Physical Activity and Sedentary Behavior of Cancer Survivors and Non-Cancer Individuals: Results from a National Survey

Increasing physical activity and decreasing sedentary behavior are associated with a higher quality of life and lower mortality rates for cancer survivors, a growing population group. Studies detailing the behavior of cancer survivors are limited. Therefore, we investigated physical activity and sedentary behavior of cancer survivors using data from the National Health and Nutrition Examination Survey (NHANES) 2007–2010. Participants were those who provided physical activity and sedentary behavior data. Those who were pregnant,old, or10,472 non-cancer participants. After adjustment for age, race, gender, education status, body mass index, and smoking status, cancer survivors (n = 10,472) reported significantly longer duration of sedentary behavior (OR = 1.42, 95% CI (1.12, 1.80) for 8 or more hours, p-value for trend = 0.09), compared to non-cancer participants (n = 741). They also reported non-significant increases in maximum intensity, duration, frequency, and energy expenditure, whereas they reported significant increases in moderate intensity (OR = 1.26, 95% CI (1.01, 1.57)), moderate frequency (1–4 times/week) (OR = 1.32, 95% CI (1.00, 1.74)), and moderate energy expenditure (4018.5–7623.5 kcal) (OR = 1.30, 95% CI (1.00, 1.71)) of physical activity, compared to non-cancer participants. These patterns are similar for breast and prostate cancer survivors, with prostate cancer survivors more likely to engage in physical activity for more than one hour per day (OR = 1.98, 95% CI (1.05, 3.71)). Our findings suggest that cancer survivors tend to have more physical activity, but they are also more likely to engage in sedentary behavior

Global distribution of the sickle cell gene and geographical confirmation of the malaria hypothesis

It has been 100 years since the first report of sickle haemoglobin (HbS). More than 50 years ago, it was suggested that the gene responsible for this disorder could reach high frequencies because of resistance conferred against malaria by the heterozygous carrier state. This traditional example of balancing selection is known as the 'malaria hypothesis'. However, the geographical relationship between the transmission intensity of malaria and associated HbS burden has never been formally investigated on a global scale. Here, we use a comprehensive data assembly of HbS allele frequencies to generate the first evidence-based map of the worldwide distribution of the gene in a Bayesian geostatistical framework. We compare this map with the pre-intervention distribution of malaria endemicity, using a novel geostatistical area-mean comparison. We find geographical support for the malaria hypothesis globally; the relationship is relatively strong in Africa but cannot be resolved in the Americas or in Asia

Demographic and health-related characteristics of study participants by cancer status in the NHANES 2007–2008 and 2009–2010 cycles^*.

*<p>those with time since diagnosis <3 years excluded.</p>**<p>Other cancer includes lesser prevalent cancers or the specific cancer information was not available.</p

Association of Physical Activity and Sedentary Behaviors with Breast and Prostate Cancer in the NHANES 2007–2008 and 2009–2010 Cycles^*.

*<p>those with time since diagnosis <3 years excluded.</p>1<p>adjusted by age.</p>2<p>adjusted for age, race, education, Body Mass Index, smoking status.</p

sj-docx-1-eqs-10.1177_87552930231223995 – Supplemental material for The 2023 US National Seismic Hazard Model: Ground-motion characterization for the conterminous United States

Supplemental material, sj-docx-1-eqs-10.1177_87552930231223995 for The 2023 US National Seismic Hazard Model: Ground-motion characterization for the conterminous United States by Morgan P Moschetti, Brad T Aagaard, Sean K Ahdi, Jason Altekruse, Oliver S Boyd, Arthur D Frankel, Julie Herrick, Mark D Petersen, Peter M Powers, Sanaz Rezaeian, Allison M Shumway, James A Smith, William J Stephenson, Eric M Thompson and Kyle B Withers in Earthquake Spectra</p