Prevalence and socio-demographic factors affecting anaemia in pregnant women of Dibrugarh District, Assam, India

Background: Anaemia is the most common nutritional deficiency observed globally. Anaemia worsens during pregnancy leading to adverse maternal and fetal outcome. Dibrugarh district has the highest maternal mortality in the country, one of the major factor being anaemia during pregnancy. Aims & Objectives: To assess the prevalence and socio-demographic determinants of anaemia in pregnant women of Dibrugarh District. Material & Methods: A community based, cross-sectional study was conducted in a block selected randomly. Study period was for the period from May’2015 to February’2016. Study sample included 290 participants. Results: Prevalence of anaemia among study participants was found to be 73.1%. (Mild 10%, moderate 43.1 % and severe 20%). Mean haemoglobin of study subjects was 9.07±2.26 g/dl. Average age of the study subjects was 23.24±4. Majority (27.2%) had their education upto primary school level and belong to class IV socioeconomic status. Univariate analysis and multiple logistic regression analysis shows educational qualification, socioeconomic status and type of housing are statistically associated with anaemia during pregnancy. Conclusion: Anaemia is rampant in the community needing urgent action to prevent morbidity amongst both mother and chil

PREVALENCE OF DIARRHOEA AMONG UNDER-FIVE CHILDREN AND HEALTH SEEKING BEHAVIOUR OF THEIR MOTHERS IN SLUMS OF DIBRUGARH TOWN, ASSAM

*Author for Correspondence Introduction: The under five mortality continues to rise globally at an annual rate of 24 % despite efforts to counteract it through vertical programmes. Seven out of ten child deaths are due to diarrhoea, acute respiratory infections, measles and malnutrition. In Indian slums nearly 100,000 babies die every year before their fifth birthday. Poor nutrition and health-seeking behaviour, poor environmental conditions and resultant high prevalence of infectious diseases contribute to the high child morbidity and mortality among the urban poor. Objectives: To fin

Design of “Click” Fluorescent Labeled 2′-deoxyuridines via C5-[4-(2-Propynyl(methyl)amino)]phenyl Acetylene as a Universal Linker: Synthesis, Photophysical Properties, and Interaction with BSA

Microenvironment-sensitive fluorescent nucleosides present attractive advantages over single-emitting dyes for sensing inter-biomolecular interactions involving DNA. Herein, we report the rational design and synthesis of triazolyl push–pull fluorophore-labeled uridines via the intermediacy of C5-[4-(2-propynyl­(methyl)­amino)]­phenyl acetylene as a universal linker. The synthesized nucleosides showed interesting solvatochromic characteristic and/or intramolecular charge transfer (ICT) features. A few of them also exhibited dual-emitting characteristics evidencing our designing concept. The HOMO–LUMO distribution showed that the emissive states of these nucleosides were characterized with more significant electron redistribution between the C5-[4-(2-propynyl­(methyl)­amino)]­phenyl triazolyl donor moiety and the aromatic chromophores linked to it, leading to modulated emission property. The solvent polarity sensitivity of these nucleosides was also tested. The synthesized triazolyl benzonitrile (<b>10C</b>), naphthyl (<b>10E</b>), and pyrenyl (<b>10G</b>) nucleosides were found to exhibit interesting ICT and dual (LE/ICT) emission properties. The dual-emitting pyrenyl nucleoside maintained a good ratiometric response in the BSA protein microenvironment, enabling the switch-on ratiometric sensing of BSA as the only protein biomolecule. Thus, it is expected that the new fluorescent nucleoside analogues would be useful in designing DNA probes for nucleic acid analysis or studying DNA–protein interactions via a drastic change in fluorescence response due to a change in micropolarity