Holographic Nuclear Matter in AdS/QCD

We study the physics with finite nuclear density in the framework of AdS/QCD with holographic baryon field included. Based on a mean field type approach, we introduce the nucleon density as a bi-fermion condensate of the lowest mode of the baryon field and calculate the density dependence of the chiral condensate and the nucleon mass. We observe that the chiral condensate as well as the mass of nucleon decrease with increasing nuclear density. We also consider the mass splitting of charged vector mesons in iso-spin asymmetric nuclear matter.Comment: 16 pages, 3 figures, two references are added, typo corrected, section 3.3 remove

A New SX Phe Star in the Globular Cluster M15

A new SX Phe star (labelled SXP1) found from $BV$ CCD photometry is the first to be discovered in the globular cluster M15. It is a blue straggler and is located 102\arcsec.8 north and 285\arcsec.6 west of the center of M15 \citep{har96}. Mean magnitudes of SXP1 are = 18$\fm$671 and = 18\fm445. The amplitude of variability of SXP1 is measured to be $\Delta V \approx 0.15$. From multiple-frequency analysis based on the Fourier decomposition method, we detect two very closely separated pulsating frequencies: the primary frequency at $f_1=24.630$ c/d for both $B$- and $V$-bands, and the secondary frequency at $f_2=24.338$ c/d for the $B$-band and 24.343 c/d for the $V$-band. This star is the second among known SX Phe stars found to pulsate with very closely separated frequencies ($f_2/f_1\ge0.95$). These frequencies may be explained by excitation of nonradial modes; however, we have an incomplete understanding of this phenomenon in the case of SX Phe stars with relatively high amplitudes. The metallicity-period and the variability amplitude-period relations for SXP1 in M15 are found to be consistent with those for SX Phe stars in other globular clusters.Comment: 15 pages with 6 figures, accepted by the Astronomical Journal (scheduled May 2001

The role of atrial natriuretic peptide to attenuate inflammation in a mouse skin wound and individually perfused rat mesenteric microvessels.

We tested the hypothesis that the anti-inflammatory actions of atrial natriuretic peptide (ANP) result from the modulation of leukocyte adhesion to inflamed endothelium and not solely ANP ligation of endothelial receptors to stabilize endothelial barrier function. We measured vascular permeability to albumin and accumulation of fluorescent neutrophils in a full-thickness skin wound on the flank of LysM-EGFP mice 24 h after formation. Vascular permeability in individually perfused rat mesenteric microvessels was also measured after leukocytes were washed out of the vessel lumen. Thrombin increased albumin permeability and increased the accumulation of neutrophils. The thrombin-induced inflammatory responses were attenuated by pretreating the wound with ANP (30 min). During pretreatment ANP did not lower permeability, but transiently increased baseline albumin permeability concomitant with the reduction in neutrophil accumulation. ANP did not attenuate acute increases in permeability to histamine and bradykinin in individually perfused rat microvessels. The hypothesis that anti-inflammatory actions of ANP depend solely on endothelial responses that stabilize the endothelial barrier is not supported by our results in either individually perfused microvessels in the absence of circulating leukocytes or the more chronic skin wound model. Our results conform to the alternate hypothesis that ANP modulates the interaction of leukocytes with the inflamed microvascular wall of the 24 h wound. Taken together with our previous observations that ANP reduces deformability of neutrophils and their strength of attachment, rolling, and transvascular migration, these observations provide the basis for additional investigations of ANP as an anti-inflammatory agent to modulate leukocyte-endothelial cell interactions

Identifying entanglement using quantum "ghost" interference and imaging

We report a quantum interference and imaging experiment which quantitatively demonstrates that Einstein-Podolsky-Rosen (EPR) type entangled two-photon states exhibit both momentum-momentum and position-position correlations, stronger than any classical correlation. The measurements show indeed that the uncertainties in the sum of momenta and in the difference of positions of the entangled two-photon satisfy both EPR inequalities D(k1+k2)<min(D(k1),D(k2)) and D(x1-x2)<min(D(x1),D(x2)). These two inequalities, together, represent a non-classicality condition. Our measurements provide a direct way to distinguish between quantum entanglement and classical correlation in continuous variables for two-photons/two photons systems.Comment: We have changed Eq.(2) from one inequality to two inequalities. The two expressions are actually consistent with each other, but the new one represents a more stringent condition for entanglement and, in our opinion, better explains the original idea of EPR. We have clarified this point in the paper. 4 pages; submitted to PR

Klotho controls the brain-immune system interface in the choroid plexus.

