11 research outputs found
Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1.
- Author
- Abdel-Aziz AK
- Abdelfatah S
- Abdellatif M
- Abdoli A
- Abel S
- Abeliovich H
- Abildgaard MH
- Abudu YP
- Acevedo-Arozena A
- Adamopoulos IE
- Adeli K
- Adolph TE
- Adornetto A
- Aflaki E
- Agam G
- Agarwal A
- Aggarwal BB
- Agnello M
- Agostinis P
- Agrewala JN
- Agrotis A
- Aguilar PV
- Ahmad ST
- Ahmed ZM
- Ahumada-Castro U
- Aits S
- Aizawa S
- Akkoc Y
- Akoumianaki T
- Akpinar HA
- Al-Abd AM
- Al-Akra L
- Al-Gharaibeh A
- Alaoui-Jamali MA
- Alberti S
- Alcocer-Gómez E
- Alessandri C
- Ali M
- Alim Al-Bari MA
- Aliwaini S
- Alizadeh J
- Almacellas E
- Almasan A
- Alonso A
- Alonso GD
- Altan-Bonnet N
- Altieri DC
- Alves da Costa C
- Alves S
- Alzaharna MM
- Amadio M
- Amantini C
- Amaral C
- Ambrosio S
- Amer AO
- Ammanathan V
- An Z
- Andersen SU
- Andrabi SA
- Andrade-Silva M
- Andres AM
- Angelini S
- Ann D
- Anozie UC
- Ansari MY
- Antas P
- Antebi A
- Antón Z
- Anwar T
- Apetoh L
- Apostolova N
- Araki T
- Araki Y
- Arasaki K
- Araya J
- Araújo WL
- Arden C
- Arguelles S
- Arias E
- Arikkath J
- Arimoto H
- Ariosa AR
- Armstrong-James D
- Arnauné-Pelloquin L
- Aroca A
- Arroyo DS
- Arsov I
- Artero R
- Arévalo M-A
- Asaro DML
- Aschner M
- Ashrafizadeh M
- Ashur-Fabian O
- Atanasov AG
- Au AK
- Auberger P
- Auner HW
- Aurelian L
- Autelli R
- Avagliano L
- Aveic S
- Aveleira CA
- Avin-Wittenberg T
- Aydin Y
- Ayton S
- Ayyadevara S
- Azzopardi M
- Baba M
- Backer JM
- Backues SK
- Bae D-H
- Bae O-N
- Bae SH
- Baehrecke EH
- Baek A
- Baek S-H
- Baek SH
- Bagetta G
- Bagniewska-Zadworna A
- Bai H
- Bai J
- Bai X
- Bai Y
- Bairagi N
- Baksi S
- Balazadeh S
- Balbi T
- Baldari CT
- Balduini W
- Ballabio A
- Ballester M
- Balzan R
- Bandopadhyay R
- Banerjee S
- Banerjee S
- Bao Y
- Baptista MS
- Baracca A
- Barbati C
- Bargiela A
- Barilà D
- Barlow PG
- Barmada SJ
- Barreiro E
- Barreto GE
- Bartek J
- Bartel B
- Bartolome A
- Barve GR
- Basagoudanavar SH
- Bassham DC
- Bast RC
- Basu A
- Batoko H
- Batten I
- Baulieu EE
- Baumgarner BL
- Bayry J
- Beale R
- Beau I
- Beaumatin F
- Bechara LRG
- Beck GR
- Beers MF
- Begun J
- Behl C
- Behrends C
- Behrens GMN
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- Bejarano E
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- Bellarosa C
- Belleudi F
- Bello-Morales R
- Belló Pérez M
- Beltran JSDO
- Beltran S
- Benbrook DM
- Bendorius M
- Benitez BA
- Benito-Cuesta I
- Bensalem J
- Berchtold MW
- Berezowska S
- Bergamaschi D
- Bergami M
- Bergmann A
- Berliocchi L
- Berlioz-Torrent C
- Bernard A
- Berthoux L
- Besirli CG
- Besteiro S
- Betin VM
- Beyaert R
- Bezbradica JS
- Bhaskar K
- Bhatia-Kissova I
- Bhattacharya R
- Bhattacharya S
- Bhattacharyya S
- Bhuiyan MS
- Bhutia SK
- Bi L
- Bi X
- Biden TJ
- Bijian K
- Billes VA
- Binart N
- Bincoletto C
- Birgisdottir AB
- Bjorkoy G
- Blanco G
- Blas-Garcia A
- Blasiak J
- Blomgran R
- Blomgren K
- Blum JS
- Boada-Romero E
- Boban M
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- Bonifacino JS
- Boone BA
- Bootman MD
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- Bornhauser BC
- Borthakur G
- Bosch J
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- Botas J
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- Boulton ME
- Bourdenx M
- Bourgeois B
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- Bousquet G
- Boya P
- Bozhkov PV
- Bozi LHM
- Bozkurt TO
- Brackney DE
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- Brandts CH
- Braun RJ
- Braus GH
- Bravo-Sagua R
- Bravo-San Pedro JM
- Brest P
- Bringer M-A
- Briones-Herrera A
