436 research outputs found

    Similarity analysis of three dimensional nanofluid flow by deductive group theoretic method

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    The objective of this paper is to obtain similarity solution of three-dimensional nanofluid flow over flat surface stretched continuously in two lateral directions. Two independent variables from governing equations are reduced by applying deductive two parameter group theoretical method. Partial differential equations with boundary conditions are converted into ordinary differential equations with appropriate boundary conditions. Obtained equations are solved for temperature and velocity. The effect of nanoparticles volume fraction on temperature and velocity profile is investigated

    Local Non-Similar Solution of Powell-Eyring Fluid flow over a Vertical Flat Plate

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    Our objective is to obtain the non-similarity solution of non-Newtonian fluid for Powell-Eyring model by a local non-similarity method. Here, free stream velocity is considered in power-law form (=m). The governing equations are transformed using non-similar transformations and derived equations are treated as ordinary differential equations. Non-similar solutions are obtained for different values of power-law index and stream-wise location . Influence of various parameters on velocity and temperature field are presented graphically using MATLAB bvp4c solver

    Comparative study of oxytocin bolus and oxytocin infusion during caesarean section

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    Background: The incidence of postpartum haemorrhage varies from 2-11%. Postpartum haemorrhage complicates approximately 4% of deliveries in most large obstetric services. Postpartum haemorrhage is the third major cause of maternal mortality next to pregnancy induce hypertension (pre-eclampsia) and infection. Prevention, early recognition and prompt appropriate intervention are keys to minimizing its impact. Conventionally loss of more than 500 ml of blood following vaginal delivery and 1000 ml of blood following caesarean section is defined as postpartum haemorrhage. In this study we compared the efficacy of intravenous oxytocin bolus (2 IU) dose followed by infusion (160 mIU/minute) and only i.v. oxytocin infusion following delivery of fetus in elective and emergency LSCS with regard to uterine tone.Methods: This study was a prospective observational study. 200 low risk patients scheduled to undergo elective and emergency caesarean section under spinal anaesthesia in Department of obstetrics and gynecology, SSMC, Tumkur. Group A included i.v. bolus + i.v. injection, group B: i.v. infusion.Results: There was significant drop in haemoglobin and PCV in both group A and group B. But it was comparable among two groups. At 15th minute MBP was 77.2 mm of Hg and 80.04 mm of Hg in Group B. In group A better uterine tone was achieved earlier compared to group B at 2, 5, 10, 20 minutes.Conclusions: It was concluded from this study that oxytocin i.v. bolus with infusion causes earlier attainment of better uterine tone when compared with only infusion

    Effect of Storage Conditions on Free Radical Scavenging Activities of Crude Plant Material of Piper longum

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    Crude plant material of Piper longum was used for stability studies and kept in stability chambers. The effect of the stored samples on free radical scavenging activity was examined by DPPH, ABTS radical scavenging assays and Deoxyribose degradation assay. Various parameters used for the stability studies were 400C and 75% relative humidity in case of accelerated studies and 30°C and 65% relative humidity in case of long term studies as per ICH guidelines. Real time studies samples were stored at ambient temperature. Samples were taken out at periodic intervals and suspended in Tris-HCl buffer (10Mm, pH 6.5) to check the total phenolic content and free radical scavenging activity. Outcome of the antioxidant assays indicated that the samples of long term studies showed better antioxidant activity and higher total phenolic content than the samples of accelerated and real time studies

    Novel Proposed Work for Empirical Word Searching in Cloud Environment

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    People's lives have become much more convenient as a result of the development of cloud storage. The third-party server has received a lot of data from many people and businesses for storage. Therefore, it is necessary to ensure that the user's data is protected from prying eyes. In the cloud environment, searchable encryption technology is used to protect user information when retrieving data. The versatility of the scheme is, however, constrained by the fact that the majority of them only offer single-keyword searches and do not permit file changes.A novel empirical multi-keyword search in the cloud environment technique is offered as a solution to these issues. Additionally, it prevents the involvement of a third party in the transaction between data holder and user and guarantees integrity. Our system achieves authenticity at the data storage stage by numbering the files, verifying that the user receives a complete ciphertext. Our technique outperforms previous analogous schemes in terms of security and performance and is resistant to inside keyword guessing attacks.The server cannot detect if the same set of keywords is being looked for by several queries because our system generates randomized search queries. Both the number of keywords in a search query and the number of keywords in an encrypted document can be hidden. Our searchable encryption method is effective and protected from the adaptive chosen keywords threat at the same time

