Treating Homeless Opioid Dependent Patients with Buprenorphine in an Office-Based Setting

CONTEXT Although office-based opioid treatment with buprenorphine (OBOT-B) has been successfully implemented in primary care settings in the US, its use has not been reported in homeless patients. OBJECTIVE To characterize the feasibility of OBOT-B in homeless relative to housed patients. DESIGN A retrospective record review examining treatment failure, drug use, utilization of substance abuse treatment services, and intensity of clinical support by a nurse care manager (NCM) among homeless and housed patients in an OBOT-B program between August 2003 and October 2004. Treatment failure was defined as elopement before completing medication induction, discharge after medication induction due to ongoing drug use with concurrent nonadherence with intensified treatment, or discharge due to disruptive behavior. RESULTS Of 44 homeless and 41 housed patients enrolled over 12 months, homeless patients were more likely to be older, nonwhite, unemployed, infected with HIV and hepatitis C, and report a psychiatric illness. Homeless patients had fewer social supports and more chronic substance abuse histories with a 3- to 6-fold greater number of years of drug use, number of detoxification attempts and percentage with a history of methadone maintenance treatment. The proportion of subjects with treatment failure for the homeless (21%) and housed (22%) did not differ (P=.94). At 12 months, both groups had similar proportions with illicit opioid use [Odds ratio (OR), 0.9 (95% CI, 0.5–1.7) P=.8], utilization of counseling (homeless, 46%; housed, 49%; P=.95), and participation in mutual-help groups (homeless, 25%; housed, 29%; P=.96). At 12 months, 36% of the homeless group was no longer homeless. During the first month of treatment, homeless patients required more clinical support from the NCM than housed patients. CONCLUSIONS Despite homeless opioid dependent patients' social instability, greater comorbidities, and more chronic drug use, office-based opioid treatment with buprenorphine was effectively implemented in this population comparable to outcomes in housed patients with respect to treatment failure, illicit opioid use, and utilization of substance abuse treatment

Polysomes of bovine anterior pituitary gland and their role in hormone and protein biosynthesis

This article does not have an abstract

Chaotic hysteresis in an adiabatically oscillating double well

We consider the motion of a damped particle in a potential oscillating slowly between a simple and a double well. The system displays hysteresis effects which can be of periodic or chaotic type. We explain this behaviour by computing an analytic expression of a Poincar'e map.Comment: 4 pages RevTeX, 3 PS figs, uses psfig.sty. Submitted to Phys. Rev. Letters. PS file also available at http://dpwww.epfl.ch/instituts/ipt/berglund.htm

Strontium-90 Liquid Concentration Solubility Correlation in the Hanford Tank Waste Operations Simulator

A new correlation was developed to estimate the concentration of strontium-90 in a waste solution based on total organic carbon. This correlation replaces the strontium-90 wash factors, and when applied in the Hanford Tank Waste Operations Simulator, significantly reduced the estimated quantity of strontium-90 in the delivered low-activity waste feed. This is thought to be a more realistic estimate of strontium-90 than using the wash-factor method

Quasi-equilibria in one-dimensional self-gravitating many body systems

The microscopic dynamics of one-dimensional self-gravitating many-body systems is studied. We examine two courses of the evolution which has the isothermal and stationary water-bag distribution as initial conditions. We investigate the evolution of the systems toward thermal equilibrium. It is found that when the number of degrees of freedom of the system is increased, the water-bag distribution becomes a quasi-equilibrium, and also the stochasticity of the system reduces. This results suggest that the phase space of the system is effectively not ergodic and the system with large degreees of freedom approaches to the near-integrable one.Comment: 21pages + 7 figures (available upon request), revtex, submitted to Physical Review

Solid molecular hydrogen: The Broken Symmetry Phase

By performing constant-pressure variable-cell ab initio molecular dynamics simulations we find a quadrupolar orthorhombic structure, of $Pca2_1$ symmetry, for the broken symmetry phase (phase II) of solid H2 at T=0 and P =110 - 150 GPa. We present results for the equation of state, lattice parameters and vibronic frequencies, in very good agreement with experimental observations. Anharmonic quantum corrections to the vibrational frequencies are estimated using available data on H2 and D2. We assign the observed modes to specific symmetry representations.Comment: 5 pages (twocolumn), 4 Postscript figures. To appear in Phys. Rev. Let

Relaxation processes in one-dimensional self-gravitating many-body systems

Though one dimensional self-gravitating $N$-body systems have been studied for three decade, the nature of relaxation was still unclear. There were inconsistent results about relaxation time; some initial state relaxed in the time scale $T\sim N\,t_c$, but another state did not relax even after $T\sim N^2\,t_c$, where $t_c$ is the crossing time. The water-bag distribution was believed not to relax after $T\sim N^2\,t_c$. In our previous paper, however, we found there are two different relaxation times in the water-bag distribution;in the faster relaxation ( microscopic relaxation ) the equipartition of energy distribution is attains but the macroscopic distribution turns into the isothermal distribution in the later relaxation (macroscopic relaxation). In this paper, we investigated the properties of the two relaxation. We found that the microscopic relaxation time is $T\sim N\,t_c$, and the macroscopic relaxation time is proportional to $N\,t_c$, thus the water-bag does relax. We can see the inconsistency about the relaxation times is resolved as that we see the two different aspect of relaxations. Further, the physical mechanisms of the relaxations are presented.Comment: 11 pages, uuencoded, compressed Postscript, no figure, figures available at ftp://ferio.mtk.nao.ac.jp/pub/tsuchiya/Tsuchiya95.tar.g

Влияние термомеханической обработки на структуру, механические и трибологические свойства композитов Al-Si-Sn

Исследование влияния режима спекания порошковых прессовок, а также последующей их деформационной обработки методом горячего доуплотнения и равноканального углового прессования (РКУП) на результирующую структуру, механические и трибологические свойства композитов (Al-Si)-40Sn.Investigation of the effect of sintering regimes of powder compacts, as well as their deformation treatment by hot doping and equal-channel angular pressing (ECAP) on the resulting structure, mechanical and tribological properties of composites (Al-Si)-40Sn

Obeying the rules of the road: Procedural justice, social identity and normative compliance

Why do people comply with traffic laws and regulations? Road traffic policing tends to be premised on the idea that people comply when they are presented with a credible risk of sanction in the event of non-compliance. Such an instrumental model of compliance contrasts with the normative account offered by procedural justice theory, in which compliance is encouraged by legitimate legal authorities. Comparing these two accounts, we find evidence that both instrumental and normative factors explain variance in motorists’ self-reported propensity to offend. Extending the standard procedural justice account, we also find that it is social identity – not legitimacy – that forms the ‘bridge’ linking procedural fairness and compliance, at least according to a definition of legitimacy that combines felt obligation and moral endorsement. Fair treatment at the hands of police officers seems to enhance identification with the social group the police represent, and in turn, identification seems to motivate adherence to rules (laws) governing social behavior. These findings have implications not only for understandings of legal compliance, but also our understanding of why procedural justice motivates compliance, and the role of procedural justice in promoting social cohesion