Mejoras en el sistema MOIRA para su aplicación a los emplazamientos nucleares fluviales españoles

Entre las posibles secuelas de un accidente nuclear hay que contar con la contaminación radiactiva a medio y largo plazo de los sistemas acuáticos de agua dulce. Frente a ese problema, es fundamental disponer de una evaluación realista del impacto radiológico, ecológico, social y económico de las posibles estrategias de gestión, para poder adoptar las decisiones más convenientes de forma racional. MOIRA es un sistema de ayuda a la decisión desarrollado en el curso de los Programas Marco Europeos con participación de la UPM, que ha sido mejorado y adaptado a los emplazamientos nucleares españoles en los últimos años en el contexto del Proyecto ISIDRO, patrocinado por el Consejo de Seguridad Nuclear, con la participación del CIEMAT y la UPM. El trabajo se centra en esos avances, principalmente relacionados con los sistemas hidráulicos complejos como los de los ríos Tajo, Ebro y Júcar, en los que se ubican varias centrales nucleares españolas

AKSZ-BV Formalism and Courant Algebroid-induced Topological Field Theories

We give a detailed exposition of the Alexandrov-Kontsevich-Schwarz- Zaboronsky superfield formalism using the language of graded manifolds. As a main illustarting example, to every Courant algebroid structure we associate canonically a three-dimensional topological sigma-model. Using the AKSZ formalism, we construct the Batalin-Vilkovisky master action for the model.Comment: 13 pages, based on lectures at Rencontres mathematiques de Glanon 200

Preparedness for the Long-Term Management of Contaminated Freshwater Bodies and Catchments. A Decision making exercise with the MOIRA system

In the mid-long-term after a nuclear accident, the contamination of drinking water sources, fish and other aquatic foodstuffs, irrigation supplies and people’s exposure during recreational activities may create considerable public concern, even though dose assessment may in certain situations indicate lesser importance than for other sources, as clearly experienced in the aftermath of accidents like Chernobyl. The MOIRA system is designed to allow for a reliable assessment of the long-term evolution of the radiological situation and of possible alternative rehabilitation strategies, including an objective evaluation of their social, economic and ecological impacts in a rational and comprehensive manner. MOIRA also features a decision analysis methodology, making use of multi-attribute analysis, which can take into account the preferences and needs of different types of stakeholders. A decision-making exercise regarding such problems, in which MOIRA has been be used as a decision support tool, was organised in Spain involving the organizations responsible for emergency management and the affected services, as well as local and regional stakeholders and several international observers. The system resulted very helpful in assessing the overall situation and the alternative management strategies and also facilitated the interaction between agencies which reached a better common understanding of all related issues

Long-term management of contaminated freshwater bodies and catchments. Decision making exercise with the MOIRA system

In the mid-long-term after a nuclear accident, the contamination oi" drinking water sources, fish and other aquatic foodstuffs, irrigation supplies and people's exposure during recreational activities may create considerable public concern, even though dose assessment may in certain situations indicate lesser importance than for other sources, as clearly experienced in the aftermath of major accidents, like Chernobyl. For such a problem, definition of appropriate remediation strategies and wide stakeholder involvement are crucial to guarantee the acceptability of the implemented management solutions. The MOIRA system was developed during the IV Euratom Framework Research Program me (EFRP) and tested and compared with other models inside the EVANET-IIYDRA network of the V EFRJP. It was designed to allow for a reliable assessment of possible alternative management strategies, including an objective evaluation of their economic, social and ecological impacts in a rational and comprehensive manner. MOIRA considers countermeasures effectiveness and a full scope decision analysis methodology, making use of multi-attribute analysis (MAA).which can take into account the preferences and the needs of different l\ pes of stakeholders in cases of higher complexity. This work presents and discusses the main conclusions derived from a decision-making exercise regarding such problems in which MOIRA has been be used as a decision support tool. The exercise was organised in the frame of the Nuclear Safety Council (CSN) Annual Exercises and Simulations Program 2007 and within the El'RANOS Project of the 6th F.FRP.It has featured the participation of the organizations responsible for emergency management and the affected services, as well as local and regional stakeholders and several international observers

MOIRA-PLUS use in decision making on the long-term management of contaminated freshwater bodies and catchments

In the mid-long-term after a nuclear accident, the contamination of drinking water sources, fish and other aquatic foodstuffs, irrigation supplies and people?s exposure during recreational activities may create considerable public concern, even though dose assessment may in certain situations indicate lesser importance than for other sources, as clearly experienced in the aftermath of past accidents. In such circumstances there are a number of available countermeasure options, ranging from specific chemical treatment of lakes to bans on fish ingestion or on the use of water for crop irrigation. The potential actions can be broadly grouped into four main categories, chemical, biological, physical and social. In some cases a combination of actions may be the optimal strategy and a decision support system (DSS) like MOIRA-PLUS can be of great help to optimise a decision. A further option is of course not to take any remedial actions, although this may also have significant socio-economic repercussions which should be adequately evaluated. MOIRA-PLUS is designed to allow for a reliable assessment of the long-term evolution of the radiological situation and of feasible alternative rehabilitation strategies, including an objective evaluation of their social, economic and ecological impacts in a rational and comprehensive manner. MOIRA-PLUS also features a decision analysis methodology, making use of multi-attribute analysis, which can take into account the preferences and needs of different types of stakeholders. The main functions and elements of the system are described summarily. Also the conclusions from end-user?s experiences with the system are discussed, including exercises involving the organizations responsible for emergency management and the affected services, as well as different local and regional stakeholders. MOIRAPLUS has proven to be a mature system, user friendly and relatively easy to set up. It can help to better decisionmaking by enabling a realistic evaluation of the complete impacts of possible recovery strategies. Also, the interaction with stakeholders has allowed identifying improvements of the system that have been recently implemented

