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    Additional file 1: of GWAS-identified CCR1 and IL10 loci contribute to M1 macrophage-predominant inflammation in Behçet’s disease

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    Figure S1. Comparison of phenotypic features and cytokine profiles between M1 and M2 cultured cells. Figure S2. eQTL effect of rs7616215 on CCR2 and CCR1. Figure S3. Detailed results of chemotaxis of M2 Mφ toward various concentrations of MIP-1α. Figure S4. Differences in CCR1 positivity (fluorescence-activated cell sorting) between treatments. a Biologics. b Colchicine. c Prednisolone. Figure S5. The number of differentiated Mφ in vitro in HC and BD. Figure S6. eQTL effect of rs1518111 on IL-10 protein and mRNA. Figure S7. Schema showing our proposed immunological responses in BD. Table S1. Characteristics of patients with BD who participated in the study. Table S2. Characteristics of HC study participants. (DOCX 9663 kb
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