- Broaddus VC
- Brodersen P
- Brodsky JL
- Brody SL
- Bronson PG
- Bronstein JM
- Brown CN
- Brown RE
- Brum PC
- Brumell JH
- Brunetti-Pierri N
- Bruno D
- Bryson-Richardson RJ
- Bucci C
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- Buchan JR
- Buchrieser C
- Buckingham EM
- Budak H
- Budini M
- Bueno M
- Buitrago-Molina LE
- Bultynck G
- Burada F
- Buraschi S
- Burgoyne JR
- Burón MI
- Bustos V
- Butturini E
- Byrd A
- Bánréti Á
- Büttner S
- Cabas I
- Cabrera-Benitez S
- Cadwell K
- Cai J
- Cai L
- Cai Q
- Cairó M
- Calbet JA
- Caldwell GA
- Caldwell KA
- Call JA
- Calvani R
- Calvo AC
- Calvo-Rubio Barrera M
- Camara NO
- Camonis JH
- Camougrand N
- Campanella M
- Campbell EM
- Campbell-Valois F-X
- Campello S
- Campesi I
- Campos JC
- Camuzard O
- Cancino J
- Candido de Almeida D
- Canesi L
- Caniggia I
- Canonico B
- Cantí C
- Cao B
- Caraglia M
- Caramés B
- Carchman EH
- Cardenal-Muñoz E
- Cardenas C
- Cardenas L
- Cardoso SM
- Carew JS
- Carle GF
- Carleton G
- Carloni S
- Carmona-Gutierrez D
- Carneiro LA
- Carnevali O
- Carosi JM
- Carra S
- Carrier A
- Carrier L
- Carroll B
- Carter AB
- Carvalho AN
- Casanova M
- Casas C
- Casas J
- Cassioli C
- Castillo EF
- Castillo K
- Castillo-Lluva S
- Castoldi F
- Castori M
- Castro AF
- Castro-Caldas M
- Castro-Hernandez J
- Castro-Obregon S
- Catz SD
- Cavadas C
- Cavaliere F
- Cavallini G
- Cavinato M
- Cayuela ML
- Cebollada Rica P
- Cecarini V
- Cecconi F
- Cechowska-Pasko M
- Cenci S
- Ceperuelo-Mallafré V
- Cerqueira JJ
- Cerutti JM
- Cervia D
- Cetintas VB
- Cetrullo S
- Chae H-J
- Chagin AS
- Chai C-Y
- Chakrabarti G
- Chakrabarti O
- Chakraborty T
- Chakraborty T
- Chami M
- Chamilos G
- Chan DW
- Chan ED
- Chan EYW
- Chan H
- Chan HH
- Chan HYE
- Chan MTV
- Chan YS
- Chandra PK
- Chang C
- Chang C-P
- Chang H-C
- Chang K
- Chao J
- Chapman T
- Charlet-Berguerand N
- Chatterjee S
- Chaube SK
- Chaudhary A
- Chauhan S
- Chaum E
- Checler F
- Cheetham ME
- Chen C-S
- Chen G-C
- Chen J-F
- Chen L
- Chen L
- Chen LL
- Chen M
- Chen M-K
- Chen N
- Chen Q
- Chen R-H
- Chen S
- Chen W
- Chen W
- Chen X
- Chen X-M
- Chen X-W
- Chen Y
- Chen Y
- Chen Y
- Chen Y-G
- Chen Y-J
- Chen Y-Q
- Chen Z
- Chen Z
- Chen Z
- Chen Z-H
- Chen ZJ
- Chen ZS
- Cheng H
- Cheng J
- Cheng S-Y
- Cheng W
- Cheng X
- Cheng X-T
- Cheng Y
- Cheng Z
- Cheong H
- Cheong JK
- Chernyak BV
- Cherry S
- Cheung CFR
- Cheung CHA
- Cheung K-H
- Chevet E
- Chi RJ
- Chiang AKS
- Chiaradonna F
- Chiarelli R
- Chiariello M
- Chica N
- Chiocca S
- Chiong M
- Chiou S-H
- Chiramel AI
- Chiurchiù V
- Cho D-H
- Choe S-K
- Choi AMK
- Choi ME
- Choudhury KR
- Chow NS
- Chu CT
- Chua JJE
- Chua JP
- Chung H
- Chung KP
- Chung S
- Chung S-H
- Chung Y-L
- Cianfanelli V
- Ciechomska IA
- Cifuentes M
- Cinque L
- Cirak S
- Cirone M
- Clague MJ
- Clarke R
- Clementi E
- Coccia EM
- Codogno P
- Cohen E
- Cohen MM
- Colasanti T
- Colasuonno F
- Colbert RA
- Colell A
- Coll NS
- Collins MO
- Colombo MI
- Colón-Ramos DA
- Combaret L
- Comincini S
- Cominetti MR
- Consiglio A
- Conte A
- Conti F
- Contu VR
- Cookson MR
- Coombs KM
- Coppens I
- Corasaniti MT
- Cordes N
- Corkery DP
- Cortese K
- Costa MDC
- Costantino S
- Costelli P
- Coto-Montes A
- Crack PJ
- Crespo JL
- Criollo A
- Crippa V
- Cristofani R
- Csizmadia T
- Cuadrado A
- Cui B
- Cui J
- Cui Y
- Cui Y
- Culetto E
- Cumino AC
- Cybulsky AV
- Czaja MJ
- Czuczwar SJ
- D'Adamo S
- D'Amelio M
- D'Arcangelo D
- D'Lugos AC
- D'Orazi G
- da Silva JA
- Dafsari HS
- Dagda RK
- Dagdas Y
- Daglia M
- Dai X
- Dai Y
- Dai Y
- Dal Col J
- Dalhaimer P
- Dalla Valle L
- Dallenga T
- Dalmasso G
