Identifying the Service Quality for a B2B Cross-Border E-Commerce Platform

The global cross-border e-commerce (CBEC) transactions is experiencing a fast development in recent years. However, the academic research is still rare. In addition, service quality of the CBEC platforms have been identified as the important factors of the success of CBEC but there is a lack of empirical work to identify the service quality of the business to business (B2B) CBEC platforms are rare. To fulfill this gap, this study intends to identify the critical service quality of the B2B CBEC platform. Based on the service quality model, we will identify the critical service quality of the B2B CBEC platform. We will conduct a modified Delphi method to collect data with the experts and suppliers in the platform. Our research findings will contribute to the academia by creating a service quality model of B2B CBEC platform. The results will provide practical insights for the platform design of B2B CBEC platform

Paving the Way for Digital Transformation: Investigate Customer Experiences of Using Mobile Apps

Background: Mobile apps have become a critical channel for retailers to interact with their customers and digitalize shopping behaviors in the customer journeys. In the transition of digital transformation, convenience stores have launched mobile apps to interact with and particularly collecting data from their customers. It is critical to investigate customer experiences in using mobile apps because it paves the way for successful digital transformation. This paper aims to investigate the customer experiences of convenience stores’ mobile apps from the online reviews. Method: This study proposed a mobile apps quality model as the theoretical framework to empirically test the online reviews of mobile apps. Large volumes of online reviews generated by customers provide important strategic values for business and service design for mobile apps. This paper collected 40,521 online reviews of two leading convenience stores in Taiwan and analyzed with text analysis and qualitative analysis. Results: Applying text analysis and qualitative analysis, this paper identified the critical quality attributes of mobile apps in the convenience stores that need to be improved. In addition, software quality is the major concern that 7-11 Open Point needs to improve, followed by service quality and information quality respectively. Software quality is also the major concern that FamilyMart app needs to improve the customer experiences, followed by service quality and information quality. Moreover, customer dissatisfaction primarily resulted from problems in software quality and information quality. Instead, convenience, ease of use, and practicability of mobile apps lead to customer satisfaction. Conclusion: The results demonstrate that software quality, information quality, and service quality are critical dimensions in affecting customer experiences in using mobile apps. Although different mobile apps may have different priorities of quality attributes that are needed to be improved, these improvements of mobile apps help to enhance customer experiences and accelerate digital transformation of the convenience stores

Application of AHP hierarchical analysis and KANO quality model to investigate the needs of eye drop users and the charm factor of the compliance aids design

Previous studies have indicated that many patients with eye diseases are not adherent to eyedrops due to the difficulty in administration. The purpose of using eyedrop compliance aids is to help patients who have difficulties in administering eyedrops. However, this method has not been well recognized and accepted. This study aimed to upgrade eyedrop compliance aids so that the adherence of eyedrop users could be improved. Among the research methods employed in this study, the analytic hierarchy process (AHP) helped in proposing the best function sequence of the device, and a questionnaire based on the Kano model helped understand the degree of satisfaction with the existing products, as well as discover the appealing factors of their functions and examine their functional relationships. Finally, the results of the two methods were discussed and compared, and the results were used to identify the basic appealing factors influencing consumer satisfaction as well as provide the element attributes and significant features to be weighed in the design of eyedrops. This study suggested that in the design of eyedrops, both the physical and psychological needs of users should be taken into consideration, and reference indexes for aids design that may effectively improve user adherence to eyedrops should be proposed

THE IMPACT OF SOCIAL PSYCHOLOGICAL FACTORS ON THE RELATIONSHIP QUALITY OF FACEBOOK USERS

Armed with the great potential for business value and social networking, social media have generated great interests in academia and practice. Rare studies investigated the impact of social psychological factors on the usage of Facebook and the formation of quality relationship. The objective of this paper is to examine the key social psychological factors to better explain the formation of quality relationship. Our proposed theoretical model combined the theories of social influence, social identity, and social presence to capture the essences of the relationship quality between users and Facebook. We conducted a survey to collect data and empirically test our proposed model. Overall, our findings provide theoretical insights to explain the influence of social psychological factors on the usage of Facebook and quality relationship. These findings also help practitioners to plan marketing strategies in better utilize social network sites

Discovery of serum biomarkers of alcoholic fatty liver in a rodent model: C-reactive protein

