2 research outputs found
A General Scavenging Rate Constant for Reaction of Hydroxyl Radical with Organic Carbon in Atmospheric Waters
Hydroxyl radical (OH) is an important
oxidant in atmospheric aqueous
phases such as cloud and fog drops and water-containing aerosol particles.
We find that numerical models nearly always overestimate aqueous hydroxyl
radical concentrations because they overpredict its rate of formation
and, more significantly, underpredict its sinks. To address this latter
point, we examined OH sinks in atmospheric drops and aqueous particles
using both new samples and an analysis of published data. Although
the molecular composition of organic carbon, the dominant sink of
OH, is extremely complex and poorly constrained, this sink behaves
very similarly in different atmospheric waters and even in surface
waters. Thus, the sink for aqueous OH can be estimated as the concentration
of dissolved organic carbon multiplied by a general scavenging rate
constant [<i>k</i><sub>C,OH</sub> = (3.8 ± 1.9) ×
10<sup>8</sup> L (mol C)<sup>−1</sup> s<sup>–1</sup>], a simple process that should significantly improve estimates of
OH concentrations in atmospheric drops and aqueous particles
Sensory systems and ionocytes are targets for silver nanoparticle effects in fish
<p>Some nanoparticles (NPs) may induce adverse health effects in exposed organisms, but to date the evidence for this in wildlife is very limited. Silver nanoparticles (AgNPs) can be toxic to aquatic organisms, including fish, at concentrations relevant for some environmental exposures. We applied whole mount <i>in-situ</i> hybridisation (<i>WISH</i>) in zebrafish embryos and larvae for a suite of genes involved with detoxifying processes and oxidative stress, including metallothionein (<i>mt2</i>), glutathionine <i>S</i>-transferase pi (<i>gstp</i>), glutathionine <i>S</i>-transferase mu (<i>gstm1</i>), haem oxygenase (<i>hmox1</i>) and ferritin heavy chain 1 (<i>fth1</i>) to identify potential target tissues and effect mechanisms of AgNPs compared with a bulk counterpart and ionic silver (AgNO<sub>3</sub>). AgNPs caused upregulation in the expression of <i>mt2, gstp</i> and <i>gstm1</i> and down regulation of expression of both <i>hmox1</i> and <i>fth1</i> and there were both life stage and tissue-specific responses. Responding tissues included olfactory bulbs, lateral line neuromasts and ionocytes in the skin with the potential for effects on olfaction, behaviour and maintenance of ion balance. Silver ions induced similar gene responses and affected the same target tissues as AgNPs. AgNPs invoked levels of target gene responses more similar to silver treatments compared to coated AgNPs indicating the responses seen were due to released silver ions. In the <i>Nrf2</i> zebrafish mutant, expression of <i>mt2</i> (24 hpf) and <i>gstp</i> (3 dpf) were either non-detectable or were at lower levels compared with wild type zebrafish for exposures to AgNPs, indicating that these gene responses are controlled through the Nrf2-Keap pathway.</p