Early uptake and continuous accumulation of thallium-201 chloride in a benign mixed tumor of soft tissue: Case Report

A case of benign mixed tumor of the soft tissue in a 64-year-old Japanese male is presented. He noticed a painless, elastic hard mass sized 3 cm in the right knee, which gradually grew larger and harder in the last 5 years. Magnetic resonance imaging demonstrated a mass lesion embedded in the subcutaneous tissue with low and high signal intensity at T1- and T2-weighted images, respectively. Tl-201 scintigraphy showed an early uptake of Tl-201 within the lesion at 10 minutes after injection, which was slightly decreased but still continued at 2 hours later. The patient underwent a resection of tumor, and the pathological diagnosis was a benign mixed tumor of soft tissue without high vascularity, characterized by histological features similar to pleomorphic adenomas in the salivary glands. Immunohistochemical study proved expression of Na(+)/K(+)-ATPase of tumor cells. Overexpression of Na(+)/K(+)-ATPase of the tumor might be responsible for the early uptake of Tl-201, and poor vascular structure in this tumor might lead to continuous accumulation. The Tl-201 scintigraphic features of mixed tumor of soft tissue are assessed to resemble those of malignant soft tissue tumors

Metagenomic identification of pathogenic bacteria for pneumonia from postmortem lung tissue

Pathologists have been concerned about the validity of bacterial cultures from lung tissue for the postmortem identification of pneumonia-associated pathogens. Therefore, we studied whether pathogenic bacteria that cause pneumonia could be identified via the metagenomic analysis of lung tissue sampled at autopsy from 11 pneumonia cases and nine non-pneumonia cases. We demonstrated that metagenomic analysis of the postmortem lung microbiota could identify a bacterial genus as a pneumonia pathogen when the genus was predominant and an established pathogen. However, it is important to diagnose Enterobacteriaceae or anaerobic bacteria as pneumonia pathogens, because their abundance in the lung microbiota of non-pneumonia cases supports postmortem translocation and replacement. Moreover, we confirmed that postmortem bacterial culture from lung tissue could be misleading for the identification of the pneumonia pathogen based on postmortem anaerobic changes and artificial culture conditions. To our knowledge, this study is the first to demonstrate the conditions under which metagenomic analysis of postmortem lung tissue can identify bacterial genera that cause pneumonia

The relation of the easily decomposable organic matter of the paddy soil to its colloidal complexes

The previous references indicate that on incubating at 30\u27 C under waterlodged condition, the mineralization of organic nitrogen of the paddy soil hardly takes place in wet soil untreated, whereas markedly in soils respectively air-dried, added sufficient alkali to reach over pH 9, and added the neutral salts such as NaF, Na2HPO4, Na2C2O4 etc, which are soil humus eptizable. The incubation of wot soil untreated, however, leads to the mineralization of soil organic nitrogen by raising the incubating temperature from 30℃ to 40℃. In this paper, we called all the organic matter easily mineralized by treatments above mentioned \u22easily decomposable organic matter, and studied, in the first, on the relation of such organic matter to Tyulin\u27s so-called organomineral colloidal complexes of paddy soil?G1, and G2 groups?, and in the second on it\u27s forms. From the results obtained in the first experiment; it was concluded that (1) the organic nitrogen mineralized by air-drying paddy soil is largely originatedfrom G1, (2) that mineralized by raising the incubating temperature from 30℃ to 40℃, with the exception of the annual water-lodged paddy soil, is largely originated from G2, (3) that mineralized by treating the paddy soil with alkali and adding the neutral sals is respectively originated from both G1 and G2. It was, therefore, elucidated that \u22easily decomposable organic matter\u22 is held on Tyulin\u27s so-called G1 and G2 groups. Now, when we call the organic matt e r which is peptized by the Tyulin\u27s method \u22easily soluble humus\u22, \u22easily decomposable organic matter\u22 is presumably contained in it. The results obtained in the second lead to the conclusion that easily soluble humus is for the most part Simon\u27s so-called rotted products and Page\u27s so-called non-humic matter, and that \u22easily decomposable organic matter\u22 is a part of the rotted products and non-humic matter.水田土壌の有機態窒素の無機化促進法としては, 従来の研究から, 乾土効果, 地温上昇, 土壌の稀薄アルカリ処理数果, 腐植解膠性中性毒類添加の数果等が挙げられるが, 効果筆者等はこのような処理方法で微生物によつて無機化される有機態窒素を易分解性有機物と呼ぴ, 易分解性有機物とチュリンの所謂土壌有機・無機膠質複合体との関係, 易分解性有機物の腐植の形態等に就いて実験を行い, 次のような結論を得た. (1) 乾土数果, 即ち水田土壌を予じめ風乾して, これを湛水放置した場合に無機化する有機態窒素の大部分はチューリンの所謂G1膠質群中にある. (2) 地温上昇効果, 即ち水田土壌を濕潤土のまま湛水放置し, 放置温度を30℃から40℃に上げる場合に無機化する有機態窒素は勿論G2膠質群中にもあるが, その大部は, 濕田を除けば, チューリンの所謂G2膠質群中にある. (3) 稀薄アルカリ処理効果及び腐植解膠性中性塩類の添加数果, 即ち水田の濕潤土にアルカリを添加し約pH9に調節後, これを湛水放置した場合に無機化する有機態窒素及び腐植解膠性中性塩類を, 腐植の解膠を起す程度に添加し湛水放置した場合に無機化する有機態窒素はG1三及びG2膠質群に明かにまたがつていることが確められた. 何れにしても, 易分解性有機物にはチューリンの所謂G1, G2膠質群中にあることは確である. そして今土壌を稀薄なHCI(0.01N)で処理水洗した後, アルカリ性(0.01N)とした場合に分散して来る有機物を易溶性有機物と呼べぱ, 易努解性有機勃は易溶性有機物中に含有されている. 更に易分解性有機物は易溶性有機物の中,腐植化の進んでいないものであることが推定された