- Damme M
- Dando I
- Dantuma NP
- Darling AL
- Das H
- Dasarathy S
- Dasari SK
- Dash S
- Daumke O
- Dauphinee AN
- Davies JS
- Davis RJ
- Davis T
- Dayalan Naidu S
- De Amicis F
- De Bosscher K
- De Felice F
- De Franceschi L
- De Leonibus C
- de Mattos Barbosa MG
- De Meyer GRY
- De Milito A
- De Nunzio C
- De Palma C
- De Santi M
- De Virgilio C
- De Zio D
- Debnath J
- DeBosch BJ
- Decuypere J-P
- Deehan MA
- Deflorian G
- DeGregori J
- Dehay B
- Del Rio G
- Delaney JR
- Delbridge LMD
- Delorme-Axford E
- Delpino MV
- Demarchi F
- Dembitz V
- Demers ND
- Deng H
- Deng Z
- Dengjel J
- Dent P
- Denton D
- DePamphilis ML
- Der CJ
- Deretic V
- Descoteaux A
- Devis L
- Devkota S
- Devuyst O
- Dewson G
- Dharmasivam M
- Dhiman R
- di Bernardo D
- Di Cristina M
- Di Domenico F
- Di Fazio P
- Di Fonzo A
- Di Guardo G
- Di Guglielmo GM
- Di Leo L
- Di Malta C
- Di Nardo A
- Di Rienzo M
- Di Sano F
- Diallinas G
- Diao J
- Diaz-Araya G
- Dickinson JM
- Diederich M
- Dieudé M
- Dikic I
- Ding S
- Ding W-X
- Dini L
- Dinic M
- Dinić J
- Dinkova-Kostova AT
- Dionne MS
- Distler JHW
- Diwan A
- Dixon IMC
- Djavaheri-Mergny M
- Dobrinski I
- Dobrovinskaya O
- Dobrowolski R
- Dobson RCJ
- Dokmeci Emre S
- Donadelli M
- Dong B
- Dong X
- Dong XC
- Dong Z
- Dorn Ii GW
- Dotsch V
- Dou H
- Dou J
- Dowaidar M
- Dridi S
- Drucker L
- du Toit A
- Du A
- Du C
- Du G
- Du H-N
- Du L-L
- Duan S-B
- Duan X
- Duarte SP
- Dubrovska A
- Dunlop EA
- Dupont N
- Durán RV
- Dwarakanath BS
- Dyshlovoy SA
- Dávila VA
- Díaz-Laviada I
- Ebrahimi-Fakhari D
- Eckhart L
- Edelstein CL
- Efferth T
- Eftekharpour E
- Eichinger L
- Eid N
- Eisenberg T
- Eissa NT
- Eissa S
- Ejarque M
- El Andaloussi A
- El-Hage N
- El-Naggar S
- El-Shafey ES
- Eleuteri AM
- Elgendy M
- Eliopoulos AG
- Elizalde MM
- Elks PM
- Elsasser H-P
- Elsherbiny ES
- Emerling BM
- Emre NCT
- Eng CH
- Engedal N
- Engelbrecht A-M
- Engelsen AST
- Enserink JM
- Escalante R
- Esclatine A
- Escobar-Henriques M
- Eskelinen E-L
- Espert L
- Eusebio M-O
- Fabrias G
- Fabrizi C
- Facchiano A
- Facchiano F
- Fadeel B
- Fader C
- Faesen AC
- Fairlie WD
- Falcó A
- Falkenburger BH
- Fan D
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- Fang EF
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- Farfel-Becker T
- Faure M
- Fazeli G
- Fedele AO
- Feldman AM
- Feng D
- Feng J
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- Ferguson TA
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- Fernie AR
- Fernández ÁF
- Fernández-Veledo S
- Ferrante AW
- Ferraresi A
- Ferrari MF
- Ferreira JCB
- Ferro-Novick S
- Figueras A
- Filadi R
- Filigheddu N
- Filippi-Chiela E
- Filomeni G
- Fimia GM
- Fineschi V
- Finetti F
- Finkbeiner S
- Fisher EA
- Fisher PB
- Flamigni F
- Fliesler SJ
- Flo TH
- Florance I
- Florey O
- Florio T
- Fodor E
- Follo C
- Fon EA
- Forlino A
- Fornai F
- Fortini P
- Fracassi A
- Fraldi A
- Franco B
- Franco R
- Franconi F
- Frankel LB
- Friedman SL
- Fröhlich LF
- Frühbeck G
- Fuentes JM
- Fujiki Y
- Fujita N
- Fujiwara Y
- Fukuda M
- Fulda S
- Furic L
- Furuya N
- Fusco C
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- Galasso A
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- Garg AD
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- Gentle IE
- Gerbino V
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- Goldstone DC
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- Hooper LV
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- Hubner CA
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- Hyung-Ryong Kim
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- Jimenez-Sanchez M
