5 research outputs found
Phenotypic Dissection of Bone Mineral Density Reveals Skeletal Site Specificity and Facilitates the Identification of Novel Loci in the Genetic Regulation of Bone Mass Attainment
- Author
- Ackert-Bicknell C.L. (Cheryl)
- Choi K. (Kunho)
- Davey-Smith G. (George)
- Econs M.J. (Michael)
- Eerden B.C.J. (Bram) van der
- Estrada Gil K. (Karol)
- Evans D.M. (David)
- Foroud T. (Tatiana)
- Gautvik K.M. (Kaare)
- Ge B. (Bing)
- Grundberg E. (Elin)
- Heppe D.H.M. (Denise)
- Hibbs M.A. (Matthew)
- Hofman A. (Albert)
- Jaddoe V.W.V. (Vincent)
- Kemp J.P. (John)
- Koller D.L. (Daniel)
- Kruithof C.J. (Claudia)
- Medina-Gomez M.C. (Carolina)
- Oei L. (Ling)
- Ohlsson C. (Claes)
- Peppel J. (Jeroen) van de
- Reppe S. (Sjur)
- Ring S.M. (Susan)
- Rivadeneira Ramirez F. (Fernando)
- St Pourcain B. (Beate)
- Timpson N.J. (Nicholas)
- Tobias J.H. (Jon)
- Uitterlinden A.G. (André)
- Warrington N.M. (Nicole)
- Williams F.M. (Frances)
- Wolber L.E. (Lisa)
- Zillikens M.C. (Carola)
- Publication venue
- 'Public Library of Science (PLoS)'
- Publication date
- 01/01/2014
- Field of study
Heritability of bone mineral density (BMD) varies across skeletal sites, reflecting different relative contributions of genetic and environmental influences. To quantify the degree to which common genetic variants tag and environmental factors influence BMD, at different sites, we estimated the genetic (rg) and residual (re) correlations between BMD measured at the upper limbs (UL-BMD), lower limbs (LL-BMD) and skull (SK-BMD), using total-body DXA scans of ~4,890 participants recruited by the Avon Longitudinal Study of Parents and their Children (ALSPAC). Point estimates of rg indicated that appendicular sites have a greater proportion of shared genetic architecture (LL-/UL-BMD rg = 0.78) between them, than with the skull (UL-/SK-BMD rg = 0.58 and LL-/SK-BMD rg = 0.43). Likewise, the residual correlation between BMD at appendicular sites (re = 0.55) was higher than the residual correlation between SK-BMD and BMD at appendicular sites (re = 0.20-0.24). To explore the basis fo
Experience with Chisl, a Configurable Hierarchical Interface Specification Language
- Publication venue
- 'Wiley'
- Publication date
- Field of study
A Manifesto for Hypermedia Usability Research
- Author
- BENEST I.D.
- BORGMAN C.L.
- BORGMAN C.L.
- CARD S.K.
- CARROLL J.M.
- CHIGNELL M.H.
- CONKLIN J.
- EBERTS R.
- EGAN D.E.
- EWING J.
- FAIRCHILD K.M.
- FAIRCHILD K.M.
- FOLEY J.D.
- GUINDON R.
- HALASZ F.G.
- HALASZ F.G.
- HALASZ F.G.
- HAMMOND N.
- HAMMOND N.
- HARDMAN L.
- HAYES P.J.
- HEPPE D.L.
- HOEY M.
- HUTCHINS E.L.
- HUTCHINS E.L.
- JONES W.P.
- JONES W.P.
- KELLY M.J.
- KOH T.T.
- MANTEI M.
- McKNIGHT C.
- MONK A.F.
- MONK A.F.
- MURRAY D.
- NIELSEN J.
- OCHSMAN R.B.
- PAYNE S.
- PRESS L.
- ROSCH E.
- ROSCH E.
- RUMELHART D.E.
- SALOMON G.
- SALTON G.
- SCAPIN D.L.
- SCHEGLOFF E.
- SHNEIDERMAN B.
- SHNEIDERMAN B.
- SIMPSON A.
- SMITH R.B.
- SPERBER D.
- TAYLOR M.M.
- TAYLOR M.M.
- TRIGG R.H.
- WATERWORTH J.A.
- WATERWORTH J.A.
- WATERWORTH J.A.
- WEYER S.A.
- WEYER S.A.
- WHALEN T.
- WINOGRAD T.
- WRIGHT P.
- YODER E.
