30 research outputs found

    Team 2: Situation Awareness of an Infantry Unit in a Chemical Environment

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    from Scythe : Proceedings and Bulletin of the International Data Farming Community, Issue 2 Workshop 14The German Federal Office of Defense Technology and Procurement has been analyzing the influence of networked sensors and effectors on military capabilities. The background of our overall scenario is peace support operations (PSO) in an urban environment. The background for the actual technical evaluations of sensors, effectors and the connecting network is the following scenario vignette: Convoy Protection

    Identification of motifs that function in the splicing of non-canonical introns

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    The enrichment of specific intronic splicing enhancers upstream of weak PY tracts suggests a novel mechanism for intron recognition that compensates for a weakened canonical pre-mRNA splicing motif

    A SUMMARY OF DATA FROM THE ATRC EXPERIMENTAL PROGRAM.

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    Precision medicine trials.

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    <p>Our proposed clinical trial framework for precision medicine consists of selecting a data collection, processing and model-based decision-making protocol, then testing the entire joint protocol in a classical trial setting.</p

    Physiological random processes in precision cancer therapy

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    <div><p>Many different physiological processes affect the growth of malignant lesions and their response to therapy. Each of these processes is spatially and genetically heterogeneous; dynamically evolving in time; controlled by many other physiological processes, and intrinsically random and unpredictable. The objective of this paper is to show that all of these properties of cancer physiology can be treated in a unified, mathematically rigorous way via the theory of random processes. We treat each physiological process as a random function of position and time within a tumor, defining the joint statistics of such functions via the infinite-dimensional characteristic functional. The theory is illustrated by analyzing several models of drug delivery and response of a tumor to therapy. To apply the methodology to precision cancer therapy, we use maximum-likelihood estimation with Emission Computed Tomography (ECT) data to estimate unknown patient-specific physiological parameters, ultimately demonstrating how to predict the probability of tumor control for an individual patient undergoing a proposed therapeutic regimen.</p></div

    Reactivity measurements in the ETR critical facility /

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    "Reactors-General ; TID-4500, (13th Ed., Rev.)"--Cover."July 10, 1958"--Cover.Caption title.Includes bibliographical references (leaf 21).Work Performed by Phillips Petroleum Company for the Atomic Energy CommissionMode of access: Internet

    TOC curves.

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    <p>An illustration of a Therapy Operating Characteristic (TOC) curve. (a) Schematic plot of Tumor-Control Probability (TCP) and Normal-Tissue-Complication Probability (NTCP) vs. injected mass of drug, <i>M</i> (arbitrary units); (b) The TOC curve: Plot of TCP vs. NTCP as <i>M</i> is varied.</p
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