- Jin E-J
- Jin F
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- Jo E-K
- Joffre C
- Johansen T
- Johnson GVW
- Johnston SA
- Jokitalo E
- Jolly MK
- Joosten LAB
- Jordan J
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- Ju D
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- Judith D
- Juhász G
- Jun Y
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- Kaludercic N
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- Kaminskyy VO
- Kanamori H
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- Kanthasamy A
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- Kapuy O
- Karamouzis MV
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- Kaufmann SHE
- Kauppinen A
- Kaushal GP
- Kaushik S
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- Keating DJ
- Keber U
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- Keller CW
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- Kenchappa CS
- Kenific CM
- Kepp O
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- Kern A
- Ketteler R
- Keulers TG
- Khalfin B
- Khalil H
- Khambu B
- Khan SY
- Khandelwal VKM
- Khandia R
- Kho W
- Khobrekar NV
- Khuansuwan S
- Khundadze M
- Killackey SA
- Kim D
- Kim D-E
- Kim D-H
- Kim DR
- Kim E-K
- Kim EY
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- Warnes G
- Warnsmann V
- Watada H
- Watanabe E
- Watchon M
- Wawrzyńska A
- Weaver TE
- Wegrzyn G
- Wehman AM
- Wei H
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- Wei Y
- Weiergräber OH
- Weihl CC
- Weindl G
- Weiskirchen R
- Wells A
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- Wheatley SP
- Whitton JL
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- Wildenberg ME
- Wileman T
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- Xu WW
- Xu X
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- Yakhine-Diop SMS
- Yamaguchi M
- Yamaguchi O
- Yamamoto A
- Yamashina S
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- Yao H
- Yao S
- Yao X
- Yao Y-G
- Yao Y-M
- Yasui T
- Yazdankhah M
- Yen PM
- Yi C
- Yi-Ren Hong C-WH
- Yin X-M
- Yin Y
- Yin Z
- Yin Z
- Ying M
- Ying Z
- Yip CK
- Yiu SPT
- Yoo YH
- Yoshida K
- Yoshii SR
- Yoshimori T
- Yousefi B
- Yu B
- Yu H
- Yu J
- Yu J
- Yu L
- Yu M-L
- Yu S-W
- Yu VC
- Yu WH
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- Yu Z
- Yuan J
- Yuan L-Q
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- Yuan S-SF
- Yuan Y
- Yuan Z
- Yue J
- Yue Z
- Yun J
- Yung RL
- Zacks DN
- Zaffagnini G
- Zambelli VO
- Zanella I
- Zang QS
- Zanivan S
- Zappavigna S
- Zaragoza P
- Zarbalis KS
- Zarebkohan A
- Zarrouk A
- Zeitlin SO
- Zeng J
- Zeng J-D
- Zhan L
- Zhang B
- Zhang DD
- Zhang H
- Zhang H
- Zhang H
- Zhang H
- Zhang H
- Zhang H
- Zhang H
- Zhang H-L
- Zhang J
- Zhang J
- Zhang J-P
- Zhang KYB
- Zhang L
- Zhang L
- Zhang L
- Zhang L
- Zhang LW
- Zhang M
- Zhang P
- Zhang S
- Zhang W
- Zhang X
- Zhang X
- Zhang X
- Zhang X
- Zhang X
- Zhang X-W
- Zhang XD
- Zhang Y
- Zhang Y
- Zhang Y
- Zhang Y
- Zhang Y
- Zhang Y-D
- Zhang Y-Y
- Zhang Z
- Zhang Z
- Zhang Z
- Zhang Z
- Zhang Z
- Zhang Z
- Zhao H
- Zhao L
- Zhao S
- Zhao T
- Zhao X-F
- Zhao Y
- Zhao Y
- Zhao Y
- Zhao Y
- Zheng G
- Zheng K
- Zheng L
- Zheng S
- Zheng X-L
- Zheng Y
- Zheng Z-G
- Zhivotovsky B
- Zhong Q
- Zhou A
- Zhou B
- Zhou C
- Zhou G
- Zhou H
- Zhou H
- Zhou H
- Zhou J
- Zhou J
- Zhou J
- Zhou J
- Zhou K
- Zhou R
- Zhou X-J
- Zhou Y
- Zhou Y
- Zhou Y
- Zhou Z
- Zhou Z-Y
- Zhu B
- Zhu C
- Zhu G-Q
- Zhu H
- Zhu H
- Zhu H
- Zhu W-G
- Zhu Y
- Zhu Y
- Zhuang H
- Zhuang X
- Zientara-Rytter K
- Zimmermann CM
- Ziviani E
- Zoladek T
- Zong W-X
- Zorov DB
