Seismic Fragility Analysis for Sheet Pile Wharves — Case Study of the Hualien Harbor in Taiwan

The seismic fragility curves represent the conditional probabilities that the structural damage meets or exceeds the specified damage states at various levels of the ground motion parameters, such as peak ground acceleration (PGA). In this study, the seismic fragility analysis for the sheet pile wharves of the Hualien Harbor in Taiwan was performed. The finite element analysis software PLAXIS was adopted for the nonlinear dynamic analysis. The time histories of several representative earthquake events that actually occurred in Taiwan, including the 1999 Chi-Chi Earthquake, were scaled to various PGA levels as the input motions. Then the seismic responses of the sheet pile wharves subjected to these earthquakes of different intensities were obtained. It is assumed that the maximum residual displacement at the top of the sheet pile wall is lognormal distributed. Thus, the conditional exceedance probabilities of each specified damage state at different levels of PGA were estimated according to the displacement threshold value of each damage state, and the fragility curves were deduced. Moreover, these fragility curves were parameterized assuming they can be well approximated by the lognormal cumulative probability function, which is important for the rapid estimation of earthquake loss

Interrelationships between public open space, common pool resources, publicness levels and commons dilemmas: a different perspective in urban planning

Public open space (POS) is central to the environment, and oftentimes spatial and architectural designs are emphasised in urban planning as part of creating quality POS. However, such initial design and planning of POS may not adequately encapsulate the sustainability dimensions of the complex social-ecological behavioural patterns of POS consumption and management, hence resulting in space mismanagement, underinvestment, and quality degradation. This phenomenon is particularly true and relevant in the context of government/state-owned POS. Therefore, an objective of this perspective paper, coupled with the concepts of the publicness levels, is to provide a different understanding of exclusivity and subtractibility natures of POS, primarily using the theory of common pool resources (CPRs), which subsequently helps explain and rationalise the perennial, adversarial POS management, quality and sustainability status quo. This paper reveals that, instead of being considered as pure public goods, scarce POS owns two inherent attributes of CPR, namely non-excludable and subtractive (rivalrous) that are ultimately susceptible to social/commons dilemmas, covering the Tragedy of the commons (overexploitation), management shirking, free-riding, underuse, disuse, and moral hazard, which lead to degraded, unsustainable POS. The commons or CPR theory can indeed offer a new paradigm shift, making urban planners and landscape managers to embrace that the unexclusive natures of CPR-based POS are truly finite and depletable and thus vulnerable to POS dilemmas. Hence, to achieve quality, sustainable POS commons, effective governance in terms of consumption and consistent management is vital. For future research, urban design as a necessary societal role is suggested, which has established the need for effective allocation of POS management via an adaptive institutional property rights design

Thrombolysis in Myocardial Infarction Frame Count in Single-Vessel Disease After Angioplasty

SUMMARYBackgroundWe compared the thrombolysis in myocardial infarction (TIMI) frame count and examined the impact of angioplasty on the count between patients with normal coronary angiograms and those with single-vessel disease (SVD).MethodsIn 780 consecutive patients referred for coronary angiography, TIMI frame count was measured for 149 patients who had SVD and 32 patients with normal angiograms who underwent the procedure for electro-physiologic study or valvular heart disease survey.ResultsComparison of each of the three vessels in the normal vessel group with the corresponding non-stenotic vessels in the SVD group showed similar counts in each of the left anterior descending artery (LAD), left circumflex artery (LCX), and right coronary artery (RCA). For the stenotic vessels, after successful angioplasty, the counts were all reduced (LAD, 54.5 ±28.8 vs. 34.0 ±19.3; LCX, 67.3 ±31.1 vs. 34.1 ±19.0; RCA, 33.2 ±28.1 vs. 19.3 ±7.9; all p <0.05). In addition, the count in the RCA after angioplasty was lower, compared with the RCA of the normal group (19.3 ±7.9 vs. 29.1 ±14.6, p = 0.001). Multivariate analysis showed that the use of oral calcium channel blockers was the only independent predictor for the reduction in RCA after angioplasty.ConclusionIn patients with SVD, the data of TIMI frame count in the nonstenotic vessels were similar to those without the disease, suggesting that the count in the normal artery is not affected by the adjacent stenotic artery. For the stenotic vessels, angioplasty had differential effects on each of the three arteries, indicating the existence of distinct properties, which is affected by calcium channel blockers, for individual coronary arteries in response to atherosclerosis and/or angioplasty