Located within the brain's ventricles, the choroid plexus produces cerebrospinal fluid and forms an important barrier between the central nervous system and the blood. For unknown reasons, the choroid plexus produces high levels of the protein klotho. Here, we show that these levels naturally decline with aging. Depleting klotho selectively from the choroid plexus via targeted viral vector-induced knockout in Klotho flox/flox mice increased the expression of multiple proinflammatory factors and triggered macrophage infiltration of this structure in young mice, simulating changes in unmanipulated old mice. Wild-type mice infected with the same Cre recombinase-expressing virus did not show such alterations. Experimental depletion of klotho from the choroid plexus enhanced microglial activation in the hippocampus after peripheral injection of mice with lipopolysaccharide. In primary cultures, klotho suppressed thioredoxin-interacting protein-dependent activation of the NLRP3 inflammasome in macrophages by enhancing fibroblast growth factor 23 signaling. We conclude that klotho functions as a gatekeeper at the interface between the brain and immune system in the choroid plexus. Klotho depletion in aging or disease may weaken this barrier and promote immune-mediated neuropathogenesis

A 10 GHz Quasi-Optical Grid Amplifier Using Integrated HBT Differential Pairs

We report the fabrication and testing of a 10 GHz grid amplifier utilizing sixteen GaAs chips each containing an HBT differential pair plus integral bias/feedback resistors. The overall amplifier consists of a 4x4 array of unit cells on an RT Duroid™ board having a relative permittivity of 2.2. Each unit cell consists of an emitter-coupled differential pair at the center, an input antenna which extends horizontally in both directions from the two base leads, an output antenna which extends vertically in both directions from the two collector leads, and high inductance bias lines. In operation, the active grid array is placed between a pair of crossed polarizers. The horizontally polarized input wave passes through the input polarizer and couples to the input leads. An amplified current then flows on the vertical leads, which radiate a vertically polarized amplified signal through the output polarizer. The polarizers serve dual functions, providing both input-output isolation as well as independent impedance matching for the input and output ports. The grid thus functions essentially as a free-space beam amplifier. Calculations indicate that output powers of several watts per square centimeter of grid area should be attainable with optimized structures

Boolean Query Reformulation with the Query Tree Classifier

One of the difficulties in using the current Boolean-based information retrieval systems is that it is hard for a user, especially a novice, to formulate an effective Boolean query. Query reformulation can be even more difficult and complex than formulation since the user can have difficulty in incorporating the new information gained from the previous search into his/her next query. In this research, query reformulation is viewed as a classification problem (i.e., classifying documents as either relevant or nonrelevant), and a new reformulation algorithm is proposed which builds a treestructured classifier (named the query tree) at each reformulation from a set of feedback documents retrieved from the previous search. The query tree can be easily transformed into a Boolean query. The query tree and two of the most important current query reformulation algorithms were compared on benchmark test sets (CACM. CISI, and MedJars). The query tree showed significant improvements over the current algorithms in most experiments. We attribute this improved performance to the ability of the query tree algorithm to select good search terms and to represent the relationships among search terms into a tree structure

Lanczos exact diagonalization study of field-induced phase transition for Ising and Heisenberg antiferromagnets

Using an exact diagonalization treatment of Ising and Heisenberg model Hamiltonians, we study field-induced phase transition for two-dimensional antiferromagnets. For the system of Ising antiferromagnet the predicted field-induced phase transition is of first order, while for the system of Heisenberg antiferromagnet it is the second-order transition. We find from the exact diagonalization calculations that the second-order phase transition (metamagnetism) occurs through a spin-flop process as an intermediate step.Comment: 4 pages, 4 figure