealed that chromosomal DNA excision events from RF122 were highly specific to MGEs, suggesting sequence-specific DNA excision and packaging events rather than generalized transduction by a temperate phage. Disruption of the int gene in ϕSaBov did not affect phage DNA excision, packaging, and integration events. However, disruption of the terL gene completely abolished phage DNA packing events, suggesting that the primary function of temperate phage in the transfer of genomic islands is to allow for phage DNA packaging by TerL and that transducing phage particles are the actual vehicle for transfer. These results extend our understanding of the important role of bacteriophage in the horizontal transfer and evolution of genomic islands in S. aureus

A Case Study of Highly Pathogenic Avian Influenza H5N1 At Bird Island, South Georgia: The First Documented Outbreak in the Subantarctic region

Capsule: HPAI H5N1 was documented for the first time in the subantarctic region on Bird Island, South Georgia, resulting in the mortality of Brown Skuas Stercorarius antarcticus, Gentoo Penguins Pygoscelis papua, Snowy Albatrosses Diomedea exulans, and Antarctic Fur Seals Arctocephalus gazella. Aims: The spread of the HPAI H5N1 subtype has had dramatic impacts on numerous populations of wild birds and mammals. We describe a case study that can inform the management of HPAI for conservation practitioners and researchers globally. Methods: We documented the detection, monitoring, and impact of the first known outbreak ofH5N1 HPAI in the subantarctic region, at Bird Island in South Georgia (−54.3582, −36.5112) during2023–2024. Deaths from HPAI were first suspected in September 2023 and later confirmed by genetic analysis. Results: In total, 77 Brown Skuas, 38 Gentoo penguins, and 58 Snowy Albatrosses were suspected to have died from HPAI infection, and HPAI was confirmed in 5 dead Antarctic Fur Seals. Total mortality was unknown for all species, as other individuals will have been scavenged before discovery, or died at sea. Conclusion: This case study provides lessons for the management, risk, safety considerations, and ethical decisions regarding animal welfare that may help guide research and management responses to HPAI outbreaks elsewhere, particularly in remote areas or in species of conservation concern