5,505 research outputs found
Five to ten-year results of the Birmingham Hip Resurfacing implant in the U.S.: A single institution\u27s experience
Atlas Data-Challenge 1 on NorduGrid
The first LHC application ever to be executed in a computational Grid
environment is the so-called ATLAS Data-Challenge 1, more specifically, the
part assigned to the Scandinavian members of the ATLAS Collaboration. Taking
advantage of the NorduGrid testbed and tools, physicists from Denmark, Norway
and Sweden were able to participate in the overall exercise starting in July
2002 and continuing through the rest of 2002 and the first part of 2003 using
solely the NorduGrid environment. This allowed to distribute input data over a
wide area, and rely on the NorduGrid resource discovery mechanism to find an
optimal cluster for job submission. During the whole Data-Challenge 1, more
than 2 TB of input data was processed and more than 2.5 TB of output data was
produced by more than 4750 Grid jobs.Comment: Talk from the 2003 Computing in High Energy Physics and Nuclear
Physics (CHEP03), La Jolla, Ca, USA, March 2003, 7 pages, 3 ps figure
Glucose metabolism and oscillatory behavior of pancreatic islets
A variety of oscillations are observed in pancreatic islets.We establish a
model, incorporating two oscillatory systems of different time scales: One is
the well-known bursting model in pancreatic beta-cells and the other is the
glucose-insulin feedback model which considers direct and indirect feedback of
secreted insulin. These two are coupled to interact with each other in the
combined model, and two basic assumptions are made on the basis of biological
observations: The conductance g_{K(ATP)} for the ATP-dependent potassium
current is a decreasing function of the glucose concentration whereas the
insulin secretion rate is given by a function of the intracellular calcium
concentration. Obtained via extensive numerical simulations are complex
oscillations including clusters of bursts, slow and fast calcium oscillations,
and so on. We also consider how the intracellular glucose concentration depends
upon the extracellular glucose concentration, and examine the inhibitory
effects of insulin.Comment: 11 pages, 16 figure
Recommended from our members
Self-care habits among people who inject drugs with skin and soft tissue infections: a qualitative analysis.
BACKGROUND:Injection drug use is on the rise in the USA, and skin and soft tissue infections (SSTI) are a common complication, resulting in significant morbidity and mortality. Due to structural barriers to care-seeking, many people who inject drugs avoid formal care and resort to self-care techniques, but little is known about the nature of these techniques, or more generally about the accuracy or breadth of this population's knowledge of SSTIs. METHODS:Semi-structured qualitative interviews were conducted with 12 people who inject heroin in two metropolitan areas: Sacramento and Boston, USA. RESULTS:These interviews reveal a robust and accurate knowledge base regarding skin infections, including the progression from simple cellulitis to an abscess, and acknowledgment of the possibility of serious infections. Nonetheless, there remains a reticence to seek care secondary to past traumatic experiences. A step-wise approach to self-care of SSTI infections was identified, which included themes of whole-body health, topical applications, use of non-prescribed antibiotics, and incision and drainage by non-medical providers. CONCLUSIONS:The reported SSTI self-care strategies demonstrate resilience and ingenuity, but also raise serious concerns about inappropriate antibiotic consumption and complications of invasive surgical procedures performed without proper training, technique, or materials. Harm reduction agencies and health care providers should work to obviate the need for these potentially dangerous practices by improving healthcare access for this population. In the absence of robust solutions to meet the needs of this population, education materials should be developed to optimize the efficacy and minimize the harms of these practices, while empowering and supporting the autonomy of people who use drugs and providing clear guidance on when self-care should be abandoned in favor of formal medical care
Quasiparticle properties of a coupled quantum wire electron-phonon system
We study leading-order many-body effects of longitudinal optical (LO) phonons
on electronic properties of one-dimensional quantum wire systems. We calculate
the quasiparticle properties of a weakly polar one dimensional electron gas in
the presence of both electron-phonon and electron-electron interactions. The
leading-order dynamical screening approximation (GW approximation) is used to
obtain the electron self-energy, the quasiparticle spectral function, and the
quasiparticle damping rate in our calculation by treating electrons and phonons
on an equal footing. Our theory includes effects (within the random phase
approximation) of Fermi statistics, Landau damping, plasmon-phonon mode
coupling, phonon renormalization, dynamical screening, and impurity scattering.
