1,704 research outputs found

    Charmonium properties from lattice QCD + QED: hyperfine splitting, J/ψJ/\psi leptonic width, charm quark mass and aμca_{\mu}^c

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    We have performed the first nf=2+1+1n_f = 2+1+1 lattice QCD computations of the properties (masses and decay constants) of ground-state charmonium mesons. Our calculation uses the HISQ action to generate quark-line connected two-point correlation functions on MILC gluon field configurations that include u/du/d quark masses going down to the physical point, tuning the cc quark mass from MJ/ψM_{J/\psi} and including the effect of the cc quark's electric charge through quenched QED. We obtain MJ/ψ−MηcM_{J/\psi}-M_{\eta_c} (connected) = 120.3(1.1) MeV and interpret the difference with experiment as the impact on MηcM_{\eta_c} of its decay to gluons, missing from the lattice calculation. This allows us to determine ΔMηcannihiln\Delta M_{\eta_c}^{\mathrm{annihiln}} =+7.3(1.2) MeV, giving its value for the first time. Our result of fJ/ψ=f_{J/\psi}= 0.4104(17) GeV, gives Γ(J/ψ→e+e−)\Gamma(J/\psi \rightarrow e^+e^-)=5.637(49) keV, in agreement with, but now more accurate than experiment. At the same time we have improved the determination of the cc quark mass, including the impact of quenched QED to give m‾c(3 GeV)\overline{m}_c(3\,\mathrm{GeV}) = 0.9841(51) GeV. We have also used the time-moments of the vector charmonium current-current correlators to improve the lattice QCD result for the cc quark HVP contribution to the anomalous magnetic moment of the muon. We obtain aμc=14.638(47)×10−10a_{\mu}^c = 14.638(47) \times 10^{-10}, which is 2.5σ\sigma higher than the value derived using moments extracted from some sets of experimental data on R(e+e−→hadrons)R(e^+e^- \rightarrow \mathrm{hadrons}). This value for aμca_{\mu}^c includes our determination of the effect of QED on this quantity, δaμc=0.0313(28)×10−10\delta a_{\mu}^c = 0.0313(28) \times 10^{-10}.Comment: Added extra discussion on QED setup, some new results to study the effects of strong isospin breaking in the sea (including new Fig. 1) and a fit stability plot for the hyperfine splitting (new Fig. 7). Version accepted for publication in PR

    Using participatory and creative methods to facilitate emancipatory research with people facing multiple disadvantage: a role for health and care professionals

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    Participatory and creative research methods are a powerful tool for enabling active engagement in the research process of marginalised people. It can be particularly hard for people living with multiple disadvantage, such as disabled people from ethnic minority backgrounds, to access research projects that are relevant to their lived experience. This article argues that creative and participatory methods facilitate the co-researchers’ engagement in the research process, which thus becomes more empowering. Exploring the congruence of these methods with their professional ethos, health and care professionals can use their skills to develop them further. Both theory and practice examples are presented

    Enhanced Support for High Intensity Users of the Criminal Justice System – an evaluation of mental health nurse input into Integrated Offender Management Services in the North East of England

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    The current UK Government’s focus on the development of services to manage and support offenders with mental health problems has resulted in a number of innovative project developments. This research examines a service development in the North East of England which co-located Mental Health nurses with two Integrated Offender Management teams. While not solving all problems, the benefits of co-location were clear – although such innovations are now at risk from government changes which will make Integrated Offender Management the responsibility of new providers without compelling them to co-operate with health services

    FeS-Induced Radical Formation and Its Effect on Plasmid DNA

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    Plasmid DNA was incubated at 25°C with aqueous solutions of dissolved Fe(II), S(-II), and nanoparticulate FeS with a mackinawite structure, FeSm. At ≥0.1 mM total dissolved Fe(II) and S(-II), an increase in the proportion of the relaxed plasmid DNA occurs, through scission of the DNA backbone. In solutions where FeSm was precipitated, nanoparticulate FeSm binds to the DNA molecules. In solutions with concentrations below the FeSm solubility product, nicking of supercoiled pDNA occurs. Plasmid DNA appears to be a sensitive proxy for radical reactions. The reactant is proposed to be a sulfur-based radical produced from the iron-catalyzed decomposition of bisulfide, in a manner analogous to the Fenton reaction. This is further supported by experiments that suggest that sulfide free radicals are produced during the photolysis of aqueous solutions of polysulfides. Supercoiling of DNA affects nearly all DNA–protein transactions so the observation of relaxation of supercoiled forms through reaction with FeS solutions has direct implications to biochemistry. The results of this experimentation suggest that genotoxicity in FeS-rich systems is a further contributory factor to the limited survival of organisms in sulfidic environments. Mutations resulting from the interactions of organisms and mobile elements, such as plasmids, in sediments will also be affected in sulfide-rich environments

    Reading and Phonological Skills in Boys with Fragile X Syndrome

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    Reading skills are critical for the success of individuals with intellectual disabilities. Literacy has received little attention in fragile X syndrome (FXS), the most common inherited cause of intellectual impairment. This study examined the literacy profile of FXS and tested phonological awareness and autism spectrum disorder (ASD) symptoms as predictors of literacy
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