- Zorzano A
- Zou W
- Zou Z
- Zou Z
- Zuryn S
- Zwerschke W
- Álvarez ÉMC
- Ávalos Y
- Önal G
- Üstün S
- Čolić M
- Đokić J
- Žerovnik E
- Publication venue
- 'Informa UK Limited'
- Publication date
- 01/01/2021
- Field of study
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field
Low incidence of inbreeding in a long-lived primate population isolated for 75 years
- Author
- A Widdig
- A Widdig
- A Widdig
- A Widdig
- A Widdig
- ADJ Overall
- AE Pusey
- AF Dixson
- Angelina Ruiz-Lambides
- Anja Widdig
- B Goossens
- BFJ Manly
- BM Marriott
- C Dubuc
- C Dubuc
- CA Walling
- CE Grueber
- CL Hoffman
- CM Costello
- CR Carpenter
- CR Carpenter
- CR Duggleby
- D Bates
- D Pfefferle
- D Pfefferle
- DC Adams
- DG Lindburg
- DJ Barr
- DJ Melnick
- DL Cheney
- DR Bilski
- DW Coltman
- DY Li
- E Rioux-Paquette
- E Rioux-Paquette
- EA Archie
- F Balloux
- F Levréro
- G Campbell
- G Ólafsdóttir
- GE Blomquist
- H Baayen
- H Schielzeth
- HR Taylor
- J Cassinello
- J Colvin
- J Huisman
- J Kuester
- J Manson
- J Pemberton
- J Prado-Martinez
- J Satkoski
- J Slate
- J Slate
- J Slate
- J Wang
- JD Berard
- JD Berard
- JE Powell
- JF Nielsen
- JH Manson
- JI Hoffman
- JL Zehr
- JM Aparicio
- JM Pemberton
- JM Rijks
- JS Alho
- K Acevedo-Whitehouse
- K Bean
- K Ralls
- K Rzewuska
- L Muniz
- Lars Kulik
- Laura Muniz
- LF Keller
- LF Keller
- LF Keller
- M Charpentier
- M Charpentier
- M Charpentier
- M Dorostkar
- M Kardos
- M Szulkin
- M Szulkin
- Mirjam Minkner
- MJ Ruiz-López
- O Liberg
- Olaf Junge
- PK Seth
- PW Hedrick
- R Core Team
- R Development Core Team
- R Fredrickson
- R Hernández-Pacheco
- Roger Mundry
- S Bensch
- S Edmands
- S Gouzoules
- S Kanthaswamy
- S Nakagawa
- SA Altmann
- SC Alberts
- SC Alberts
- SH Kim
- SS Taylor
- ST Kalinowski
- Stefanie Bley
- TC Marshall
- TC Marshall
- TH Clutton-Brock
- U Knief
- W Amos
- W Forstmeier
- Y Sugiyama
- Y Takahata
- Yvonne Barth
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Photoprotection of Buddleja cordata extract against UVB-induced skin damage in SKH-1 hairless mice
- Author
- A Alonso-Castro
- A Petrova
- Adriana Montserrat Espinosa González
- Ana María García Bores
- B Halliwell
- D Elder
- D Mitchell
- Diana Matamoros De Maria y Campos
- E Maverakis
- F Afaq
- F Lohézic-Le Dévéhat
- F Menaa
- G Mandalari
- HD Scheibmeir
- J Lademann
- J Rzedowski
- JD Mahlke
- JG Avila
- JG Avila Acevedo
- Jorge Campos Contreras
- José del Carmen Benitez Flores
- José Guillermo Avila Acevedo
- José Luis Muñoz López
- L Acevedo
- L Lesur
- M De La Cruz
- M Martínez
- M Martínez-Vázquez
- M Martínez-Vázquez
- O Trujillo
- P Hockberger
- P Thitilertdecha
- PJ Houghton
- R Bye
- S González
- S Ramachandran
- SA Wissing
- Saul Flores Maya
- T Ma
- Tzasna Hernández Delgado
- Y Frum
- Y Matsumura
- Y Pan
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Modified penicillin acylase signal peptide allows the periplasmic production of soluble human interferon-γ but not of soluble human interleukin-2 by the Tat pathway in Escherichia coli
- Author
- A Kimmenade van
- A Sturm
- A. De León-Rodríguez
- A. P. Barba-De la Rosa
- AP Hinsley
- BC Berks
- C Robinson
- D Koshland
- E. Medina-Rivero
- EG Bogsch
- J Pratap
- J Robbens
- JD Thomas
- JM Betton
- JY Kim
- L. G. Ordoñez-Acevedo
- L. M. T. Paz-Maldonado
- O Monroy-Lagos
- P Denèfle
- R Xu
- SC Makrides
- T Palmer
- TL Yahr
- V. E. Balderas-Hernández
- VP Hytonen
- Z Ignatova
- Z Ignatova
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
In vivo
- Author
- Amaya-Guerra C
- Amaya-Guerra CA
- Chavez A
- Chuck-Hernández C
- Erdman JW
- Figueroa-Cárdenas JD
