Combined effect of CCND1 and COMT polymorphisms and increased breast cancer risk-0

<p><b>Copyright information:</b></p><p>Taken from "Combined effect of CCND1 and COMT polymorphisms and increased breast cancer risk"</p><p>http://www.biomedcentral.com/1471-2407/8/6</p><p>BMC Cancer 2008;8():6-6.</p><p>Published online 14 Jan 2008</p><p>PMCID:PMC2254632.</p><p></p> and population controls. Meta-analysis of reported case control studies in Caucasian breast cancer samples and population controls (which are in agreement with HWE)

Combined effect of CCND1 and COMT polymorphisms and increased breast cancer risk-1

<p><b>Copyright information:</b></p><p>Taken from "Combined effect of CCND1 and COMT polymorphisms and increased breast cancer risk"</p><p>http://www.biomedcentral.com/1471-2407/8/6</p><p>BMC Cancer 2008;8():6-6.</p><p>Published online 14 Jan 2008</p><p>PMCID:PMC2254632.</p><p></p> and population controls. Meta-analysis of reported case control studies in Caucasian breast cancer samples and population controls (which are in agreement with HWE)

Replication of most significant associations from the discovery set meta-analysis in the replication samples.

<p>Results are presented for those SNPs which remained associated in the same direction in the validation set as in the discovery set (adjusted for ER-status).</p><p>Replication of most significant associations from the discovery set meta-analysis in the replication samples.</p

Kaplan-Meier plots depicting breast cancer related survival in response to rs421379 genotypes in pooled POSH stage-1, HEBCS and POSH stage-2 samples.

<p>Kaplan-Meier plots depicting breast cancer related survival in response to rs421379 genotypes in pooled POSH stage-1, HEBCS and POSH stage-2 samples.</p

The G-Allele of SNP309 Associates with an Accelerated Age of Diagnosis of Non-Gender Specific Tumors in Female but not in Male p53 Mutation Carriers.

<p>(A) The bar graph depicts the bits of mutual information between the MDM2 SNP309 locus and the age of tumor onset in females and in males. The associated p-values are depicted below. The MDM2 SNP309 locus and the age of tumor diagnosis share significant mutual information only in females and not in males. Statistical significance is represented by the black labeling of the bar graph and the p-values depicted below. The cumulative incidence of all non-gender specific tumor types for both the individuals T/T in genotype (black squares) and T/G or G/G in genotype (grey diamonds) is plotted as a function of age for females (B) and males (C). A square or a diamond represents at least one individual.</p

Characteristics of three patient populations used to define MDM2 SNP309 as a modifier of tumorgenisis in p53-mutation carriers.

<p>Characteristics of three patient populations used to define MDM2 SNP309 as a modifier of tumorgenisis in p53-mutation carriers.</p

Additional file 5: Table S2. of A polymorphism in the base excision repair gene PARP2 is associated with differential prognosis by chemotherapy among postmenopausal breast cancer patients

Associations between SNP and breast cancer-specific mortality by radiotherapy for interactions showing p <0.1 (LRT)$ in the MARIE study and results of replication in BCAC studies. (DOCX 20 kb