Optimal functional outcome measures for assessing treatment for Dupuytren's disease: A systematic review and recommendations for future practice

This article is available through the Brunel Open Access Publishing Fund. Copyright © 2013 Ball et al.; licensee BioMed Central Ltd.Background: Dupuytren's disease of the hand is a common condition affecting the palmar fascia, resulting in progressive flexion deformities of the digits and hence limitation of hand function. The optimal treatment remains unclear as outcomes studies have used a variety of measures for assessment. Methods: A literature search was performed for all publications describing surgical treatment, percutaneous needle aponeurotomy or collagenase injection for primary or recurrent Dupuytren’s disease where outcomes had been monitored using functional measures. Results: Ninety-one studies met the inclusion criteria. Twenty-two studies reported outcomes using patient reported outcome measures (PROMs) ranging from validated questionnaires to self-reported measures for return to work and self-rated disability. The Disability of Arm, Shoulder and Hand (DASH) score was the most utilised patient-reported function measure (n=11). Patient satisfaction was reported by eighteen studies but no single method was used consistently. Range of movement was the most frequent physical measure and was reported in all 91 studies. However, the methods of measurement and reporting varied, with seventeen different techniques being used. Other physical measures included grip and pinch strength and sensibility, again with variations in measurement protocols. The mean follow-up time ranged from 2 weeks to 17 years. Conclusions: There is little consistency in the reporting of outcomes for interventions in patients with Dupuytren’s disease, making it impossible to compare the efficacy of different treatment modalities. Although there are limitations to the existing generic patient reported outcomes measures, a combination of these together with a disease-specific questionnaire, and physical measures of active and passive individual joint Range of movement (ROM), grip and sensibility using standardised protocols should be used for future outcomes studies. As Dupuytren’s disease tends to recur following treatment as well as extend to involve other areas of the hand, follow-up times should be standardised and designed to capture both short and long term outcomes

MEMS-integrated load cell for measuring pressure, erosion, and deposition in dynamic environmental flows

A microelectromechanical system-based load cell is integrated with signal conditioning circuitry, temperature, and tilt sensors for measurement of sediment-fluid interaction and flow under turbulent conditions. Such an instrument has potential value for quantifying geophysical flows and sediment dynamics within a range of environments. Sensor sensitivity is tested to a mass of 0.5 g but can be shown theoretically to extend to 50 mg. The sensor is found to have no attenuation of frequencies up to 2.5 Hz and would therefore be suitable for monitoring turbulent flow. Laboratory flume experiments, simulating a dam burst, demonstrate the applicability of the sensor for measuring highly dynamic and transient flow phenomena in unprecedented detail

Does a Finer Level of Detail of a 3D City Model Bring an Improvement for Estimating Shadows?

3D city models are characterised by the level of detail (LOD), which indicates their spatio-semantic complexity. Modelling data in finer LODs results in visually appealing models and opens the door for more applications, but that is at the expense of increased costs of acquisition, and larger storage footprint. In this paper we investigate whether the improvement in the LOD of a 3D building model brings more accurate shadow predictions. The result is that in most cases the improvement is negligible. Hence, the higher cost of acquiring 3D models in finer LODs is not always justified. However, the exact performance is influenced by the architecture of a building. The paper also describes challenges in experiments such as this one. For instance, defining error metrics may not always be simple, and the big picture of errors should be considered, as the impact of errors ultimately depends on the intended use case. For example, an error of a certain magnitude in estimating the shadow may not significantly affect visualisation purposes, but the same error may considerably influence the estimation of the photovoltaic potential.Urban Data Scienc