Latex Allergy In Health Care Workers

Background and Design: We aimed to determine the frequency of latex allergy in our hospital and to to evaluate the clinical and demographical features of the cases.Materials and Methods: A detailed questionnaire was administered to healthcare workers by a physician. Skin prick test with latex and patch test with rubber chemicals and a piece of latex glove were performed for all healthcare workers. Latex-specific IgE was measured in serum.Results: The study sample consisted of 36 nurses, 14 doctors, and 50 healthcare workers. While 46 subjects had symptoms, 54 subjects had no symptoms. The relationship of clinical disease with working duration, exposure duration (hour/day), history of atopy, and drug/food allergies was statistically significant. Five nurses and 1 healthcare worker had positive skin prick test. Two of them had positive latex-specific IgE. Positive skin prick test statistically significantly correlated with occupation, working duration, exposure duration (hour/day) and positive latex-specific IgE. Two nurses and 2 healthcare workers had positive latex-specific IgE. Two of them had positive skin prick test. Positive latexspecific IgE statistically significantly correlated with working duration, exposure duration, and positive skin prick test. Patch test with a piece of latex glove was negative in all subjects. Three healthcare workers had positive patch test with thiuram-mix, one of them had also positive patch test with mercaptobenzothiazole.Discussion: One of the risk factors for latex allergy is occupations involving frequent exposure to latex products. Latex allergy should be taken into consideration if type I hypersensitivity reactions occur in occupational groups at risk for anaphylactic reaction

Patch (PATCH) test results in patients with contact dermatitis

Uludağ Üniversitesi Tıp Fakültesi Dermatoloji Polikliniğine başvuran 66'sı kadın,34 ’ ü erkek, toplam 1UD kontakt dermatitli hastaya, ICDRE'un kabul ettiği sık rastlanan allerjenler ve çeşitli tıp dallarında kullanılan bazı maddelerden oluşan modifiye standart serimizle yama testi uyguladık. Hastaların yaş, cinsiyet,meslek, muhtemel kontaktan, hobileri, giyim-eşya özellikleri, ev ve çevre özellikleri, hastalık süresi, yerleşme yeri, deri bulguları dikkatle incelendi. Kontakt dermatitin çoğunlukla kadınlarda ve ikinci, üçüncü dekatlarda ortaya çıktığı, meslek Dİarak ev hanımlarının ilk sırayı aldığı görüldü. Allerjik reaksiyon saptadığımız 72 hastanın 54'ünde allerjen,hastaların bizzat bildirdikleri veya anamnezle saptanan muhtemel kontaktanla ilişkili idi. Bunlardan; meslek,hobiler, giyim ve eşyaların allerjik kontakt dermatitte rolü olduğu ev ve çevre özelliklerinin ise özellik arzetmediği görüldü. Hastalığın yerleşim yeri göz önünde bulundurulduğunda en çok ellerde lokalize olduğu, klinik tablo olarak 9D olguda akut ekzema şeklinde ortaya çıktığı gözlendi. Kadınlarda en çak reaksiyon veren madde (% AO) nikel sülfat idi ve her iki cinste toplam reaksiyonların, % 28'ini teşkil ediyordu. Ön sıralarda yer alan diğer aller-jenlerden potasyum dikromat (% 15.2), erkeklerde saptadığımız allerjik reaksiyonların da çoğunluğunu (% 2S) oluşturuyordu. Allerjik reaksiyonların % 12.7'si 4.gün yapılan ikinci değerlendirme sırasında saptandı. Diğer taraftan 15 madde ile ilk değerlendirmede şüpheli veya zayıf pozitif Dİan 122 reaksiyondan 56'sı ikinci değerlendirmede negatif bulundu

Blaşko çizgisini takip eden lineer sklerodermalı bir vaka

Linear scleroderma is a rare variant of localized scleroderma typically seen in children and localized in the extremities. A 21-year-old female patient had a well-defined, hyper-pigmented, sclerotic plaque on right half of the frontal trunk, starting from the breast and arcing up to the right arm, then continuing linearly with anti-nuclear antibody positivity in her laboratory results. Histopathology was compatible with scleroderma. She was diagnosed linear scleroderma. There is an ongoing argument on whether localized scleroderma follows Blaschko's lines or not. By presenting this case, we aimed to contribute to literature claiming that localized scleroderma may follow Blaschko's lines. © 2012 Düzce Medical Journal

A case of scleromyxedema without monoclonal gammopathy responded to treatment with IVIG

Lichen myxedematosus’’ is a primary inflammatory dermatosis characterized by fibroblast proliferation and mucin deposition in the skin. Scleromyxedema is the most frequent variant of lichen myxedematosus and is accompanied by papular lesions, diffuse sclerosis, and erythema. It is usually associated with paraproteinemias. Scleromyxedema without monoclonal gammopathy is a rare and atypical variant of lichen myxedematosus. Systemic involvement and sometimes fatal course can be seen with scleromyxedema. Although several treatment modalities have been tried as case reports for the disease, there isn’t any definitive treatment yet. Intravenous immunoglobulin’s mechanism of action in scleromyxedema is still not clear as well as etiopathogenesis of scleromyxedema. Herein we describe a scleromyxedema case without monoclonal gammopathy and his response to the treatment with intravenous immunoglobulin

Acroangiodermatitis in a below-knee amputation stump

WOS: 000292659600026PubMed: 21575039