Mean outcome distribution according to genotype and phenotype.

*<p>Surgery for necrotizing enterocolitis.</p

Hypertrophy and hypotrophy and clinical data in German vlbw infant population.

<p>Hypertrophy and hypotrophy and clinical data in German vlbw infant population.</p

Outcome of patients in microclusters of blood-culture proven sepsis.

<p><b>Legend:</b> IVH intraventricular haemorrhage; Surgery for PDA Patent Ductus arteriosus, NEC necrotizing enterocolitis, FIP focal intestinal perforation, ROP retinopathy of prematurity (kryo- or laser therapy); BPD bronchopulmonary dysplasia; severe complication: IVH grade IV, posthaemorrhagic hydrocephalus with need for VP shunt, periventricular leukomalacia, surgery for NEC/FIP or ROP and BPD;</p><p>p-values were derived from chi-square test if not otherwise indicated (* Mann-Whitney-U test comparing linked cases vs. first patient in cluster.</p

Pathogenic spectrum of blood-culture proven sepsis episodes.

*<p>Estimate: estimated risk for specific pathogen/100 cases of blood-culture proven sepsis.</p

Clinical characteristics of the VLBW cohort stratified to occurrence of late-onset sepsis (LOS).

<p><b>Legend:</b> PPROM Preterm premature rupture of membranes, C/section Caesarean section, SGA small-for-gestational-age (<10th Voigt percentile).</p><p># p-values were derived from chi-square test if not otherwise indicated (* Mann-Whitney-U test).</p