20,155 research outputs found
ICF core sets for low back pain: do they include what matters to patients?
To investigate whether the International Classification of Functioning Disability and Health (ICF) Core Sets for low back pain encompass the key functional problems of patients
Compensatory Proliferation Induced by Cell Death in the Drosophila Wing Disc Requires Activity of the Apical Cell Death Caspase Dronc in a Nonapoptotic Role
Achieving proper organ size requires a balance between proliferation and cell death. For example, at least 40%–60% of cells in the Drosophila wing disc can be lost, yet these discs go on to give rise to normal-looking adult wings as a result of compensatory proliferation 1, 2, 3. The signals that drive this proliferation are unknown. One intriguing possibility is that they derive, at least in part, from the dying cells. To explore this hypothesis, we activated cell death signaling in specific populations of cells in the developing wing but prevented these cells from dying through expression of the baculovirus p35 protein, which inhibits the activity of effector caspases that mediate apoptosis [4]. This allowed us to uncouple the activation steps of apoptosis from death itself. Here we report that stimulation of cell death signaling in the wing disc—in the absence of cell death—results in increased proliferation and ectopic expression of Wingless, a known mitogen in the wing. Activation of the apical cell death caspase Dronc is necessary and sufficient to drive both of these processes. Our results demonstrate an unanticipated function, the nonautonomous induction of proliferation, of an apical cell death caspase. This activity is likely to contribute to tissue homeostasis by promoting local compensatory proliferation in response to cell death. We speculate that dying cells may communicate cell fate or behavior instructions to their neighbors in other contexts as well
Study-development of improved photointerpretative techniques to wheat identification
There are no author-identified significant results in this report
Event Analysis of Pulse-reclosers in Distribution Systems Through Sparse Representation
The pulse-recloser uses pulse testing technology to verify that the line is
clear of faults before initiating a reclose operation, which significantly
reduces stress on the system components (e.g. substation transformers) and
voltage sags on adjacent feeders. Online event analysis of pulse-reclosers are
essential to increases the overall utility of the devices, especially when
there are numerous devices installed throughout the distribution system. In
this paper, field data recorded from several devices were analyzed to identify
specific activity and fault locations. An algorithm is developed to screen the
data to identify the status of each pole and to tag time windows with a
possible pulse event. In the next step, selected time windows are further
analyzed and classified using a sparse representation technique by solving an
l1-regularized least-square problem. This classification is obtained by
comparing the pulse signature with the reference dictionary to find a set that
most closely matches the pulse features. This work also sheds additional light
on the possibility of fault classification based on the pulse signature. Field
data collected from a distribution system are used to verify the effectiveness
and reliability of the proposed method.Comment: Accepted in: 19th International Conference on Intelligent System
Application to Power Systems (ISAP), San Antonio, TX, 201
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Developmental changes in the germinability, desiccation tolerance, hardseededness, and longevity of individual seeds of Trifolium ambiguum
Background and Aims: Using two parental clones of outcrossing Trifolium ambiguum as a potential model system, we examined how during seed development the maternal parent, number of seeds per pod, seed position within the pod, and pod position within the inflorescence influenced individual seed fresh weight, dry weight, water content, germinability, desiccation tolerance, hardseededness, and subsequent longevity of individual seeds.
Methods: Near simultaneous, manual reciprocal crosses were carried out between clonal lines for two experiments. Infructescences were harvested at intervals during seed development. Each individual seed was weighed and then used to determine dry weight or one of the physiological behaviour traits.
Key Results: Whilst population mass maturity was reached at 33–36 days after pollination (DAP), seed-to-seed variation in maximum seed dry weight, when it was achieved, and when maturation drying commenced, was considerable. Individual seeds acquired germinability between 14 and 44 DAP, desiccation tolerance between 30 and 40 DAP, and the capability to become hardseeded between 30 and 47 DAP. The time for viability to fall to 50 % (p50) at 60 % relative humidity and 45 °C increased between 36 and 56 DAP, when the seed coats of most individuals had become dark orange, but declined thereafter. Individual seed f. wt at harvest did not correlate with air-dry storage survival period. Analysing survival data for cohorts of seeds reduced the standard deviation of the normal distribution of seed deaths in time, but no sub-population showed complete uniformity of survival period.
Conclusions: Variation in individual seed behaviours within a developing population is inherent and inevitable. In this outbreeder, there is significant variation in seed longevity which appears dependent on embryo genotype with little effect of maternal genotype or architectural factors
Tank tests to determine the effect of varying design parameters of planing-tail hulls II : effect of varying depth of step, angle of after- body keel, length of afterbody chine, and gross load
The second part of a series of tests made in Langley tank no. 2 to determine the effect of varying design parameters of planing-tail hulls is presented. Results are given to show the effects on resistance characteristics of varying angle of afterbody keel, depth of step, and length of afterbody chine. The effect of varying the gross load is shown for one configuration. The resistance characteristics of planing-tail hulls are compared with those of a conventional flying-boat hull. The forces on the forebody and afterbody of one configuration are compared with the forces on a conventional hull. Increasing the angle of afterbody keel had small effect on hump resistance and no effect on high-speed resistance but increased free-to-trim resistance at intermediate speeds. Increasing the depth of step increased hump resistance, had little effect on high-speed resistance, and increased free-to-trim resistance at intermediate speeds. Omitting the chines on the forward 25 percent of the afterbody had no appreciable effect on resistance. Omitting 70 percent of the chine length had almost no effect on maximum resistance but broadened the hump and increased spray around the afterbody. Load-resistance ratio at the hump decreased more rapidly with increasing load coefficient for the planing-tail hull than for the representative conventional hull, although the load-resistance ratio at the hump was greater for the planing-tail hull than for the conventional hull throughout the range of loads tested. At speeds higher than hump speed, load-resistance ratio for the planing-tail hull was a maximum at a particular gross load and was slightly less at heavier and lighter gross loads. The planing-tail hull was found to have lower resistance than the conventional hull at both the hump and at high speeds, but at intermediate speeds there was little difference. The lower hump resistance of the planing-tail hull was attributed to the ability of the afterbody to carry a greater percentage of the total load while maintaining a higher value of load-resistance ratio
Labeling research in support of through-the-season area estimation
The development of LANDSAT-based through-the-season labeling procedures for corn and soybeans is discussed. A model for predicting labeling accuracy within key time periods throughout the growing season is outlined. Two methods for establishing the starting point of one key time period, viz., early season, are described. In addition, spectral-temporal characteristics for separating crops in the early season time period are discussed
ARA Guide to opening a new cafeteria
In 1992 ARA had 39 business dining cafeterias open. In 1993 38 new cafeterias opened. These numbers not only represent openings, but new pieces of business for ARA. The opening is the first impression the customer gets of ARA; this makes it essential that the opening be a success. A successful opening is the beginning to a successful new piece of business. To assure a successful, organized opening, a standard manual is needed to guide the ARA operator. A successful opening is the mark of a successful future. If the appropriate policies and procedures are implemented from the start, the business will begin with a definite advantage. The manual developed will guide the operator and assist in implementing policies and procedures. The manual covers opening procedures including forming an opening team, how to staff and train employees for the operation, menu selection, and ordering food and equipment. An area not covered in the manual that the operator may need to be concerned with is government regulations which include such areas as building permits, health permits and fire department permits, all of which vary by location. Generally these are the responsibility of the clients and building contractors, but if permits are not obtained, the opening will not happen
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