Acyclic Petri and workflow nets with resets

In this paper we propose two new subclasses of Petri nets with resets, for which the reachability and coverability problems become tractable. Namely, we add an acyclicity condition that only applies to the consumptions and productions, not the resets. The first class is acyclic Petri nets with resets, and we show that coverability is PSPACE-complete for them. This contrasts the known Ackermann-hardness for coverability in (not necessarily acyclic) Petri nets with resets. We prove that the reachability problem remains undecidable for acyclic Petri nets with resets. The second class concerns workflow nets, a practically motivated and natural subclass of Petri nets. Here, we show that both coverability and reachability in acyclic workflow nets with resets are PSPACE-complete. Without the acyclicity condition, reachability and coverability in workflow nets with resets are known to be equally hard as for Petri nets with resets, that being Ackermann-hard and undecidable, respectively

Total Zinc Intake May Modify the Glucose-Raising Effect of a Zinc Transporter (SLC30A8) Variant

Objective: Many genetic variants have been associated with glucose homeostasis and type 2 diabetes in genome-wide association studies. Zinc is an essential micronutrient that is important for β-cell function and glucose homeostasis. We tested the hypothesis that zinc intake could influence the glucose-raising effect of specific variants. Research Design and Methods: We conducted a 14-cohort meta-analysis to assess the interaction of 20 genetic variants known to be related to glycemic traits and zinc metabolism with dietary zinc intake (food sources) and a 5-cohort meta-analysis to assess the interaction with total zinc intake (food sources and supplements) on fasting glucose levels among individuals of European ancestry without diabetes. Results: We observed a significant association of total zinc intake with lower fasting glucose levels (β-coefficient ± SE per 1 mg/day of zinc intake: −0.0012 ± 0.0003 mmol/L, summary P value = 0.0003), while the association of dietary zinc intake was not significant. We identified a nominally significant interaction between total zinc intake and the SLC30A8 rs11558471 variant on fasting glucose levels (β-coefficient ± SE per A allele for 1 mg/day of greater total zinc intake: −0.0017 ± 0.0006 mmol/L, summary interaction P value = 0.005); this result suggests a stronger inverse association between total zinc intake and fasting glucose in individuals carrying the glucose-raising A allele compared with individuals who do not carry it. None of the other interaction tests were statistically significant. Conclusions: Our results suggest that higher total zinc intake may attenuate the glucose-raising effect of the rs11558471 SLC30A8 (zinc transporter) variant. Our findings also support evidence for the association of higher total zinc intake with lower fasting glucose levels

Total zinc intake may modify the glucose-raising effect of a zinc transporter (SLC30A8) variant: a 14-cohort meta-analysis.

OBJECTIVE: Many genetic variants have been associated with glucose homeostasis and type 2 diabetes in genome-wide association studies. Zinc is an essential micronutrient that is important for β-cell function and glucose homeostasis. We tested the hypothesis that zinc intake could influence the glucose-raising effect of specific variants. RESEARCH DESIGN AND METHODS: We conducted a 14-cohort meta-analysis to assess the interaction of 20 genetic variants known to be related to glycemic traits and zinc metabolism with dietary zinc intake (food sources) and a 5-cohort meta-analysis to assess the interaction with total zinc intake (food sources and supplements) on fasting glucose levels among individuals of European ancestry without diabetes. RESULTS: We observed a significant association of total zinc intake with lower fasting glucose levels (β-coefficient ± SE per 1 mg/day of zinc intake: -0.0012 ± 0.0003 mmol/L, summary P value = 0.0003), while the association of dietary zinc intake was not significant. We identified a nominally significant interaction between total zinc intake and the SLC30A8 rs11558471 variant on fasting glucose levels (β-coefficient ± SE per A allele for 1 mg/day of greater total zinc intake: -0.0017 ± 0.0006 mmol/L, summary interaction P value = 0.005); this result suggests a stronger inverse association between total zinc intake and fasting glucose in individuals carrying the glucose-raising A allele compared with individuals who do not carry it. None of the other interaction tests were statistically significant. CONCLUSIONS: Our results suggest that higher total zinc intake may attenuate the glucose-raising effect of the rs11558471 SLC30A8 (zinc transporter) variant. Our findings also support evidence for the association of higher total zinc intake with lower fasting glucose levels