Enhanced Electric Double-Layer Capacitance by Desolvation of Lithium Ions in Confined Nanospaces of Microporous Carbon

Carbon electrodes with specific microporous structures are strongly desired to improve the performance of electric double-layer capacitors (EDLCs). We report solvated states of Li ions in confined carbon micropores affecting specific capacitance. The average Li⁺ solvation number of 1 M LiClO₄/propylene carbonate (PC) electrolyte introduced into porous carbon electrodes was determined using Raman spectroscopy and ⁷Li NMR. Micropores with slightly larger pore size against the solvated molecules and the narrow two-dimensional spaces decreased the solvation number, enhancing specific capacitance. Hence, specific carbon morphology may be related to high EDL capacitance, and micropore structure is important in obtaining highly capacitive EDLC materials

Hidden Markov model analysis reveals the advantage of analytic eye movement patterns in face recognition across cultures

miRNA profiles of the RA patients with ILD. Average values of each group are shown. Standard deviations are shown in parenthesis. Difference were tested between bDMARDs(+) and bDMARDs(−) by Mann-Whitney’s U test. RA: rheumatoid arthritis, ILD(+)RA: ILD positive RA. (DOCX 15 kb

Additional file 6: Table S5. of Plasma miRNA expression profiles in rheumatoid arthritis associated interstitial lung disease

miRNA profiles of the RA patients with ILD. Average values of each group are shown. Standard deviations are shown in parenthesis. Difference were tested between bDMARDs(+) and bDMARDs(−) by Mann-Whitney’s U test. RA: rheumatoid arthritis, ILD(+)RA: ILD positive RA. (DOCX 15 kb

Additional file 5: Table S4. of Plasma miRNA expression profiles in rheumatoid arthritis associated interstitial lung disease

miRNA profiles of the RA patients with ILD. Average values of each group are shown. Standard deviations are shown in parenthesis. Difference were tested between DAS28 < 4.0 and DAS28 ≧ 4.0 by Mann-Whitney’s U test. RA: rheumatoid arthritis, ILD(+)RA: ILD positive RA. (DOCX 15 kb

Biomarker for nontuberculous mycobacterial pulmonary disease in patients with rheumatoid arthritis: Anti-glycopeptidolipid core antigen immunoglobulin A antibodies

<p><b>Objective:</b> Nontuberculous mycobacterial (NTM) pulmonary disease is occasionally associated with rheumatoid arthritis (RA), influencing the therapeutic strategy of RA. Since chronic lung diseases are frequently associated with RA, the diagnosis of NTM pulmonary disease is quite difficult in RA patients. Recently, a serological diagnostic test detecting serum immunoglobulin A against the glycopeptidolipid (GPL) core antigen was developed. We investigated the serum levels of anti-GPL antibodies in RA patients to determine the usefulness for detecting NTM pulmonary disease.</p> <p><b>Methods:</b> Anti-GPL antibodies were detected in the sera from RA patients with or without NTM pulmonary disease.</p> <p><b>Results:</b> The positivity of anti-GPL antibodies in RA patients with NTM pulmonary disease was higher than in RA without (<i>p</i> = 1.76 × 10⁻¹⁴, odds ratio 70.29, 95% confidence interval [CI] 22.28–221.83). Anti-GPL Ab titers were increased in RA with NTM pulmonary disease (mean titer ± standard deviation [U/ml], RA with NTM pulmonary disease: 4.1 ± 7.0, RA without NTM pulmonary disease: 0.4 ± 1.6, <i>p</i> = 1.51 × 10⁻¹⁰). The area under the curve (AUC) value of the receiver operating characteristic (ROC) curve for anti-GPL antibodies was 0.917 (95%CI 0.860–0.974, <i>p</i> = 3.32 × 10⁻⁴⁷).</p> <p><b>Conclusions:</b> Serum anti-GPL antibodies are useful for detecting NTM pulmonary disease in RA patients.</p

LIPS for gAChR in the sera from AIH patients with or without HLA-DRB1 *0403 allele.

<p>We tested the sera from AIH patients with or without HLA-DRB1 *0403 allele. The mean anti-gAChR α3 antibody level in patient with *0403 allele was 1.06 antibody index (AI), which was significantly higher than in those without *0403 allele with a mean level of 0.59 A.I. (<i>p</i> = 0.043). The mean anti-gAChR β4 antibody level in patients with *0403 allele was 0.76A.I, which was significantly higher than in the mean level of 0.50A.I. in those without *0403 allele (<i>p</i> = 0.010).</p

Relationship between anti-gAChR α3 and anti- gAChR β4 antibody levels.

<p>Calculation of the correlation between anti-gAChR α3 and anti-gAChR β4 antibody levels in AIH patients with both autoantibodies (n = 17). Correlation was calculated using Spearman’s Rank Correlation test. There is no correlation at all (r = -0.04, <i>p</i> = 0.58).</p

<i>HLA-DRB1</i> allele frequencies in Japanese patients with MPO-AAV or PR3-AAV or in healthy controls.

<p><i>HLA-DRB1</i> allele frequencies in Japanese patients with MPO-AAV or PR3-AAV or in healthy controls.</p

<i>HLA-DRB1</i> allele frequencies in Japanese patients with MPA, EGPA, or GPA or in healthy controls.

<p><i>HLA-DRB1</i> allele frequencies in Japanese patients with MPA, EGPA, or GPA or in healthy controls.</p

<i>HLA-DPB1</i> allele frequencies in Japanese patients with MPO-AAV or PR3-AAV or in healthy controls.

<p><i>HLA-DPB1</i> allele frequencies in Japanese patients with MPO-AAV or PR3-AAV or in healthy controls.</p