3,063 research outputs found
Stress dependent thermal pressurization of a fluid-saturated rock
Temperature increase in saturated porous materials under undrained conditions
leads to thermal pressurization of the pore fluid due to the discrepancy
between the thermal expansion coefficients of the pore fluid and of the solid
matrix. This increase in the pore fluid pressure induces a reduction of the
effective mean stress and can lead to shear failure or hydraulic fracturing.
The equations governing the phenomenon of thermal pressurization are presented
and this phenomenon is studied experimentally for a saturated granular rock in
an undrained heating test under constant isotropic stress. Careful analysis of
the effect of mechanical and thermal deformation of the drainage and pressure
measurement system is performed and a correction of the measured pore pressure
is introduced. The test results are modelled using a non-linear
thermo-poro-elastic constitutive model of the granular rock with emphasis on
the stress-dependent character of the rock compressibility. The effects of
stress and temperature on thermal pressurization observed in the tests are
correctly reproduced by the model
Two Novel Adenoviruses in Free-Living British lizards
In this study, we describe two novel adenoviruses isolated from (i) a common lizard (Zootoca vivipara) found dead and examined post-mortem and (ii) pooled samples from free-living sand lizards (Lacerta agilis agilis). Sequencing indicated the two were closely related atadenovirus strains which were distinct from previously recorded adenoviruses in lizards. Adenoviruses are not always associated with disease in squamates, but morbidity and mortality have been reported. These are the first known cases of adenovirus infection in free-living native British lizards, and further monitoring will be necessary to elucidate the implications of these possible pathogens for vulnerable populations of native reptiles
Room temperature plasmon laser by total internal reflection
Plasmon lasers create and sustain intense and coherent optical fields below
light's diffraction limit with the unique ability to drastically enhance
light-matter interactions bringing fundamentally new capabilities to
bio-sensing, data storage, photolithography and optical communications.
However, these important applications require room temperature operation, which
remains a major hurdle. Here, we report a room temperature semiconductor
plasmon laser with both strong cavity feedback and optical confinement to
1/20th of the wavelength. The strong feedback arises from total internal
reflection of surface plasmons, while the confinement enhances the spontaneous
emission rate by up to 20 times.Comment: 8 Page, 2 Figure
Escherichia coli induces apoptosis and proliferation of mammary cells
Mammary cell apoptosis and proliferation were assessed after injection of Escherichia coli into the left mammary quarters of six cows. Bacteriological analysis of foremilk samples revealed coliform infection in the injected quarters of four cows. Milk somatic cell counts increased in these quarters and peaked at 24 h after bacterial injection. Body temperature also increased, peaking at 12 h postinjection, The number of apoptotic cells was significantly higher in the mastitic tissue than in the uninfected control. Expression of Bax and interleukin-1 beta converting enzyme increased in the mastitic tissue at 24 h and 72 h postinfection, whereas Bcl-2 expression decreased at 24 h but did not differ significantly from the control at 72 h postinfection, Induction of matrix metalloproteinase-g, stromelysin-1 and urokinase-type plasminogen activator was also observed in the mastitic tissue. Moreover, cell proliferation increased in the infected tissue, These results demonstrate that Escherichia coli-induced mastitis promotes apoptosis and cell proliferation
The multicovering radius problem for some types of discrete structures
The covering radius problem is a question in coding theory concerned with
finding the minimum radius such that, given a code that is a subset of an
underlying metric space, balls of radius over its code words cover the
entire metric space. Klapper introduced a code parameter, called the
multicovering radius, which is a generalization of the covering radius. In this
paper, we introduce an analogue of the multicovering radius for permutation
codes (cf. Keevash and Ku, 2006) and for codes of perfect matchings (cf. Aw and
Ku, 2012). We apply probabilistic tools to give some lower bounds on the
multicovering radii of these codes. In the process of obtaining these results,
we also correct an error in the proof of the lower bound of the covering radius
that appeared in Keevash and Ku (2006). We conclude with a discussion of the
multicovering radius problem in an even more general context, which offers room
for further research.Comment: To appear in Designs, Codes and Cryptography (2012
Detecting a conditional extrme value model
In classical extreme value theory probabilities of extreme events are
estimated assuming all the components of a random vector to be in a domain of
attraction of an extreme value distribution. In contrast, the conditional
extreme value model assumes a domain of attraction condition on a
sub-collection of the components of a multivariate random vector. This model
has been studied in
\cite{heffernan:tawn:2004,heffernan:resnick:2007,das:resnick:2008a}.
In this paper we propose three statistics which act as tools to detect this
model in a bivariate set-up. In addition, the proposed statistics also help to
distinguish between two forms of the limit measure that is obtained in the
model.Comment: 21 pages, 4 figure
R-process enrichment from a single event in an ancient dwarf galaxy
Elements heavier than zinc are synthesized through the (r)apid and (s)low
neutron-capture processes. The main site of production of the r-process
elements (such as europium) has been debated for nearly 60 years. Initial
studies of chemical abundance trends in old Milky Way halo stars suggested
continual r-process production, in sites like core-collapse supernovae. But
evidence from the local Universe favors r-process production mainly during rare
events, such as neutron star mergers. The appearance of a europium abundance
plateau in some dwarf spheroidal galaxies has been suggested as evidence for
rare r-process enrichment in the early Universe, but only under the assumption
of no gas accretion into the dwarf galaxies. Cosmologically motivated gas
accretion favors continual r-process enrichment in these systems. Furthermore,
the universal r-process pattern has not been cleanly identified in dwarf
spheroidals. The smaller, chemically simpler, and more ancient ultra-faint
dwarf galaxies assembled shortly after the first stars formed, and are ideal
systems with which to study nucleosynthesis events such as the r-process.
Reticulum II is one such galaxy. The abundances of non-neutron-capture elements
in this galaxy (and others like it) are similar to those of other old stars.
Here, we report that seven of nine stars in Reticulum II observed with
high-resolution spectroscopy show strong enhancements in heavy neutron-capture
elements, with abundances that follow the universal r-process pattern above
barium. The enhancement in this "r-process galaxy" is 2-3 orders of magnitude
higher than that detected in any other ultra-faint dwarf galaxy. This implies
that a single rare event produced the r-process material in Reticulum II. The
r-process yield and event rate are incompatible with ordinary core-collapse
supernovae, but consistent with other possible sites, such as neutron star
mergers.Comment: Published in Nature, 21 Mar 2016:
http://dx.doi.org/10.1038/nature1742
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