Preparation, characterization, and application of titanium nano-tube array in dye-sensitized solar cells

The vertically orientated TiO2 nanotube array (TNA) decorated with TiO2 nano-particles was successfully fabricated by electrochemically anodizing titanium (Ti) foils followed by Ti-precursor post-treatment and annealing process. The TNA morphology characterized by SEM and TEM was found to be filled with TiO2 nano-particles interior and exterior of the TiO2 nano-tubes after titanium (IV) n-butoxide (TnB) treatment, whereas TiO2 nano-particles were only found inside of TiO2 nano-tubes upon titanium tetrachloride (TiCl4) treatment. The efficiency in TNA-based DSSCs was improved by both TnB and TiCl4 treatment presumably due to the increase of dye adsorption

QoS routing with link stability in mobile ad hoc networks

Abstract. In this paper, in accordance with requirements of different users and supplying effective usage of limited network resources, we propose a stable QoS routing mechanism to determine a guaranteed route suited for mobile ad hoc wireless networks. The manner exploits the received signal strength (RSS) techniques to estimate the distance and the signal change of the velocity to evaluate the breakaway. To ensure the QoS it chooses a steady path from the source to the destination and tries to reserve the bandwidth. Ultimately, it is clear to find that the performance never decrease even the growth of the overhead and the movement of users via the simulated by ns-2. Introduction Mobile Ad Hoc Wireless Networks (MANET), also called the Ad hoc network, is lots of moving nodes (mobile hosts) communicating with their adjacent mobile node by radio wave. Every node can contact each other without existence infrastructural network. In the Ad hoc network, it differs from cellular wireless networks that need base stations to deliver and receive the packets. Each node plays the role as a router. When one of them wants to deliver packets to destination out of its coverage, intermediate nodes will forward this packet to the next node till the destination node receive it. In traditional cellular wireless networks, generally we need to establish base stations in advance. Fixed nodes far and near connect to the backbone and become a wireless network environment. In this network the customer who wants to communicate with another must locate in the base station coverage. If user moved out of base station&apos;s service scope, he can&apos;t take the communication. Consequently, we need to establish enough base stations to achieve the objective. Ad hoc networks do not demand fixed network infrastructures and centralized management mechanisms, as well as can be built anytime, anywhere rapidly. Ad hoc networks also have the feature of self-creating, self-organization and elf-management as well as deploy and remove network easily. Ad hoc network has above advantages. However, the Ad hoc network environment has the following restricts [1], including of Network topology instable, Limited energy constrained and Limited network bandwidth-constrained QoS Routing with Link Stability in Mobile A

Neuroprotective Effect of Paeonol Mediates Anti-Inflammation via Suppressing Toll-Like Receptor 2 and Toll-Like Receptor 4 Signaling Pathways in Cerebral Ischemia-Reperfusion Injured Rats

