21 research outputs found

    The Vehicle, Spring 2006

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    Table of Contents Inicio de TerminoJacob Fosterpage 1 Devoted FriendMaurice Tracypage 2 Bad Hair DaysGreg Coreypage 2 Shelf LifeJody Shootpage 3 AnointMaurice Tracypage 4 Understanding BlackAmanda Bushpage 5 My Uncle\u27s HouseCarissa Haydenpage 7 Try, And Save Your BreathGreg Coreypage 8 Solid AdviceAnthony Shootpage 8 Calligraphy / The Metamorphosis / Buttercup DragonflyGrey Harrellpage 9 Swinging FireMaurice Tracypage 11 Epitaph for a Man With No Name 1860-1892Dallas Schumacherpage 12 Untitled 71Ben Hartpage 13 Random Maunderings of a Ford Hall InsomniacJacob Fosterpage 14 Fat BangsLakisha Allenpage 15 I WantMaurice Tracypage 16 DiscoveryCarissa Haydenpage 17 Poverty SpongeChris Robinsonpage 18 Seedless GrapesAnthony Shootpage 19 Untitled 34Ben Hartpage 20 DiscoveryCarissa Haydenpage 21 drunk againAnthony Shootpage 22 SquareMaurice Tracypage 23 Let Me Just Say ThisJody Shootpage 24 passing a small cemetery after a stormAnthony Shootpage 25 Career DayMitch Jamespage 26 Art Submissions Beaded VaseBrandy Lee Bartercover The StrayBrandy Lee Barterpage 10 RapidsKristy Van Amerongenpage 10 UntitledKristy Van Amerongenpage 13 UntitledKristy Van Amerongenpage 15 A Quiet RoadBrandy Lee Barterpage 19 X Marks the SpotBrandy Lee Barterpage 20 An Old FriendBrandy Lee Barterpage 25 The Vehicle Staffpage 27 Contributorspage 28https://thekeep.eiu.edu/vehicle/1085/thumbnail.jp

    White Matter Hyperintensities in Vascular Contributions to Cognitive Impairment and Dementia (VCID): Knowledge Gaps and Opportunities

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    White matter hyperintensities (WMHs) are frequently seen on brain magnetic resonance imaging scans of older people. Usually interpreted clinically as a surrogate for cerebral small vessel disease, WMHs are associated with increased likelihood of cognitive impairment and dementia (including Alzheimer\u27s disease [AD]). WMHs are also seen in cognitively healthy people. In this collaboration of academic, clinical, and pharmaceutical industry perspectives, we identify outstanding questions about WMHs and their relation to cognition, dementia, and AD. What molecular and cellular changes underlie WMHs? What are the neuropathological correlates of WMHs? To what extent are demyelination and inflammation present? Is it helpful to subdivide into periventricular and subcortical WMHs? What do WMHs signify in people diagnosed with AD? What are the risk factors for developing WMHs? What preventive and therapeutic strategies target WMHs? Answering these questions will improve prevention and treatment of WMHs and dementia
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