188 research outputs found
Sentiment Sentence Extraction Using a Hierarchical Directed Acyclic graph Structure and Bootstrap Approach
PACLIC / The University of the Philippines Visayas Cebu College Cebu City, Philippines / November 20-22, 200
Decreased cholinesterase level combined with renal dysfunction and sympathetic denervation associated with increased cardiac mortality in systolic heart failure
AimsCardiac mortality in patients with heart failure (HF) is likely to be aggravated by malnutrition, assessed by serum cholinesterase (ChE) level, as well as by kidney dysfunction or impairment of cardiac sympathetic denervation. Their prognostic interactions, however, have not been determined.MethodsA total of 991 systolic HF patients were enrolled in our HF database following clinical evaluation including evaluation of the nutrition state and assessment of standardized heart-to-mediastinum ratio (sHMR) of iodine-123-labeled meta-iodobenzylguanidine activity. Patients were followed up for an average of 43 months with the primary endpoint of fatal cardiac events (CEs).ResultsThe CE patient group had a lower level of ChE, lower estimated glomerular filtration rate (eGFR) and lower late sHMR than those in the non-CE patient group. A five-parameter model with the addition of serum ChE selected in the multivariate logistic analysis (model 2) significantly increased the AUC predicting risk of cardiac events compared with a four-parameter model without serum ChE (model 1), and net reclassification analysis also suggested that the model with the addition of serum cholinesterase significantly improved cardiac event prediction. Moreover, in overall multivariate Cox hazard analysis, serum ChE, eGFR and late sHMR were identified to be significant prognostic determinants. HF patients with two or all of the prognostic variables of serum ChE < 230 U/L, eGFR < 48.8 ml/min/1.73 m2 and late sHMR < 1.90 had significantly and incrementally increased CE rates compared to those in HF patients with none or only one of the prognostic variables.ConclusionDecreases in cholinesterase level and kidney function further increase cardiac mortality risk in HF patients with impairment of cardiac sympathetic innervation
Search for Outer Massive Bodies around Transiting Planetary Systems: Candidates of Faint Stellar Companions around HAT-P-7
We present results of direct imaging observations for HAT-P-7 taken with the
Subaru HiCIAO and the Calar Alto AstraLux. Since the close-in transiting planet
HAT-P-7b was reported to have a highly tilted orbit, massive bodies such as
giant planets, brown dwarfs, or a binary star are expected to exist in the
outer region of this system. We show that there are indeed two candidates for
distant faint stellar companions around HAT-P-7. We discuss possible roles
played by such companions on the orbital evolution of HAT-P-7b. We conclude
that as there is a third body in the system as reported by Winn et al. (2009,
ApJL, 763, L99), the Kozai migration is less likely while planet-planet
scattering is possible.Comment: 8 pages, 3 figures, 2 tables, PASJ in pres
Polarimetric Imaging of Large Cavity Structures in the Pre-transitional Protoplanetary Disk around PDS 70: Observations of the disk
We present high resolution H-band polarized intensity (PI; FWHM = 0."1: 14
AU) and L'-band imaging data (FWHM = 0."11: 15 AU) of the circumstellar disk
around the weak-lined T Tauri star PDS 70 in Centaurus at a radial distance of
28 AU (0."2) up to 210 AU (1."5). In both images, a giant inner gap is clearly
resolved for the first time, and the radius of the gap is ~70 AU. Our data show
that the geometric center of the disk shifts by ~6 AU toward the minor axis. We
confirm that the brown dwarf companion candidate to the north of PDS 70 is a
background star based on its proper motion. As a result of SED fitting by Monte
Carlo radiative transfer modeling, we infer the existence of an optically thick
inner disk at a few AU. Combining our observations and modeling, we classify
the disk of PDS 70 as a pre-transitional disk. Furthermore, based on the
analysis of L'-band imaging data, we put an upper limit mass of companions at
~30 to ~50MJ within the gap. Taking account of the presence of the large and
sharp gap, we suggest that the gap could be formed by dynamical interactions of
sub-stellar companions or multiple unseen giant planets in the gap.Comment: accepted by APJ
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