In general, electron-electron and electron-phonon many-body renormalization
effects are found to be nonmultiplicative and nonadditive in our theoretical
results for quasiparticle properties.Comment: 21 pages, Revtex, 12 figures enclose
Thermally Driven Electronic Topological Transition in FeTi
Ab initio molecular dynamics, supported by inelastic neutron scattering and nuclear resonant inelastic x-ray scattering, showed an anomalous thermal softening of the M^â_5 phonon mode in B2-ordered FeTi that could not be explained by phonon-phonon interactions or electron-phonon interactions calculated at low temperatures. A computational investigation showed that the Fermi surface undergoes a novel thermally driven electronic topological transition, in which new features of the Fermi surface arise at elevated temperatures. The thermally induced electronic topological transition causes an increased electronic screening for the atom displacements in the M^â_5 phonon mode and an adiabatic electron-phonon interaction with an unusual temperature dependence
Phonons and elasticity of cementite through the Curie temperature
Phonon partial densities of states (pDOS) of ^(57)Fe_3 C were measured from cryogenic temperatures through the Curie transition at 460 K using nuclear resonant inelastic x-ray scattering. The cementite pDOS reveal that low-energy acoustic phonons shift to higher energies (stiffen) with temperature before the magnetic transition. This unexpected stiffening suggests strongly nonharmonic vibrational behavior that impacts the thermodynamics and elastic properties of cementite. Density functional theory calculations reproduced the anomalous stiffening observed experimentally in cementite by accounting for phonon-phonon interactions at finite temperatures. The calculations show that the low-energy acoustic phonon branches with polarizations along the [010] direction are largely responsible for the anomalous thermal stiffening. The effect was further localized to the motions of the Fe_(II) site within the orthorhombic structure, which participates disproportionately in the anomalous phonon stiffening
Pure phonon anharmonicity and the anomalous thermal expansion of silicon
Despite the widespread use of silicon in modern technology, its peculiar thermal expansion is not well-understood. Harmonic phonons adapted to the specific volume at temperature, quasiharmonic approximation, has become accepted for simulating the thermal expansion, but has given ambiguous interpretations for microscopic mechanisms. To test the atomistic mechanisms, we performed inelastic
neutron scattering experiments on a single crystal of silicon to measure the changes in lattice dynamics
from 100 to 1500 K. Our state-of-the-art ab initio calculations, which fully account for phonon anharmonicity, reproduced the measured shifts of individual phonons with temperature, whereas the quasiharmonic approximation typically gave results of the wrong sign. Surprisingly, the accepted quasiharmonic model was found to predict the thermal expansion owing to a fortuitous cancellation of
contributions from individual phonons
Nuclear quantum effect with pure anharmonicity and the anomalous thermal expansion of silicon
Despite the widespread use of silicon in modern technology, its peculiar thermal expansion is not well understood. Adapting harmonic phonons to the specific volume at temperature, the quasiharmonic approximation, has become accepted for simulating the thermal expansion, but has given ambiguous interpretations for microscopic mechanisms. To test atomistic mechanisms, we performed inelastic neutron scattering experiments from 100 K to 1,500 K on a single crystal of silicon to measure the changes in phonon frequencies. Our state-of-the-art ab initio calculations, which fully account for phonon anharmonicity and nuclear quantum effects, reproduced the measured shifts of individual phonons with temperature, whereas quasiharmonic shifts were mostly of the wrong sign. Surprisingly, the accepted quasiharmonic model was found to predict the thermal expansion owing to a large cancellation of contributions from individual phonons
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