- Giampietro PG
- Gonzalez-Agramon M
- Karr-Lilienthal LK
- Kurpad AV
- Laura Acevedo-Pacheco
- Lazo-Vélez MA
- Mahmoodi MR
- Messina MJ
- Nishinari K
- Okezie B
- Pasini G
- Pereira Lobato LP
- Perez-Carrillo E
- Pope LL
- Ribotta PD
- Schaafsma G
- Sergio O. Serna-Saldívar
- Serna-Saldivar SO
- Serna-Saldivar SO
- Serna-Saldívar SO
- Serrem CA
- Stylianopoulos C
- Tham DM
- Van den Briel T
- Wouters AG
- Yamada EA
- Publication venue
- 'Co-Action Publishing'
- Publication date
- Field of study
Invasion ecology of wild pigs (Sus scrofa) in Florida, USA: the role of humans in the expansion and colonization of an invasive wild ungulate
- Author
- A Bonin
- A Kidd
- A Mousadik El
- A Robic
- AJ Carpio
- Antoinette J. Piaggio
- B Bankovich
- B Gruber
- B Smith
- Brandon M. Parker
- BS Weir
- C Poteaux
- C Vernesi
- CE Holleley
- Cortney L. Pylant
- CR Dickman
- D Choquenot
- D Falush
- DA Earl
- DA Wardle
- E Paradis
- E Randi
- EM Cárdenas-Canales
- Felipe A. Hernández
- FS Chapin
- G Evanno
- G Kaminski
- G Wood
- GA Rohrer
- GA Wilson
- GH Matschke
- H Ellegren
- IS Nikolov
- J Corander
- J Corander
- J Goudet
- J Hone
- J Lopez
- J Pritchard
- J Zivin
- JA Crooks
- James D. Austin
- JD Waithman
- JJ Mayer
- JN Caudell
- JO Hampton
- KP Burnham
- KT Gioeli
- L Yiming
- LJ Alexander
- M Scandura
- MA Tabak
- Michael P. Milleson
- MN Barrios-Garcia
- NW Seward
- OE Sala
- P Acevedo
- P Cassey
- P Genovesi
- P Pysek
- PBS Spencer
- PE Hulme
- R Peakall
- RC Belden
- RC Lonsinger
- S Dray
- S Holm
- S Wright
- S Wright
- Samantha M. Wisely
- SJ Puechmaille
- SN Bevins
- SP Bratton
- Stacey L. Lance
- T Jombart
- T Jombart
- Timothy J. Smyser
- TM Gabor
- WR Rice
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Co-circulation and simultaneous co-infection of dengue, chikungunya, and zika viruses in patients with febrile syndrome at the Colombian-Venezuelan border
- Author
- A Arias
- A Roth
- A Wilder-Smith
- A Yamanaka
- AB Kawiecki
- AC Morrison
- AG L'Huillier
- AJ Rodríguez-morales
- AP Alarcon-Cruz
- BP Drumond
- C Gomez-Calderon
- CF Estofolete
- CN Soares
- D Musso
- D Musso
- DJ Gubler
- E Arroyave
- F Diaz-Quijano
- FR Rodríguez-Villamarín
- G Gutierrez
- G Valentine
- HS Chahar
- IA Rodenhuis-Zybert
- J Mlakar
- JA Cardona-Ospina
- JA Diaz-Quinonez
- JD Rodas
- JJ Waggoner
- JJ Waggoner
- JJ Waggoner
- JL San Martin
- JS Salas-Benito
- Julian Ruiz-Saenz
- K Laiton-Donato
- L Furuya-Kanamori
- L Priyamvada
- L Romero-Vega
- LA Villar
- LJ Chien
- Lucy Jaimes Villamizar
- M Carabali
- M Martinez-Gutierrez
- M Pfeffer
- Marlen Martínez-Gutierrez
- Marlen Yelitza Carrillo-Hernández
- MG Teixeira
- MHS Paiva
- MK Soumahoro
- N Acevedo
- N Alvis-Guzman
- N Yuki
- O Faye
- P Singh
- R Adiga
- R Omarjee
- R Pessôa
- RE Ocazionez
- RE Ocazionez-Jiménez
- RS Lanciotti
- S Gómez
- S Mattar
- S Mattar
- S Naccache
- SC Weaver
- SC Weaver
- Sergio Yebrail Gómez-Rangel
- SI Sardi
- T Saswat
- V Gomez Arcila
- VG Ramachandran
- VM Cao-Lormeau
- W Dejnirattisai
- W Villamil-Gomez
- WE Villamil-Gomez
- WE Villamil-Gomez
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Cocaine Sensitization Increases I h Current Channel Subunit 2 (HCN2) Protein Expression in Structures of the Mesocorticolimbic System
- Author
- A Arroyo
- A Lorincz
- A Ludwig
- AC Calvo
- AL Tarentino
- AM Barth
- AM Wells
- AP Hegle
- B Much
- B Santoro
- Bermary Santos-Vera
- BJ Wainger
- BP Bean
- BT Chen
- C Chauvet
- C Luscher
- C Ulens
- C Ulens
- C Zabel
- Carlos A. Jiménez-Rivera
- D DiFrancesco
- DB Carr
- DB Carr
- DW Self
- DW Self
- EB Margolis
- EB Margolis
- EC Emery
- F Arencibia-Albite
