84 research outputs found
SS25 Participation in the Vascular Quality Initiative (VQI) Is Associated With Improved Perioperative Medication Use and Longer Patient Survival
The Keck Planet Search: Detectability and the Minimum Mass and Orbital Period Distribution of Extrasolar Planets
We analyze 8 years of precise radial velocity measurements from the Keck
Planet Search, characterizing the detection threshold, selection effects, and
completeness of the survey. We carry out a systematic search for planets by
assessing the false alarm probability associated with Keplerian orbit fits to
the data. This allows us to understand the detection threshold for each star in
terms of the number and time baseline of the observations, and size of
measurement errors and stellar jitter. We show that all planets with orbital
periods 20 m/s, and eccentricities <0.6 have
been announced, and summarize the candidates at lower amplitudes and longer
orbital periods. For the remaining stars, we calculate upper limits on the
velocity amplitude of a companion, typically 10 m/s, and use the non-detections
to derive completeness corrections at low amplitudes and long orbital periods.
We give the fraction of stars with a planet as a function of planet mass and
orbital period, and extrapolate to long period orbits and low planet masses. A
power law fit for planet masses >0.3 Jupiter masses and periods <2000 days
gives a mass-period distribution dN=C M^\alpha P^\beta dlnM dlnP with
\alpha=-0.31 \pm 0.2, \beta=0.26\pm 0.1, and the normalization constant C such
that 10.5% of solar type stars have a planet with mass in the range 0.3-10
Jupiter masses and orbital period 2-2000 days. The orbital period distribution
shows an increase in the planet fraction by a factor of 5 for orbital periods
beyond 300 days. Extrapolation gives 17-20% of stars having gas giant planets
within 20 AU. Finally, taking into account differences in detectability, we
find that M dwarfs are 3 to 10 times less likely to harbor a Jupiter mass
planet than solar type stars.Comment: 20 pages, 17 figures, accepted for publication in PAS
Mitochondrial physiology
As the knowledge base and importance of mitochondrial physiology to evolution, health and disease expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory establishes the mechanism of energy transformation and coupling in oxidative phosphorylation. The unifying concept of the protonmotive force provides the framework for developing a consistent theoretical foundation of mitochondrial physiology and bioenergetics. We follow the latest SI guidelines and those of the International Union of Pure and Applied Chemistry (IUPAC) on terminology in physical chemistry, extended by considerations of open systems and thermodynamics of irreversible processes. The concept-driven constructive terminology incorporates the meaning of each quantity and aligns concepts and symbols with the nomenclature of classical bioenergetics. We endeavour to provide a balanced view of mitochondrial respiratory control and a critical discussion on reporting data of mitochondrial respiration in terms of metabolic flows and fluxes. Uniform standards for evaluation of respiratory states and rates will ultimately contribute to reproducibility between laboratories and thus support the development of data repositories of mitochondrial respiratory function in species, tissues, and cells. Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ultimately further discovery
Mitochondrial physiology
As the knowledge base and importance of mitochondrial physiology to evolution, health and disease expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory establishes the mechanism of energy transformation and coupling in oxidative phosphorylation. The unifying concept of the protonmotive force provides the framework for developing a consistent theoretical foundation of mitochondrial physiology and bioenergetics. We follow the latest SI guidelines and those of the International Union of Pure and Applied Chemistry (IUPAC) on terminology in physical chemistry, extended by considerations of open systems and thermodynamics of irreversible processes. The concept-driven constructive terminology incorporates the meaning of each quantity and aligns concepts and symbols with the nomenclature of classical bioenergetics. We endeavour to provide a balanced view of mitochondrial respiratory control and a critical discussion on reporting data of mitochondrial respiration in terms of metabolic flows and fluxes. Uniform standards for evaluation of respiratory states and rates will ultimately contribute to reproducibility between laboratories and thus support the development of data repositories of mitochondrial respiratory function in species, tissues, and cells. Clarity of concept and consistency of nomenclature facilitate effective transdisciplinary communication, education, and ultimately further discovery
Mitochondrial heat shock protein-90 modulates vascular smooth muscle cell survival and the vascular injury response in vivo.
Follow-up Surveillance After Endovascular Aneurysm Repair: Less Is More
Comment on: Postoperative Surveillance and Long-term Outcomes After Endovascular Aneurysm Repair Among Medicare Beneficiaries. [JAMA Surg. 2015
- …