<p>Abstract</p> <p>Background</p> <p>Excessive consumption of alcohol contributes to alcoholic liver disease. Fatty liver is the early stage of alcohol-related liver disease. The aim of this study was to search for specific serological biomarkers of alcoholic fatty liver (AFL) compared to healthy controls, non-alcoholic fatty liver (NAFL) and liver fibrosis in a rodent model.</p> <p>Methods</p> <p>Serum samples derived from animals with AFL, NAFL, or liver fibrosis were characterized and compared using two-dimensional differential gel electrophoresis. A matrix-assisted laser desorption ionization-time of flight tandem mass spectrometer in conjunction with mascot software was used for protein identification. Subsequently, Western blotting and flexible multi-analyte profiling were used to measure the expressions of the putative biomarkers present in the serum of animals and clinical patients.</p> <p>Results</p> <p>Eight differential putative biomarkers were identified, and the two most differentiated proteins, including upregulated C-reactive protein (CRP) and downregulated haptoglobin (Hp), were further investigated. Western blotting validated that CRP was dramatically higher in the serum of AFL compared to healthy controls and other animals with liver disease of NAFL or liver fibrosis (<it>p </it>< 0.05). Moreover, we found that CRP and Hp were both lower in liver fibrosis of TAA-induced rats and clinical hepatitis C virus-infected patients.</p> <p>Conclusion</p> <p>The results suggest that increased levels of CRP are an early sign of AFL in rats. The abnormally elevated CRP induced by ethanol can be used as a biomarker to distinguish AFL from normal or otherwise diseased livers.</p

The Sac1 Lipid Phosphatase Regulates Cell Shape Change and the JNK Cascade during Dorsal Closure in Drosophila

AbstractThe Sac1 lipid phosphatase dephosphorylates several phosphatidylinositol (PtdIns) phosphates and, in yeast, regulates a diverse range of cellular processes including organization of the actin cytoskeleton and secretion [1]. We have identified mutations in the gene encoding Drosophila Sac1. sac1 mutants die as embryos with defects in dorsal closure (DC). DC involves the migration of the epidermis to close a hole in the dorsal surface of the embryo occupied by the amnioserosa. It requires cell shape change in both the epidermis and amnioserosa and activation of a Jun N-terminal kinase (JNK) MAPK cascade in the leading edge cells of the epidermis [2]. Loss of Sac1 leads to the improper activation of two key events in DC: cell shape change in the amnioserosa and JNK signaling. sac1 interacts genetically with other participants in these two events, and our data suggest that loss of Sac1 leads to upregulation of one or more signals controlling DC. This study is the first report of a role for Sac1 in the development of a multicellular organism

Identification of overexpressed cytokines as serum biomarkers of hepatitis C virus-induced liver fibrosis using bead-based flexible multiple analyte profiling

Hepatic inflammation is the stimulator to activate hepatic stellate cells (HSCs) and triggers fibrogenesis. Cytokines are produced during liver inflammation and maybe considered as liver fibrosis biomarker. The aim of this study was to investigate whether cytokines can be used as reliable biomarkers of liver fibrosis using flexible multi-analyte profiling (xMAP). A total of 61 chronic hepatitis C patients with different severity of liver fibrosis were enrolled. Liver biopsy was used as standard to assess the severity of fibrosis according to METAVIR classification. Afterward, 15 samples from healthy controls were analyzed and totally 50 cytokines were screened using flexible multi-analyte profiling to discover differential biomarkers. Finally, levels of protein expressions of individual stages of liver fibrosis were measured. In histological examination, the necroinflammatory score (histology activity index, HAI) was increased from F1 to F4 stage in hepatitis C virus (HCV) infected patients, indicating that inflammation was accompanied with the progression of liver fibrosis. Using flexible multi-analyte profiling, four serum cytokines, including IFN-α2 (p=0.023), GRO-α (p=0.013), SCF (p=0.047) and SDF-1α p=0.024), were identified under antibody specific recognition and elevated with HAI score. This study reveals the relationship between cytokines and liver fibrosis, and demonstrated that IFN-α2, GRO-α, SCF and SDF-1 α may be used as biomarkers to predict liver fibrosis. The overexpressed cytokines may play a role in the progression of liver fibrosis and deserves further investigation.Keywords: Cytokine, flexible multi-analyte profiling, hepatitis C virus, liver fibrosisAfrican Journal of Biotechnology Vol. 11(29), pp. 7535-7541, 29 April, 201