- Francisco Arencibia-Albite
- FW Hopf
- H Neuhoff
- H Tu
- H Wei-qing
- Hermes G. García Marrero
- HJ Groenewegen
- HW Shen
- HY Chu
- I Papp
- J Dyhrfjeld-Johnsen
- J Kim
- J Kusch
- J McDaid
- JA Kauer
- JA Kauer
- JA Lamas
- JC Chen
- JC Magee
- JD Steketee
- Jorge D. Miranda
- Juan M. Ramos Acevedo
- K Kim
- K Takasu
- KC Schmitt
- KD Fischer-Smith
- L Matt
- LM Monteggia
- M Berrera
- M Day
- M Filip
- M Funahashi
- M Gao
- M Genlain
- M Ishikawa
- M Karreman
- M Leyton
- M Mameli
- M Migliore
- M Sofuoglu
- M Stramiello
- M Wang
- María E. Vélez-Hernández
- ME Reith
- ME Wolf
- MF Nolan
- MF Nolan
- MF Perez
- MJ Beckstead
- MJ Thomas
- MM Torregrossa
- MS Brodie
- MT Taber
- MU Inyushin
- N Uchimura
- NB Mercuri
- ND Volkow
- O Franz
- P Belujon
- P Mu
- PW Kalivas
- Q Zha
- R Surges
- RA Bender
- Rafael Vázquez-Torres
- S Kourrich
- S Xia
- SE Hyman
- SL Ingram
- SR Williams
- T Notomi
- T Okamoto
- TE Robinson
- TE Robinson
- TN Doan
- V Beaumont
- V Chevaleyre
- V Seutin
- Y Noam
- ZB You
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Effect of the COVID-19 pandemic on surgery for indeterminate thyroid nodules (THYCOVID): a retrospective, international, multicentre, cross-sectional study
- Author
- Abdallah A
- Abentroth AL
- Acheimastos V
- Agunaoun M
- Al Bisher HM
- Al Ghuzlan A
- Al-Suhaimi Ebtesam Abdullah
- Alakus H
- Alkan M
- Almaraz Almaraz MC
- Altmeier Julia
- Amram K
- Anajar Said
- Anesidis S
- Anestiadou E
- Angelucci D
- Ansaldo GL
- Antonopoulou MI
- Arciniegas M
- Arikan Akif Enes
- Armellin C
- Arredondo Saldaña G
- Astl J
- Athanasakis E
- Avenia S
- Aydın H
- Azaryan Irina
- Baba B
- Babala J
- Bains Lovenish
- Banús MV
- Barba-Valadez LA
- Barcons SV
- Basili Giancarlo
- Battafarano F
- Bayat A
- Bella RMC
- Benariba F
- Bernardi S
- Bignami EG
- Bitenc M
- Bitsianis S
- Bolaños de la Torre JDD
- Bolukbasi Hakan
- Bonati E
- Bonetti T
- Bononi Marco
- Borges FA
- Borumandi Farzad
- Bouchagier K
- Boudina M
- Bourial A
- Bozan Mehmet Buğra
- Brenta Gabriela
- Breuskin I
- Brock P
- Brunaud Laurent
- Brunner Maximilian
- Bruns C
- Buemi Antoine
- Burlacu MC
- Burton T
- Buta M
- Buzanakov D
- Caliseo C
- Callanan D
- Calu V
- Calò Pietro Giorgio
- Cameselle-Teijeiro JM
- Camilo-Junior DJ
- Canberk S
- Candalise V
- Candanedo-Gonzalez F
- Canu Gian Luigi
- Cappellacci Federico
- Carrillo Lizarazo LJ
- Cartwright Sara Burchfield
- Carvalho GB
- Casallas D
- Casolino C
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- Vargas-Osorio Kelly
- Vartanian JG
- Velázquez-Fernández David
- Verras GI
- Vithana Sanura Malinda Pallegoda
- Vithanage A
- Vázquez Rentería Rafael Sebastián
- Wijayalathge H
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- Wongwattana P
- Xavier-Junior Jose Candido
- Xenaki S
- Xie S
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- Yadav Sanjay Kumar
- Yang W
- Yilmaz S
- Yılmaz YF
- Yotsov T
- Yulian Erwin Danil
- Yücel Levent
- Zahid MT
- Zahradnikova Petra
- Zarogoulidis Paul
- Ziablitskaia Evgeniia
- Zielke A
- Zolotoukho Anna
- Čukman M
- Publication venue
- Publication date
- 01/01/2023
- Field of study
Background: Since its outbreak in early 2020, the COVID-19 pandemic has diverted resources from non-urgent and elective procedures, leading to diagnosis and treatment delays, with an increased number of neoplasms at advanced stages worldwide. The aims of this study were to quantify the reduction in surgical activity for indeterminate thyroid nodules during the COVID-19 pandemic; and to evaluate whether delays in surgery led to an increased occurrence of aggressive tumours.
