A Wrapper of PCI Express with FIFO Interfaces based on FPGA

This paper proposes a PCI Express (PCIE) Wrapper core named PWrapper with FIFO interfaces. Compared with other PCIE solutions, PWrapper has several advantages such as flexibility, isolation of clock domain, etc. PWrapper is implemented and verified on Vertex -5-FX70T which is a development board provided by Xilinx Inc. Architecture of PWrapper and design of two key modules are illustrated, which timing optimization methods have been adopted. Then we explained the advantages and challenges of on-chip interfaces technology based on FIFOs. The verification results show that PWrapper can achieve the speed of 1.8Gbps (Giga bits per second).Comment: 5 pages, 8 figure

Phase Separation and Chemical Inhomogeneity in the Iron Chalcogenide Superconductor Fe1+yTexSe1-x

We report investigation on Fe1+yTexSe1-x single crystals by using scanning transmission electron microscopy (STEM) and electron energy loss spectroscopy (EELS). Both nonsuperconducting samples with excess iron and superconducting samples demonstrate nanoscale phase separation and chemical inhomogeneity of Te/Se content, which we attribute to a miscibility gap. The line scan EELS technique indicates ~20% or less fluctuation of Te concentration from the nominal compositions

Survival benefit of local consolidative therapy for patients with single-organ metastatic pancreatic cancer: a propensity score-matched cross-sectional study based on 17 registries

BackgroundThe continuous exploration of oligometastatic disease has led to the remarkable achievements of local consolidative therapy (LCT) and favorable outcomes for this disease. Thus, this study investigated the potential benefits of LCT in patients with single-organ metastatic pancreatic ductal adenocarcinoma (PDAC).MethodsPatients with single-organ metastatic PDAC diagnosed between 2010 - 2019 were identified from the Surveillance, Epidemiology, and End Results (SEER) database. Propensity score matching (PSM) was performed to minimize selection bias. Factors affecting survival were assessed by Cox regression analysis and Kaplan-Meier estimates.ResultsA total of 12900 patients were identified from the database, including 635 patients who received chemotherapy combined with LCT with a 1:1 PSM with patients who received only chemotherapy. Patients with single-organ metastatic PDAC who received chemotherapy in combination with LCT demonstrated extended median overall survival (OS) by approximately 57%, more than those who underwent chemotherapy alone (11 vs. 7 months, p < 0.001). Furthermore, the multivariate Cox regression analysis revealed that patients that received LCT, younger age (< 65 years), smaller tumor size (< 50 mm), and lung metastasis (reference: liver) were favorable prognostic factors for patients with single-organ metastatic PDAC.ConclusionThe OS of patients with single-organ metastatic pancreatic cancer who received LCT may be prolonged compared to those who received only chemotherapy. Nevertheless, additional prospective randomized clinical trials are required to support these findings

Localization of ultrasound in a three-dimensional elastic network

After exactly half a century of Anderson localization, the subject is more alive than ever. Direct observation of Anderson localization of electrons was always hampered by interactions and finite temperatures. Yet, many theoretical breakthroughs were made, highlighted by finite-size scaling, the self-consistent theory and the numerical solution of the Anderson tight-binding model. Theoretical understanding is based on simplified models or approximations and comparison with experiment is crucial. Despite a wealth of new experimental data, with microwaves, light, ultrasound and cold atoms, many questions remain, especially for three dimensions. Here we report the first observation of sound localization in a random three-dimensional elastic network. We study the time-dependent transmission below the mobility edge, and report ``transverse localization'' in three dimensions, which has never been observed previously with any wave. The data are well described by the self-consistent theory of localization. The transmission reveals non-Gaussian statistics, consistent with theoretical predictions.Comment: Final published version, 5 pages, 4 figure