Receiver operating characteristic curve of the average apparent diffusion coefficient for the detection of biliary atresia.

<p>The area under the ROC curve was 0.805±0.058 (<i>P</i><0.001) for ADC. With a cut-off value of 1.317×10⁻³ mm²/s, ADC reached a sensitivity of 75% and a specificity of 81.5% for the differential diagnosis of BA and non-BA.</p

Correlation of ADC or FA with fibrotic stages in the BA group (n = 32).

<p>Correlation of ADC or FA with fibrotic stages in the BA group (n = 32).</p

The least significant difference (LSD) of the ADC (×10⁻³ mm²/s) between fibrotic stages in the BA group (n = 32).

<p>The least significant difference (LSD) of the ADC (×10⁻³ mm²/s) between fibrotic stages in the BA group (n = 32).</p

Comparison of ADC or FA values between the BA and non-BA groups (n = 59).

<p>Comparison of ADC or FA values between the BA and non-BA groups (n = 59).</p

Measurement of the apparent diffusion coefficient and fractional anisotropy on diffusion tensor imaging reconstructed images.

<p>A 165-day-old female infant with biliary atresia. Three regions of interest were drawn on each original image (b = 0), and three consecutive images (A1, B1 and C1) above the hepatic porta were included. The mean ADC values were obtained from the nine total ROIs on the ADC map (A2, B2 and C2), and the mean FA values were obtained from the FA maps (A3, B3 and C3).</p

Comparison of the 3D-MRCP findings and the final diagnoses for 190 infants and neonates.

<p>Note: The data in the parentheses represent the number of cases confirmed by the indicated method. Abbreviations: IC, intraoperative cholangiography; CCT, cure after clinical therapy; LEPE, laparoscopic exploration and pathological examination; BA, biliary atresia; BS, biliary stenosis; IH, infantile hepatitis; CMVH, cytomegalovirus hepatitis; BMJ, breast milk jaundice; PJ, pathologic jaundice.</p

Biliary atresia in a 90-day-old female infant.

<p>3D-MRCP does not display the extrahepatic biliary ducts except for the cystic common bile duct (A). The infant undergoes intraoperative cholangiography and is confirmed as having type III BA (B).</p

Infantile hepatitis in a 52-day-old boy.

<p>The extrahepatic central biliary ducts (including the right, left, and common hepatic ducts) and common bile duct are visualized on 3D-MRCP (A), which is consistent with the intraoperative cholangiography (B).</p

Findings of IC, LEPE and CCT for the 190 patients.

<p>Note: ▴ represents how many cases were diagnosed for non-BA with 3D-MRCP.</p><p>*represents how many cases were diagnosed for BA with 3D-MRCP. Abbreviations: IC, intraoperative cholangiography; CCT, cure after clinical therapy; LEPE, laparoscopic exploration and pathological examination; BA, biliary atresia; BS, biliary stenosis; IH, infantile hepatitis; CMVH, cytomegalovirus hepatitis; BMJ, breast milk jaundice; PJ, pathologic jaundice.</p

Biliary atresia in a 76-day-old female infant.

<p>3D-MRCP does not display the extrahepatic central biliary ducts and common bile duct (A). Intraoperative cholangiography confirms a diagnosis type III BA (B).</p