43 research outputs found
Cerebrovascular Disease; A Leading Cause of Epilepsy
Various types of cerebrovascular diseases can result in epilepsy in any age, especially in the elderly. Besides well-known cause of epilepsy as large cerebral infarction involving cerebral cortex and intracerebral hemorrhage, there are growing evidences of roles of subcortical infarction, chronic subdural hematoma, and superficial siderosis of the central nervous system in the pathogenesis of epilepsy. We review here the epidemiology and possible predictors of epilepsy in each type of cerebrovascular lesions and summarize the characteristics of semiology and electroencephalography findings in order to take early treatment strategy. Additionally, relevance of acute-symptomatic seizures and status epilepticus to epilepsy is discussed
Endoscopic Resection of Zenker's Diverticulum
We report an endoscopically assisted total diverticulectomy
for Zenker's diverticulum. Skin incisions were made at the
anterior axillary line, the center of the sternum, and the neck as
portals for endoscopical instruments. The skin was retracted with
hooks which provided an excellent view of the working space. The
diverticulum was fully exposed and resected by using a multifire
endoscopic stapler. This approach is minimally invasive in
comparison with the conventional open cervical approach
Two cases of hard metal lung disease showing gradual improvement in pulmonary function after avoiding dust exposure
Epidemiological and clinical features of lung cancer patients from 1999 to 2009 in Tokushima Prefecture of Japan
Lung cancer is the leading cause of malignancy-related death worldwide. In
the present study, we reviewed the epidemiologic and clinical features of lung cancer in
Tokushima Prefecture, Japan. Between January 1999 and December 2009, 2,183 patients
with lung cancer were enrolled in this study. One thousand five hundred ninety-one (73%)
patients were male and 592 (27%) patients were female. Median age was 70 years, with a
range of 15-93 years. Seventy-six percent of patients had smoking history. One thousand
nine hundred five (87%) patients were non-small cell lung cancer and the predominant histological
type was adenocarcinoma (51%). Among all 2,183 patients, 702 (32%) belonged to
elderly population. Four hundred seventy-one (22%), 213 (10%), 24 (1%), 116 (5%), 238 (11%),
370 (17%) and 678 (31%) patients had stage IA, IB, IIA, IIB, IIIA, IIIB and IV lung cancer, respectively.
In Tokushima University Hospital, 516 (29%), 191 (11%), 58 (3%), 755 (43%) and
216 (12%) patients were initially treated with chemotherapy, chemo-radiotherapy, thoracic
radiotherapy, operation and best supportive care, respectively. The median time to
progression (TTP) and the median survival time (MST) of patients treated with chemotherapy
and chemo-radiotherapy were 3.5 months, 13.0 months and 7.0 months, 18.0 months,
respectively. The median TTP and the MST of 33 elderly patients treated with chemotherapy
were 3.3 months and 18.0 months, respectively, which were comparable with those of
total population. These results indicated the benefit of chemotherapy in elderly patients
with advanced lung cancer by proper selection
Good Death of Dying Elderly Patients with and without Comorbid Dementia from the Perspective of Bereaved Family Members
Psychological Distress among Caregivers for Patients Who Die of Cancer: A Preliminary Study in Japan
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