    DESIGN, SYNTHESIS AND VALIDATION OF CqsS RECEPTOR AGONIST TO MODULATE THE QUORUM SENSING CIRCUIT OF VIBRIO CHOLERAE–A MOLECULAR MIMIC THERAPY

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    Objective: Our earlier studies have characterized a compound from Melia dubia leaves, 4-ethyl resorcinol as an agonist of the Quorum Sensing (QS) receptor, CqsS agonist that had reverse engineered the QS circuit of V. cholerae from low-density to high-density state to effectively inhibit biofilm and enhance the production of protease to detach itself form the host tissue. So, the objective of this study was to synthesize structural derivatives of 4-ethyl resorcinol, to enhance its activity and to down regulate the host cell toxicity was validated.Methods: The antimicrobial (cell-density) and anti-virulent (protease, hemolysis, stress responds and biofilm inhibition) properties of the structural derivatives of 4-ethyl resorcinol were performed.Results: The results indicate that the compound has up surged protease expression along with a remarkable decrease in hemolytic activity at the 7th hour. The stress responds in treated culture has a higher survival rate while the bacterial cells in the control succumb to stress stating the potential of the drug to induce HCD (high cell density) condition in the LCD (low cell density) state. From CLSM analysis we state that there was significant amount of dead colonies and disrupted biofilm in the respective treated cultureConclusion: This could possibly open up a direction to curb the bacterial biofilm formation and may also turn out to be a potent drug against treating Vibrio cholerae infection at an early pointÂ

    Stability Studies of Crude Plant Material of Bacopa monnieri and Its Effect on Free Radical Scavenging Activity

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    Stability study of the crude plant material of Bacopa monnieri has been carried out as per ICH guidelines and its effect on free radical scavenging activity was studied by DPPH, ABTS radical scavenging assays and Deoxyribose degradation assay. The dried whole plant material of B. monnieri was kept in stability chambers at 40°C and 75% relative humidity in case of accelerated studies and at 30°C and 65% relative humidity for long term studies. Real time studies samples were stored at room temperature. Samples were taken out at periodic intervals, extracted in methanol to observe the HPTLC profiles and to study free radical scavenging activity. Results of antioxidant assays indicated that the samples of long term studies showed better antioxidant activity than the samples of accelerated and real time studies. Key words: Brahmi; accelerated study; long term study; real time study; free radical scavenging activity Abbreviations: BM: Bacopa monnieri; AS: Accelerated studies; LS: Long term studies; RT Real time studiesPratibha Srivastava et al. Stability Studies of Crude Plant Material of Bacopa monnieri and Its Effect on Free Radical Scavenging Activity. J Phytol 2/8 (2010) 103-109

    Presearch Data Conditioning in the Kepler Science Operations Center Pipeline

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    We describe the Presearch Data Conditioning (PDC) software component and its context in the Kepler Science Operations Center (SOC) pipeline. The primary tasks of this component are to correct systematic and other errors, remove excess flux due to aperture crowding, and condition the raw flux light curves for over 160,000 long cadence (~thirty minute) and 512 short cadence (~one minute) targets across the focal plane array. Long cadence corrected flux light curves are subjected to a transiting planet search in a subsequent pipeline module. We discuss the science algorithms for long and short cadence PDC: identification and correction of unexplained (i.e., unrelated to known anomalies) discontinuities; systematic error correction; and excess flux removal. We discuss the propagation of uncertainties from raw to corrected flux. Finally, we present examples of raw and corrected flux time series for flight data to illustrate PDC performance. Corrected flux light curves produced by PDC are exported to the Multi-mission Archive at Space Telescope [Science Institute] (MAST) and will be made available to the general public in accordance with the NASA/Kepler data release policy
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