5,309 research outputs found

    Comment on "Chiral Suppression of Scalar Glueball Decay"

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    Comment on ``Chiral Suppression of Scalar Glueball Decay''Comment: Comment published in Phys. Rev. Lett. 98, 149103(2007

    Variation of Mycobacterium tuberculosis antigen-specific IFN-γ and IL-17 responses in healthy tuberculin skin test (TST)-positive human subjects.

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    ObjectiveTo determine the variation of IFN-γ and IL-17 responses to M. tuberculosis antigens in healthy TST+ humans.MethodsWe isolated peripheral blood mononuclear cells from 21 TST+ healthy adults, stimulated them with phytohemagglutinin (PHA), PPD, Ag85B, ESAT-6, and live M. bovis BCG, and assayed IFN-γ and IL-17 secretion by ELISA in supernatants after 24 or 72 hours of incubation respectively.ResultsAs in other studies, we found a wide range of IFN-γ responses to M. tuberculosis antigens; the variation significantly exceeded that observed in the same donors to the polyclonal T cell stimulus, phytohemagglutinin (PHA). In addition, we assayed IL-17 secretion in response to the same stimuli, and found less subject-to-subject variation. Analysis of the ratio of IFN-γ to IL-17 secretion on a subject-to-subject basis also revealed a wide range, with the majority of results distributed in a narrow range, and a minority with extreme results all of which were greater than that in the majority of subjects. The data suggest that study of exceptional responses to M. tuberculosis antigens may reveal immunologic correlates with specific outcomes of M. tuberculosis infection.ConclusionVariation of IFNγ and IFN-γ/IL-17 responses to mycobacterial antigens exceeds that of responses to the polyclonal stimulus, PHA, in TST positive healthy humans. This indicates a quantitative spectrum of human immune responses to infection with M. tuberculosis. Since the outcome of human infection with M. tuberculosis varies greatly, systematic study of multiple immune responses to multiple antigens is likely to reveal correlations between selected immune responses and the outcomes of infection

    (Z)-Ethyl 3-(2,4-difluoro­anilino)-2-(4-methoxy­phen­yl)acrylate

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    The title compound, C18H17F2NO3, consists of three individually planar subunits, namely two benzene rings and one amino­acrylate group. The amino­acrylate group forms dihedral angles of 5.92 (7) and 50.21 (6)° with the difluoro and methoxy benzene rings, respectively. The dihedral angle between the two benzene rings is 55.25 (7)°. The mol­ecules exhibit intra­molecular N—H⋯O and N—H⋯F inter­actions and form a three-dimensional network via inter­molecular C—H⋯O and C—H⋯π hydrogen bonds

    Flat-band and multi-dimensional fermions in Pb10(PO4)6O4

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    Employing a combination of first-principles calculations and low-energy effective models, we present a comprehensive investigation on the electronic structure of Pb10_{10}(PO4_{4})6_{6}O4_{4}, which exhibits remarkable quasi-one-dimensional flat-band around the Fermi level that contains novel multi-dimensional fermions. These flat bands predominantly originate from px/pyp_x/p_y orbital of the oxygen molecules chain at 4e4e Wyckoff positions, and thus can be well-captured by a four-band tight-binding model. Furthermore, the abundant crystal symmetry inherent to Pb10_{10}(PO4_{4})6_{6}O4_{4} provides an ideal platform for the emergence of various multi-dimensional fermions, including a 0D four-fold degenerated Dirac fermion with quadratic dispersion, a 1D quadratic/linear nodal-line (QNL/LNL) fermion along symmetric kk-paths, 1D hourglass nodal-line (HNL) fermion linked to the Dirac fermion, and a 2D symmetry-enforced nodal surface (NS) found on the kzk_z=π\pi plane. Moreover, when considering the weak ferromagnetic order, Pb10_{10}(PO4_{4})6_{6}O4_{4} transforms into a rare semi-half-metal, which is characterized by the presence of Dirac fermion and HNL fermion at the Fermi level for a single spin channel exhibiting 100%\% spin polarization. Our findings reveal the coexistence of flat bands, diverse topological semimetal states and ferromagnetism within in Pb10_{10}(PO4_{4})6_{6}O4_{4}, which may provide valuable insights for further exploring intriguing interplay between superconductivity and exotic electronic states.Comment: 8 pages, 4 figure

    Bis(4-amino­benzene­sulfonato-κN)diaqua­bis(dimethyl­formamide-κO)nickel(II) dihydrate

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    In the title compound, [Ni(C6H6NO3S)2(C3H7NO)2(H2O)2]·2H2O, the NiII ion (site symmetry ) is coordinated by two –NH2 groups from two 4-amino­benzene­sulfonate anions, two O atoms from two dimethyl­formamide mol­ecules and two water mol­ecules, forming a slightly distorted trans-NiN2O4 octa­hedral geometry. In the crystal structure, inter­molecular O—H⋯O, O—H⋯(O,O) and N—H⋯O hydrogen bonds link the components into a three-dimensional network. The O atoms of the sulfonate group are disordered over two sets of sites in a 0.833 (4):0.167 (4) ratio and the O atom of the uncoordinated water mol­ecule is disordered over two sites in a 0.637 (18):0.363 (18) ratio
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