5 research outputs found
Pharmacokinetics and tissue biodistribution of iniparib and selected metabolites in the tumor-bearing dog.
<p>Pharmacokinetics and tissue biodistribution of iniparib and selected metabolites in the tumor-bearing dog.</p
Iniparib Dose Escalation cohorts in tumor bearing dogs.
<p>Iniparib Dose Escalation cohorts in tumor bearing dogs.</p
Schedule of patient evaluations and study procedures.
<p>Schedule of patient evaluations and study procedures.</p
Disease Free Interval.
<p>Kaplan-Meier disease-free interval (DFI) curves comparing dogs treated with toceranib to control dogs. Hash marks denote censored observations; n = 63 toceranib-treated dogs; n = 63 control dogs. (A) Intent-to-treat analysis (p = 0.274). (B) Adherence analysis (p = 0.3).</p
Overall Survival.
<p>Kaplain-Meier overall survival (OS) curves comparing toceranib-treated dogs with control dogs. Hash marks denote censored observations; n = 63 toceranib-treated dogs; n = 63 control dogs (p = 0.08).</p