Community health workers as change agents in improving equity in birth outcomes in Detroit

We examined whether pairing pregnant women with community health workers improved pregnancy outcomes among 254 Black women with singleton pregnancies participating in the Women-Inspired Neighborhood (WIN) Network: Detroit using a case-control design. A subset (N = 63) of women were recontacted and asked about program satisfaction, opportunities, and health behaviors. Michigan Vital Statistics records were used to ascertain controls (N = 12,030) and pregnancy and infant health outcomes. Logistic and linear regression were used to examine the association between WIN Network participation and pregnancy and infant health outcomes. The WIN Network participants were less likely than controls to be admitted to the neonatal intensive care unit (odds ratio = 0.55, 95% CI 0.33-0.93) and had a longer gestational length (mean difference = 0.42, 95% CI 0.02-0.81). Community health workers also shaped participants\u27 view of opportunities to thrive. This study demonstrates that community health workers can improve pregnancy outcomes for Black women

Composite Scalars at LEP: Constraining Technicolor Theories

LEPI and LEPII data can be used to constrain technicolor models with light, neutral pseudo-Nambu-Goldstone bosons, Pa. We use published limits on branching ratios and cross sections for final states with photons, large missing energy, jet pairs, and b bbar pairs to constrain the anomalous Pa Z0 Z0, Pa Z0 photon, and Pa photon photon couplings. From these results, we derive bounds on the size of the technicolor gauge group and the number of technifermion doublets in models such as Low-scale Technicolor.Comment: 27 pages (including title page), 15 figures, 6 tables. version 2: In addressing PRD referee comments, we have significantly expanded our manuscript, to include detailed discussion of limits from LEP II data, as well as expanding the number or specific models to which we apply our results. As a result, we have changed the title from "Z0 decays to composite scalars: constraining technicolor theories

The Involvement of NRF2 in Lung Cancer

Nuclear factor, erythroid-derived 2, like 2 (NRF2) is a key regulator of antioxidants and cellular stress responses. The role of NRF2 in pulmonary neoplasia, a diverse disease for which few biomarkers exist, is complicated and appears to depend on several main factors including the existence of activating mutations in NRF2 and/or loss of function mutations in KEAP1 and the stage of carcinogenesis studied, particularly in the mouse models tested. Therapeutic strategies for lung cancer targeting NRF2 have observed mixed results, both anti-and protumorigenic effects; however, these differences seem to reflect the mutation status of NRF2 or KEAP1. In this paper, we will discuss the studies on human NRF2 and the mechanisms proposed, several mouse models using various mice deficient in NRF2, as well as xenograft models, and the chemotherapeutic strategies using the NRF2 pathway

Red riding on hood: Exploring how galaxy colour depends on environment

Galaxy populations are known to exhibit a strong colour bimodality, corresponding to blue star-forming and red quiescent subpopulations. The relative abundance of the two populations has been found to vary with stellar mass and environment. In this paper, we explore the effect of environment considering different types of measurements. We choose a sample of $49, 911$ galaxies with $0.05 < z < 0.18$ from the Galaxy And Mass Assembly survey. We study the dependence of the fraction of red galaxies on different measures of the local environment as well as the large-scale "geometric" environment defined by density gradients in the surround- ing cosmic web. We find that the red galaxy fraction varies with the environment at fixed stellar mass. The red fraction depends more strongly on local environmental measures than on large-scale geometric environment measures. By comparing the different environmental densities, we show that no density measurement fully explains the observed environmental red fraction variation, suggesting the different measures of environmental density contain different information. We test whether the local environmental measures, when combined together, can explain all the observed environmental red fraction variation. The geometric environment has a small residual effect, and this effect is larger for voids than any other type of geometric environment. This could provide a test of the physics applied to cosmological-scale galaxy evolution simulations as it combines large-scale effects with local environmental impact.Comment: Accepted for publication in MNRAS; 16 pages; 10 figures; 2 tables

Access to interpreting services in England: secondary analysis of national data

Background: Overcoming language barriers to health care is a global challenge. There is great linguistic diversity in the major cities in the UK with more than 300 languages, excluding dialects, spoken by children in London alone. However, there is dearth of data on the number of non-English speakers for planning effective interpreting services. The aim was to estimate the number of people requiring language support amongst the minority ethnic communities in England. Methods: Secondary analysis of national representative sample of subjects recruited to the Health Surveys for England 1999 and 2004. Results: 298,432 individuals from the four main minority ethnic communities (Indian, Pakistani, Bangladeshi and Chinese) who may be unable to communicate effectively with a health professional. This represents 2,520,885 general practice consultations per year where interpreting services might be required. Conclusion: Effective interpreting services are required to improve access and health outcomes of non-English speakers and thereby facilitate a reduction in health inequalities

Children's understandings of obesity, a thematic analysis

Childhood obesity is a major concern in today’s society. Research suggests the inclusion of the views and understandings of a target group facilitates strategies that have better efficacy. The objective of this study was to explore the concepts and themes that make up children’s understandings of the causes and consequences of obesity. Participants were selected from Reception (4-5 years old) and Year 6 (10-11 years old), and attended a school in an area of Sunderland, in North East England. Participants were separated according to age and gender, resulting in four focus groups, run across two sessions. A thematic analysis (Braun & Clarke, 2006) identified overarching themes evident across all groups, suggesting the key concepts that contribute to children’s understandings of obesity are ‘‘Knowledge through Education,’’ ‘‘Role Models,’’ ‘‘Fat is Bad,’’ and ‘‘Mixed Messages.’’ The implications of these findings and considerations of the methodology are discussed in full

Freezing by Monte Carlo Phase-Switch

We describe a Monte Carlo procedure which allows sampling of the disjoint configuration spaces associated with crystalline and fluid phases, within a single simulation. The method utilises biased sampling techniques to enhance the probabilities of gateway states (in each phase) which are such that a global switch (to the other phase) can be implemented. Equilibrium freezing-point parameters can be determined directly; statistical uncertainties prescribed transparently; and finite-size effects quantified systematically. The method is potentially quite general; we apply it to the freezing of hard spheres.Comment: 5 pages, 2 figure

Cosmic Necklaces and Ultrahigh Energy Cosmic Rays

Cosmic necklaces are hybrid topological defects consisting of monopoles and strings, with two strings attached to each monopole. We argue that the cosmological evolution of necklaces may significantly differ from that of cosmic strings. The typical velocity of necklaces can be much smaller than the speed of light, and the characteristic scale of the network much smaller than the horizon. We estimate the flux of high-energy protons produced by monopole annihilation in the decaying closed loops. For some reasonable values of the parameters it is comparable to the observed flux of ultrahigh-energy cosmic rays.Comment: 10 pages, Revtex, 1 figur