An introduction of photobioreactor technology in mass culture of algea in order to improve the shrimp culture in Iran

Algae production in controlled condition is one one the most important subject that ought to studying . This kind of algae production can use for biosynthesis great syuffs like as vtamines and unsaturated fatty acids. For achieving this goal < this project was designed and done. At this project some procedures like steril cultivation < light controlling, remove and dissolving gases as oxygen and carbon dioxide, mixturing tank, intelligent sensor, biofilter purifying, dechloration vessel and dosing pumps are new phenomenas are used. Finally, chlorella sp from Gilan institute were culativated more than 16000000 cells per one millimeter

Comparison of neutralization potency across passive immunotherapy approaches as potential treatments for emerging infectious diseases

The use of passive immunotherapy, either as plasma or purified antibodies, has been recommended to treat the emerging infectious diseases (EIDs) in the absence of alternative therapeutic options. Here, we compare the neutralization potency of various passive immunotherapy approaches designed to provide the immediate neutralizing antibodies as potential EID treatments. To prepare human plasma and purified IgG, we screened and classified individuals into healthy, convalescent, and vaccinated groups against SARS-CoV-2 using qRT-PCR, anti-nucleocapsid, and anti-spike tests. Moreover, we prepared purified IgG from non-immunized and hyperimmunized rabbits against SARS-CoV-2 spike protein. Human and rabbit samples were used to evaluate the neutralization potency by sVNT. All vaccinated and convalescent human plasma and purified IgG groups, as well as purified IgG from hyperimmunized rabbits, had significantly greater levels of spike-specific antibodies than the control groups. Furthermore, when compared to the other groups, the purified IgG from hyperimmunized rabbits exhibited superior levels of neutralizing antibodies, with an IC50 value of 2.08 μg/ml. Additionally, our results indicated a statistically significant positive correlation between the neutralization IC50 value and the positive endpoint concentration of spike-specific antibodies. In conclusion, our study revealed that purified IgG from hyperimmunized animals has greater neutralization potency than other passive immunotherapy methods and may be the most suitable treatment of critically ill patients in EIDs