Paeonol is a phenolic compound derived from Paeonia suffruticosa Andrews (MC) and P. lactiflora Pall (PL). Paeonol can reduce cerebral infarction volume and improve neurological deficits through antioxidative and anti-inflammatory effects. However, the anti-inflammatory pathway of paeonol remains unclear. This study investigated the relationship between anti-inflammatory responses of paeonol and signaling pathways of TLR2 and TLR4 in cerebral infarct. We established the cerebral ischemia-reperfusion model in Sprague Dawley rats by occluding right middle cerebral artery for 60 min, followed by reperfusion for 24 h. The neurological deficit score was examined, and the brains of the rats were removed for cerebral infarction volume and immunohistochemistry (IHC) analysis. The infarction volume and neurological deficits were lower in the paeonol group (pretreatment with paeonol; 20 mg/kg i.p.) than in the control group (without paeonol treatment). The IHC analysis revealed that the number of TLR2-, TLR4-, Iba1-, NF-κB- (P50-), and IL-1β-immunoreactive cells and TUNEL-positive cells was significantly lower in the paeonol group; however, the number of TNF-α-immunoreactive cells did not differ between the paeonol and control groups. The paeonol reveals some neuroprotective effects in the model of ischemia, which could be due to the reduction of many proinflammatory receptors/mediators, although the mechanisms are not clear

Substrate Specificity and Plasticity of FERM-Containing Protein Tyrosine Phosphatases

SummaryEpidermal growth factor receptor (EGFR) pathway substrate 15 (Eps15) is a newly identified substrate for protein tyrosine phosphatase N3 (PTPN3), which belongs to the FERM-containing PTP subfamily comprising five members including PTPN3, N4, N13, N14, and N21. We solved the crystal structures of the PTPN3-Eps15 phosphopeptide complex and found that His812 of PTPN3 and Pro850 of Eps15 are responsible for the specific interaction between them. We defined the critical role of the additional residue Tyr676 of PTPN3, which is replaced by Ile939 in PTPN14, in recognition of tyrosine phosphorylated Eps15. The WPD loop necessary for catalysis is present in all members but not PTPN21. We identified that Glu instead of Asp in the WPE loop contributes to the catalytic incapability of PTPN21 due to an extended distance beyond protonation targeting a phosphotyrosine substrate. Together with in vivo validations, our results provide novel insights into the substrate specificity and plasticity of FERM-containing PTPs

Partial Nephrectomy in the Treatment of Localized Renal Cell Carcinoma — Experience of Taichung Veterans General Hospital

BackgroundPartial nephrectomy has been considered an effective and efficient method in the treatment of localized renal cell carcinoma. Herein, we retrospectively review our experience with partial nephrectomy in the treatment of localized renal cell carcinoma and compared it with patients who received radical nephrectomy.MethodsFrom 1982 to 2005, 35 patients who received partial nephrectomy for localized renal cell carcinoma were enrolled in this study. Ten patients were female (28.6%). The median age was 70 years (range, 42–82 years). Sixteen (45.7%) patients had pathologic T1a tumors; 17 (48.6%) patients had pathologic T1b tumors and 2 (5.7%) patients had pathologic T2 tumor (7 cm). In the meantime, 128 patients who had T1N0M0 renal cell carcinoma and who received radical nephrectomy were assigned to a control group. Thirty-nine patients (30.5%) were female in this group. The median age was 62 years (range, 30–83 years). The tumor characteristics, location, surgical techniques and patient survival were subsequently compared.ResultsThe median tumor size in the partial nephrectomy group was 3.9 cm (range, 1.5–7.0 cm), and it was 4.5 cm (range, 1–6.5 cm) in radical nephrectomy group. The tumor size was smaller in the partial nephrectomy group (p = 0.003). The median follow-up period was 4.38 years (range, 0.05–17.99 years) in the partial nephrectomy group and 5.66 years (range, 0.01–22.25 years) in the radical nephrectomy group. There was no local recurrence or distant metastasis in the partial nephrectomy group. The 5-year overall survival was 85.0% compared with 91.4% in the radical nephrectomy group (p = 0.126). The 5-year disease-specific survival in the partial nephrectomy group was 100%. The postoperative serum creatinine level increased to > 2.0 mg/dL in 5 (14.3%) patients in the partial nephrectomy group, but no patient needed hemodialysis during follow-up.ConclusionFrom our review, partial nephrectomy is safe and provides excellent disease control in the treatment of localized renal cell carcinoma in selected patients. Renal function preservation was observed in the partial nephrectomy group, while the operated kidney showed functioning in the follow-up nuclear medicine survey