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Thyroid Pathology
- Author
- A. Khan
- A. Lupi
- A. Machens
- A. Machens
- A. Nasir
- A. Nassar
- A. Rios
- A. Ruter
- A. Ryska
- A. Stojadinovic
- A.A. Al-Mulhim
- A.A. Renshaw
- A.B. Kramer
- A.K. Lam
- A.K. Sarda
- A.M. Avram
- A.M. Moody
- A.P. Weetman
- A.T. Ahuja
- B. Matsuura
- B.M. Weiss
- B.M. Wenig
- C. Cha
- C. Eng
- C. Ensinger
- C. Hedinger
- C. Imai
- C. Passler
- C.C. Cheung
- C.E. Anderson
- C.S. Heffess
- C.S. Leung
- Chintamani
- D. Giuffrida
- D. Giuffrida
- D. MacDermed
- D. Massi
- D.E. Burstein
- D.J. Powell Jr.
- D.L. Segev
- D.M. Dorfman
- D.S. Cooper
- E. Liberman
- E. Ogawa
- E. Williams
- E. Williams
- E. Yutan
- E.L. Mazzaferri
- F. Cortese
- F. Martinez
- F. Matsuzuka
- G. Bahar
- G. Fadda
- G. Lupoli
- G. Papi
- G. Tallini
- G.A. Derringer
- G.A. Thomas
- G.H. Daniels
- G.M. Sclabas
- H. Chen
- H. Chen
- H. Harms
- H. Heppe
- H.J. Baskin
- H.M. Ko
- H.R. Harach
- H.R. Tollefsen
- I. Bongarzone
- I. Brook
- I. Rodriguez
- I.B. Rosen
- I.D. Hay
- I.H. Mohammed
- J. Chan
- J. Feilchenfeldt
- J. Goellner
- J. LaGuette
- J. Rosai
- J. Rosai
- J. Soares
- J.B. Cohen
- J.D. Zajac
- J.K. Chan
- J.K. Chan
- J.M. Cerutti
- K. Okon
- K.M. Trokoudes
- K.T. Chem
- K.T. Mai
- K.Y. Lam
- L. Castro-Gomez
- L. Pantanowitz
- L. Souhami
- L. Su
- L.D. Dahl
- L.D. Thompson
- L.E. Holm
- L.H. Liu
- L.J. Layfield
- L.R. Ylagan
- L.R. Ylagan
- M. Berho
- M. Derwahl
- M. Dietlein
- M. Kihara
- M. Kojima
- M. Miyakawa
- M. Nair
- M. Papotti
- M. Pasquale Di
- M. Petersen
- M. Piersanti
- M. Ridder De
- M. Salvatori
- M. Santoro
- M. Ustun
- M. Volante
- M.K. Nakhjavani
- M.L. Carcangiu
- M.L. Carcangiu
- M.L. Carcangiu
- M.L. Carcangiu
- M.M. Nakhjavani
- M.N. Nikiforova
- M.N. Nikiforova
- M.R. Castro
- M.R. Pelizzo
- M.S. Hirsch
- N.M. Diaz
- N.R. Kim
- N.S. Deshmukh
- N.V. Egsgaard
- N.W. Thompson
- O. Sari
- P. Milde
- P. Sharma
- P.A. Kirby
- R. Chetty
- R. Elisei
- R. Nayar
- R. Nishimura
- R. Volpe
- R. Volpe
- R. Volpe
- R.B. Kovacs
- R.D. Craver
- R.H. Caplan
- R.H. Nishiyama
- R.V. Lloyd
- S. al-Dousary
- S. Fukata
- S. Guyetant
- S. Haraguchi
- S. Logani
- S. Orell
- S. Takashima
- S. Widder
- S.B. Kesmodel
- S.E. Naghavi
- S.E. Pambuccian
- S.F. Lax
- S.J. DiBiase
- S.J. Hewavisenthi
- S.L. Sugg
- S.M. Chow
- S.M. Jhiang
- S.M. Paproski
- S.P. Hodak
- S.R. Kini
- T. Kabalak
- T. Pisani
- T.C. Putti
- T.M. Duininck
- T.R. Miller
- U. Raghavan
- U. Rauhofer
- V. Fatourechi
- V. LiVolsi
- V. Maximo
- V. Triggiani
- V. Volsi Li
- V.A. LiVolsi
- V.A. LiVolsi
- W. Lang
- Y. Mizukami
- Y. Mizukami
- Y. Mizukami
- Y. Nikiforov
- Y. Nikiforov
- Y.C. Kon
- Y.E. Nikiforov
- Z. Baloch
- Z.W. Baloch
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2006
- Field of study
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