Patient demographics.

<p>Where data for three groups are given, P values refer to probabilities that the parameter differs significantly between the 3 groups, otherwise the probabilities refer to differences between the two diabetic groups.</p>*<p>indicates a statistically significant p-value of ≤0.05.</p

Baseline data for well-controlled (HbA1c ≤7.5%) and poorly-controlled (HbA1c >7.5%) diabetic patients (including both T1DM and T2DM) for all ocular parameters.

<p>Aberrations were measured for 6 mm pupils.</p>*<p>indicates a statistically significant p-value of ≤0.05.</p

Mean change from baseline measurements for ocular parameters CCT, ACD, LT, and AL over time for each group (A) and the relative value of each parameter (i.e. the absolute value of the parameter divided by its baseline value) as a function of time (B).

<p>T2DM are represented as diamonds; T1DM are represented as squares; control subjects are represented as triangles. The error bars show ± SEM.</p

Mean changes over time in the components of refractive error (MSE, J0, and J45) from baseline measurements for each group.

<p>T2DM are represented as diamonds; T1DM are represented as squares; control subjects are represented as triangles. The error bars show ± SEM.</p

Change in blood glucose levels from baseline over time for each group.

<p>T2DM are represented as diamonds; T1DM are represented as squares; control subjects are represented as triangles. The error bars represent 1 standard error of the mean (SD/√n). Subjects ate their meals around 0900, 1330 and 1730 hours. Mean baseline blood glucose levels as determined with the Hemocue test were 11.1±5.0 mM/l (200±90 mg/dl) for the T1DM; 8.3±3.0 mM/l (149±54 mg/dl) for T2DM; and 4.6±0.5 mM/l (83±9 mg/dl) for the control subjects.</p