6 research outputs found
S铆ndrome de Realimentaci贸n: Revisi贸n de tema
The refeeding syndrome (SR) is constituted by a series of metabolic alterations, produced by the reintroduction of feeding after a prolonged period of fasting. During the fasting period the body enters in a state of catabolic metabolism; which later becomes an anabolic state with the reintroduction of food. This process explains the different hydroelectrolytic alterations.
Prevention is the mainstay of treatment in this condition, the NICE has developed a series of criteria to group people according to risk. Among the patients with the highest risk are those who present some oncological pathology, chronic disease, eating disorders, among others. SR requires early management based on an adequate diagnosis and the adequate caloric and electrolytic administration according to each case.El s铆ndrome de realimentaci贸n (SR) se encuentra constituido por una serie de alteraciones metab贸licas, producidas por el reinicio de la alimentaci贸n posterior a un periodo prolongado de ayuno. Durante el periodo de ayuno, el cuerpo entra en un estado de metabolismo catab贸lico; el cual posteriormente se convierte en un estado anab贸lico con la reintroducci贸n de la alimentaci贸n. Dicho proceso explica las distintas alteraciones hidroelectrol铆ticas.
La prevenci贸n constituye el pilar de tratamiento en este padecimiento, el NICE ha elaborado una serie de criterios para agrupar a las personas seg煤n el riesgo. Entre los pacientes con mayor riesgo se encuentran aquellos que presentan alguna patolog铆a oncol贸gica, enfermedad cr贸nica, trastornos alimenticios, entre otros. El SR requiere de un manejo precoz basado en un adecuado diagn贸stico y la correcta administraci贸n tanto cal贸rica como electrol铆tica seg煤n cada caso
REVISI脫N DE TEMA: PAPEL DE LA ACTIVIDAD F脥SICA EN EL MANEJO NO FARMACOL脫GICO DEL S脥NDROME DE INTESTINO IRRITABLE
Irritable bowel syndrome (IBS) is the most common gastroenterological diagnosis, with a high overall prevalence ranging from 5% to 21%. This chronic recurrent disease course is characterized by its overlap with other functional disorders and its impact on quality of life of the patients. Currently there are few treatments that offer satisfactory symptomatic relief, so in the effective management of IBS importance has been given to counseling on changes in lifestyle, physical activity, diet, among others. This approach to personal effort by the patient is based on the relationship of the chronic stress state with the exacerbation of IBS symptoms. Brain-gut interactions may play a role in the association between physical activity and symptoms in IBS. Most studies agree that interventions that promote increased physical activity improve IBS gastrointestinal symptoms; as well as different aspects of quality of life, fatigue, depression and long-term anxietyEl s铆ndrome de intestino irritable (SII) es el diagn贸stico gastroenterol贸gico m谩s com煤n, con una elevada prevalencia global que oscila entre el 5% al 21%. Esta enfermedad de curso recurrente cr贸nico se caracteriza por su traslape con otros trastornos funcionales y su afectaci贸n en la calidad de vida de los pacientes. Actualmente son pocos los tratamientos que ofrecen un alivio sintom谩tico satisfactorio, por lo que en el manejo efectivo del SII se ha dado importancia a la consejer铆a sobre cambios en el estilo de vida, actividad f铆sica, dieta, entre otros. Este enfoque de esfuerzo personal por parte del paciente se sustenta en la relaci贸n del estado de estr茅s cr贸nico con la exacerbaci贸n de los s铆ntomas de SII. Las interacciones cerebro-intestino pueden jugar un rol en la asociaci贸n entre la actividad f铆sica y los s铆ntomas en el SII. La mayor铆a de estudios concuerdan que las intervenciones que propician el aumento de la actividad f铆sica mejoran los s铆ntomas gastrointestinales del SII; as铆 como diferentes aspectos de la calidad de vida, fatiga, depresi贸n y ansiedad a largo plazo
Enfermedad celiaca e infertilidad no explicada: papel del tamizaje. Revisi贸n de literatura.
Celiac disease (CD) is a chronic inflammatory disorder caused by an abnormal immune response induced by a permanent intolerance to wheat, barley and rye in the diet. This diagnosis is performed by blood screening tests in conjunction with endoscopic confirmation and biopsy. CD has been associated with other
autoimmune diseases and systemic manifestations. In recent years, the relationship of CD with unexplained infertility has been studied with greater relevance. Among the pathophysiological mechanisms nutritional deficiency and specific autoimmune processes are highlighted either at the time of conception or that these mechanisms are priorly developed causing ovarian deficiency . CD screening in infertile patients has been proposed ;however, this has generated controversy due to its utility. Although the relationship between these pathologies is strong, it has been shown in different studies that the utility when performing such routine screening depends on the type of population and its prevalenceLa enfermedad cel铆aca (EC) es un trastorno inflamatorio cr贸nico causado por una respuesta inmune anormal inducida por una intolerancia permanente al trigo, la cebada y el centeno en la dieta. Dicho diagnostico se realiza por medio de pruebas sangu铆neas de tamizaje en conjunto con confirmaci贸n endosc贸pica y biopsia. La EC se ha asociado a otras enfermedades autoinmunes y manifestaciones sist茅micas. En los 煤ltimos a帽os se ha estudiado con mayor relevancia la relaci贸n de EC con la infertilidad no explicada, dentro de los mecanismos fisiopatol贸gicos se destaca la deficiencia nutricional y procesos autoinmunes especificos ya sea en el momento de la concepci贸n o que estos mecanismos se desarrollen previo provocando deficiencia ov谩rica. Se ha propuesto realizar el tamizaje de EC en pacientes infertiles, sin embargo ha generado controversia debido a su utilidad. Si bien es cierto la relaci贸n entre dichas patolog铆as es fuerte, se ha demostrado en los diferentes estudios que la utillidad en realizar dicho tamizaje de rutina depende del tipo de poblaci贸n y su prevalenci
Terrorists, their motives, and their victims as perceived by Israeli Jewish and Arab children and adolescents
Spike Ca2+ influx upmodulates the spike afterdepolarization and bursting via intracellular inhibition of KV7/M channels
In principal brain neurons, activation of Ca2+ channels during an action potential, or spike, causes Ca2+ entry into the cytosol within a millisecond. This in turn causes rapid activation of large conductance Ca2+-gated channels, which enhances repolarization and abbreviates the spike. Here we describe another remarkable consequence of spike Ca2+ entry: enhancement of the spike afterdepolarization. This action is also mediated by intracellular modulation of a particular class of K+ channels, namely by inhibition of KV7 (KCNQ) channels. These channels generate the subthreshold, non-inactivating M-type K+ current, whose activation curtails the spike afterdepolarization. Inhibition of KV7/M by spike Ca2+ entry allows the spike afterdepolarization to grow and can convert solitary spikes into high-frequency bursts of action potentials. Through this novel intracellular modulatory action, Ca2+ spike entry regulates the discharge mode and the signalling capacity of principal brain neurons