Methods: In this retrospective, international, cross-sectional study, centres were invited to participate in June 22, 2022; each centre joining the study was asked to provide data from medical records on all surgical thyroidectomies consecutively performed from Jan 1, 2019, to Dec 31, 2021. Patients with indeterminate thyroid nodules were divided into three groups according to when they underwent surgery: from Jan 1, 2019, to Feb 29, 2020 (global prepandemic phase), from March 1, 2020, to May 31, 2021 (pandemic escalation phase), and from June 1 to Dec 31, 2021 (pandemic decrease phase). The main outcomes were, for each phase, the number of surgeries for indeterminate thyroid nodules, and in patients with a postoperative diagnosis of thyroid cancers, the occurrence of tumours larger than 10 mm, extrathyroidal extension, lymph node metastases, vascular invasion, distant metastases, and tumours at high risk of structural disease recurrence. Univariate analysis was used to compare the probability of aggressive thyroid features between the first and third study phases. The study was registered on ClinicalTrials.gov, NCT05178186.
Findings: Data from 157 centres (n=49 countries) on 87 467 patients who underwent surgery for benign and malignant thyroid disease were collected, of whom 22 974 patients (18 052 [78·6%] female patients and 4922 [21·4%] male patients) received surgery for indeterminate thyroid nodules. We observed a significant reduction in surgery for indeterminate thyroid nodules during the pandemic escalation phase (median monthly surgeries per centre, 1·4 [IQR 0·6-3·4]) compared with the prepandemic phase (2·0 [0·9-3·7]; p<0·0001) and pandemic decrease phase (2·3 [1·0-5·0]; p<0·0001). Compared with the prepandemic phase, in the pandemic decrease phase we observed an increased occurrence of thyroid tumours larger than 10 mm (2554 [69·0%] of 3704 vs 1515 [71·5%] of 2119; OR 1·1 [95% CI 1·0-1·3]; p=0·042), lymph node metastases (343 [9·3%] vs 264 [12·5%]; OR 1·4 [1·2-1·7]; p=0·0001), and tumours at high risk of structural disease recurrence (203 [5·7%] of 3584 vs 155 [7·7%] of 2006; OR 1·4 [1·1-1·7]; p=0·0039).
Interpretation: Our study suggests that the reduction in surgical activity for indeterminate thyroid nodules during the COVID-19 pandemic period could have led to an increased occurrence of aggressive thyroid tumours. However, other compelling hypotheses, including increased selection of patients with aggressive malignancies during this period, should be considered. We suggest that surgery for indeterminate thyroid nodules should no longer be postponed even in future instances of pandemic escalation.
Funding: None
Purinergic signalling in the urinary tract in health and disease
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- A Ahluwalia
- A Albino-Teixeira
- A Apostolidis
- A Apostolidis
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- A Athanasopoulos
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- A Garcia-Pascual
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- A Labadia
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- S Säve
- S Toji
- S Usune
- S Vaidyanathan
- S Valera
- S Valera
- S Wachter De
- S Yamada
- S Zhang
- S-H Liu
- SA Lewis
- SA Waterman
- SA Zderic
- SC Harrison
- SC Harrison
- SC Parija
- SD Chung
- SE Dahlén
- SE Holt
- SH Kang
- SH Liu
- SH Snyder
- SJ Borvendeg
- SJ Owen
- SJ Yang
- SL Stanton
- SM Callahan
- SM Marchenko
- SM Olsen
- SMO Hourani
- SMO Hourani
- SMO Hourani
- SO Suadicani
- SP Kelley
- SS Hegde
- ST Hu
- SX Zhang
- T Akasu
- T Gevaert
- T Hisayama
- T Imamura
- T Katsuragi
- T Katsuragi
- T Kitta
- T Kitta
- T Mochizuki
- T Nishimura
- T Nishimura
- T Tammela
- T Tammela
- T Utkan
- T Yokota
- TD Westfall
- TJ Heppner
- TJ Searl
- TK Kaan
- TL Tammela
- UJ Salmon
- V Cristofaro
- V Cristofaro
- V Kumar
- V Kumar
- V Kumar
- V Kumar
- V Ralevic
- V Werkström
- V Werkström
- VE Henderson
- VP Zagorodnyuk
- W Jänig
- W Rong
- W Rong
- W Sy De
- W Yu
- W Yu
- W Yu
- W Yu
- WC Chua
- WC Groat de
- WC Groat de
- WC Groat de
- WC Groat de
- WC Groat de
- WC Groat de
- WC Groat de
- WC Groat de
- WC Groat de
- WC Groat de
- WC Groat de
- WC Groat de
- WC Groat de
- WC Groat de
- WC Lee
- WD Cowan
- WD Steers
- WE Bradley
- WF McDonald
- WG Dail
- WS Ammons
- X Bo
- X Bo
- X Bo
- X Bo
- X Bo
- X Bo
- X Bo
- X Chen
- Y Cheng
- Y Cheng
- Y Cheng
- Y Cheng
- Y Cheng
- Y Igawa
- Y Igawa
- Y Igawa
- Y Ikeda
- Y Ito
- Y Kubota
- Y Li
- Y Semerdzhiev
- Y Sun
- Y Sun
- Y Sun
- Y Sun
- Y Sun
- Y Sun
- Y Wada
- Y Wang
- Y Yiangou
- Y Yu
- Y Yu
- Y Zhao
- Y Zhong
- Y Zhong
- Y Zhong
- Y-C Park
- Y-C Tong
- YC Tong
- YC Tong
- Z Wang
- Á Jenes
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study